LEADER 01642nam 2200385 n 450 001 996388257303316 005 20231013195712.0 035 $a(CKB)1000000000635581 035 $a(EEBO)2240866499 035 $a(UnM)99841013 035 $a(EXLCZ)991000000000635581 100 $a19910314d1607 uy | 101 0 $aeng 135 $aurbn#|||a|bb| 200 10$aStrange histories, or Songes and sonets, of kings, princes, dukes, lordes, ladyes, knights, and gentlemen $every pleasant either to be read or songe: and a most excellent warning for all estates 210 $aImprinted at London $c[By W. White] for W. Barley, and are to be sold at his shop in Gratious streete against S. Peters Church$d1607 215 $a1 online resource ([80] p.) 300 $aBy Thomas Deloney. 300 $aBallads. 300 $aAn augmented edition, but lacking the music, of "Strange histories, of kings, princes, dukes earles, lords, ladies, knights, and gentlemen" (1602); three of the additions are signed T.R., A.C., and R. 300 $aPrinter's name from STC. 300 $aSignatures: A-E. 300 $aReproduction of the original in the Henry E. Huntington Library and Art Gallery. 330 $aeebo-0113 606 $aBallads, English$vEarly to 1800 615 0$aBallads, English 700 $aDeloney$b Thomas$f1543?-1600.$0137560 801 0$bCu-RivES 801 1$bCu-RivES 801 2$bCStRLIN 801 2$bWaOLN 801 2$bLML 912 $a996388257303316 996 $aStrange histories, or Songes and sonets, of kings, princes, dukes, lordes, ladyes, knights, and gentlemen$92381565 997 $aUNISA LEADER 04802nam 22005535 450 001 9910770243003321 005 20251009075205.0 010 $a981-9960-38-X 024 7 $a10.1007/978-981-99-6038-5 035 $a(MiAaPQ)EBC31020172 035 $a(Au-PeEL)EBL31020172 035 $a(CKB)29374582000041 035 $a(DE-He213)978-981-99-6038-5 035 $a(EXLCZ)9929374582000041 100 $a20231215d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNatural Product-based Synthetic Drug Molecules in Alzheimer's Disease $eTherapeutic & Theranostic Agents /$fedited by Abha Sharma, Gyan Prakash Modi 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023. 215 $a1 online resource (447 pages) 311 08$aPrint version: Sharma, Abha Natural Product-Based Synthetic Drug Molecules in Alzheimer's Disease Singapore : Springer,c2024 9789819960378 327 $aSection 1: Introduction of Alzheimer?s Disease -- Chapter 1: Alzheimer?s disease and drug targets -- Chapter 2: Oxidative stress and metals in Alzheimer?s disease -- Chapter 3: Neuroinflammation in Alzheimer?s disease -- Section 2: Biomarkers and Diagnosis in Alzheimer?s Disease -- Chapter 4: Biomarkers of Alzheimer?s disease -- Chapter 5: Naturally inspired fluorescent organic molecules as diagnostic and theranostic tools in Alzheimer?s disease -- Chapter 6: Nanostructure-based molecules as diagnostic and theranostic tools in AD -- Section 3: Drug derivatives: A strategy for new multifunctional drug development for Alzheimer?s Disease -- Chapter 7: Approved cholinesterase inhibitors-based derivatives: Synthesis and their biological evaluation -- Chapter 8: Memantine-based derivatives: Synthesis and their biological evaluation -- Section 4: Natural molecules inspired novel derivatives for Alzheimer?s Disease -- Chapter 9: Huperzine-based derivatives: Design, synthesis, and anti-Alzheimer activity -- Chapter 10: Polyphenol: Development of polyphenol-inspired derivatives targeting pathological factors of AD -- Chapter 11: Flavonoid-based derivatives for modulating various targets of Alzheimer?s disease -- Chapter 12: Vitamin-based derivatives for the management of Alzheimer?s disease -- Section 5: Metal dyshomeostasis: A hypothesis for developing drugs for the treatment of Alzheimer?s disease -- Chapter 13: Metal chelators as a potential therapeutic agent for Alzheimer?s disease -- Chapter 14: Ferroptosis modulators: A potential therapeutic target in Alzheimer?s disease -- Section 6. Natural products/Synthetic molecules as epigenetic modulators in Alzheimer?s disease -- Chapter 15. Sirtuin modulator: Design, synthesis, and biological evaluation -- Chapter 16. Histone deacetylase Inhibitors: Design, synthesis, and biological evaluation. 330 $aThis book illustrates the importance of natural products as the source for the development of novel drugs for the treatment of neurodegenerative disorders, including Alzheimer's disease. It also highlights the role of reactive oxygen species and altered metal homeostasis in the progression of Alzheimer?s disease and examines the potential of antioxidants and anti-chelating agents in the clinical intervention of neurodegenerative diseases. The book also discusses the role of neuroinflammation in the pathogenesis of Alzheimer?s disease. The chapters provide information about the drug targets, progress in the development of natural product-based therapeutics, biomarkers, fluorescent diagnostic tools, and theranostic for Alzheimer's disease. The book also provides information about the design and synthesis of natural product-based derivatives against the various targets of Alzheimer's disease including epigenetic targets and the metal dyshomeostasis hypothesis. Cutting across different disciplines, this book is a valuable source for neuroscientists, chemical biologists, pharmaceutical researchers, and synthetic biologists. 606 $aNeuropharmacology 606 $aPharmacology 606 $aNeurology 606 $aNeuropharmacology 606 $aPharmacology 606 $aNeurology 615 0$aNeuropharmacology. 615 0$aPharmacology. 615 0$aNeurology. 615 14$aNeuropharmacology. 615 24$aPharmacology. 615 24$aNeurology. 676 $a616.8311061 700 $aSharma$b Abha$01460238 701 $aModi$b Gyan Prakash$01460239 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910770243003321 996 $aNatural Product-Based Synthetic Drug Molecules in Alzheimer's Disease$93660125 997 $aUNINA