LEADER 01495nam 2200397Ia 450 001 996386541503316 005 20221103135049.0 035 $a(CKB)4940000000081789 035 $a(EEBO)2240949409 035 $a(OCoLC)15237593 035 $a(EXLCZ)994940000000081789 100 $a19870225d1691 uy | 101 0 $aeng 135 $aurbn||||a|bb| 200 10$aHearts-ease in heart-trouble, or, A sovereign remedy against all trouble of heart that Christ's disciples are subject to$b[electronic resource] $e... prescribed by the great physician, the Lord Jesus Christ ... /$fby J.B., a servant of Jesus Christ 205 $aThe second edition. 210 $aLondon $cPrinted for J. Robinson$d1691 215 $aviii, 9-190 p 300 $aAttributed by Wing to Bardwood; also occasionally attributed to John Bunyan. 300 $a[2] p. of advertisements bound at end. 300 $aImperfect: tightly bound with loss of print. 300 $aReproduction of original in the Bodleian Library. 330 $aeebo-0014 606 $aChristian life 615 0$aChristian life. 700 $aBardwood$b James$01021799 701 $aBunyan$b John$f1628-1688.$0131402 801 0$bEAJ 801 1$bEAJ 801 2$bm/c 801 2$bEAJ 801 2$bWaOLN 906 $aBOOK 912 $a996386541503316 996 $aHearts-ease in heart-trouble, or, A sovