LEADER 03126nam 22006013u 450 001 9910511616503321 005 20210114194012.0 010 $a1-78560-441-4 035 $a(CKB)3710000000461613 035 $a(EBL)2141466 035 $a(MiAaPQ)EBC2141466 035 $a(Au-PeEL)EBL2141466 035 $a(CaPaEBR)ebr11086617 035 $a(OCoLC)918623995 035 $a(EXLCZ)993710000000461613 100 $a20150817d2015|||| u|| | 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAccounting in pluralistic societies (Special Issue)$b[electronic resource] 210 $aBradford $cEmerald Group Publishing Limited$d2015 215 $a1 online resource (209 p.) 225 1 $aAccounting, Auditing & Accountability Journal: Volume 28, Issue 5 300 $aDescription based upon print version of record. 311 $a1-78560-440-6 327 $aCover; EDITORIAL ADVISORY BOARD; Editorial; Guest Editor foreword; A sociological theory of corporate finance; Reexamination of the insurance-like effect of corporate social responsibility; Competition in corporate philanthropic disaster giving; Dynamics between currency and equity in Chinese markets; How strategy changes in different monetary policy conditions; The long-term performance of cross-border mergers and acquisitions; Business strategy, market competition and earnings management; Mandatory and voluntary information disclosure and the effects on financial analysts 327 $aThe moderating effect of social capital and cosmopolitanism on marketing capabilities 330 $aEcological (un)sustainability and social (in)justices are overarching themes in what has been called the critical (interdisciplinary) perspectives on accounting project (Roslender and Dillard, 2003; Broadbent and Laughlin, 2013). Their study can assume many hues and tints; employing various perspectives, theories, methods and methodologies across many issues and circumstances. The articles appearing here fall within this eclectic remit. This paper reviews and situates them within developments in contemporary political theory and critical policy analysis. The aim is to advance the project chara 410 0$aAccounting, Auditing & Accountability Journal: Volume 28, Issue 5 517 $aAccounting, Auditing & Accountability Journal 517 $aSpecial Issue 517 $aAccounting in pluralistic societies 606 $aAccounting 606 $aFinance, Public -- Accounting 608 $aElectronic books. 615 4$aAccounting. 615 4$aFinance, Public -- Accounting. 676 $a657 676 $a657.835 700 $aBrown$b Judy$01066492 701 $aDillard$b Jesse$01066493 701 $aHopper$b Trevor$0116401 701 $aParker$b Lee$01066494 701 $aGuthrie$b James$0116201 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910511616503321 996 $aAccounting in pluralistic societies (Special Issue)$92549297 997 $aUNINA LEADER 01439nam 2200349Ia 450 001 996387563203316 005 20221107141814.0 035 $a(CKB)4940000000087423 035 $a(EEBO)2240910576 035 $a(OCoLC)9922960100971 035 $a(EXLCZ)994940000000087423 100 $a20030717d1580 uy 0 101 0 $aeng 135 $aurbn||||a|bb| 200 12$aA discouerie of the countries of Tartaria, Scithia, & Cataya, by the northeast$b[electronic resource] $ewith the maners, fashions, and orders which are vsed in those countries. /$fSet foorth by Iohn Frampton merchaunt 210 $aJmprinted at London at the three Cranes in the Vintree, $cby Thomas Dawson.$d1580 215 $a[6], 40 [i.e. 80] p 300 $aTitle within border of printers' ornaments; initials. 300 $aPages numbered on recto only. 300 $aSignatures: [par.]?, A-E?. 300 $aImperfect: last leaf torn, with loss of text. 300 $aReproduction of original in: Lambeth Palace Library. 330 $aeebo-0076 607 $aAsia$xDescription and travel$vEarly works to 1800 607 $aAfrica, East$xDescription and travel$vEarly works to 1800 700 $aFrampton$b John$ffl. 1577-1596.$01002996 801 0$bEBK 801 1$bEBK 906 $aBOOK 912 $a996387563203316 996 $aA discouerie of the countries of Tartaria, Scithia, & Cataya, by the northeast$92416803 997 $aUNISA LEADER 06743nam 22007335 450 001 9910734833403321 005 20251008140521.0 010 $a3-031-31570-7 024 7 $a10.1007/978-3-031-31570-1 035 $a(CKB)27588190300041 035 $a(DE-He213)978-3-031-31570-1 035 $a(MiAaPQ)EBC30645966 035 $a(Au-PeEL)EBL30645966 035 $a(PPN)272256382 035 $a(EXLCZ)9927588190300041 100 $a20230713d2023 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAlzheimer?s Disease Research $eWhat Has Guided Research So Far and Why It Is High Time for a Paradigm Shift /$fby Christian Behl 205 $a1st ed. 2023. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023. 215 $a1 online resource (XXV, 652 p. 116 illus., 107 illus. in color.) 311 08$a9783031315695 327 $aChapter 1. Introduction -- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings -- Chapter 3. Alzheimer?s Disease Research After 1945: The Recommencement -- Chapter 4. Alzheimer?s Research Goes Deeper ? Ultrastructural Electron Microscopy Studies -- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer?s Disease -- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer?s Disease -- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer?s Disease -- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor -- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer?s Disease -- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals -- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas? -- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis -- Chapter 13. Focus on Tauopathies and Beyond -- Chapter 14. Alzheimer?s Research Gains Momentum and Spreads Out -- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally -- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way -- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias? -- Chapter 19. Driving Forces of Alzheimer?s Research Directions -- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last? -- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change". 330 $aThis book highlights the key phases and central findings of Alzheimer?s Disease research since the introduction of the label ?Alzheimer?s Disease? in 1910. The author, Christian Behl, puts dementia research in the context of the respective zeitgeist and summarizes the paths that have led to the currently available Alzheimer?s drugs. As the reader is taken through the major developments in Alzheimer's Disease research, particularly over the past thirty years, Behl poses critical questions: Why are the exact causes of Alzheimer's Disease still in the dark, despite all the immense, worldwide research efforts in academia as well as in the pharmaceutical industry? Why has the majority of an entire research field kept focusing on a single hypothesis that establishes the deposition of the amyloid beta peptide in the brain as the key trigger of Alzheimer's pathology, even though this concept has still not been convincingly proven in the clinics? Are there other hypotheses that might explain the pathogenesis of this complex brain disease, and if so, why were these perspectives not adequately followed? In this book, Behl tries to answer these questions. Starting with the historical background, the author illustrates the long and arduous research journey, its numerous setbacks, and the many alternative explanations for the disease, which have started gaining increasing attention and acceptance in the Alzheimer?s research community only more recently. With his deep dive into the history and progression of this research, including the most recent developments, Behl explains why he believes that it is high time to promote a paradigm shift in Alzheimer?s Disease research. The book is written for all researchers in the fields of neurobiology and neurodegeneration, as well as other biomedical fields, who would like to gain a broad and beyond the surface insight into (the key developments of) one of the most promoted research fields of our time. Withits extensive literature references and over 100 illustrations, the book is also attractive for students and interested lay persons. Elaborating on all the different aspects and research approaches of this research field, the author aims to convince the reader that the underlying causes of Alzheimer?s Disease may be much more complex than previously thought and that this must be considered for future research directions. While he hopes that the Alzheimer?s research community is finally ready to shed its ?amyloid-straitjacket? that has hampered progress for too long, he is also convinced that a much-needed paradigm shift can guide future Alzheimer?s Disease research and provide a new and broader perspective on this age-dependent brain disease. 606 $aNeurosciences 606 $aNeurology 606 $aNervous system$xDiseases 606 $aCognitive neuroscience 606 $aNeurophysiology 606 $aLearning$xPhysiological aspects 606 $aMemory$xPhysiological aspects 606 $aNeuroscience 606 $aNeurology 606 $aNeurological Disorders 606 $aCognitive Neuroscience 606 $aNeurophysiology 606 $aLearning and Memory 615 0$aNeurosciences. 615 0$aNeurology. 615 0$aNervous system$xDiseases. 615 0$aCognitive neuroscience. 615 0$aNeurophysiology. 615 0$aLearning$xPhysiological aspects. 615 0$aMemory$xPhysiological aspects. 615 14$aNeuroscience. 615 24$aNeurology. 615 24$aNeurological Disorders. 615 24$aCognitive Neuroscience. 615 24$aNeurophysiology. 615 24$aLearning and Memory. 676 $a612.8 676 $a616.83110072 700 $aBehl$b Christian$4aut$4http://id.loc.gov/vocabulary/relators/aut$01058337 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910734833403321 996 $aAlzheimer?s Disease Research$93566439 997 $aUNINA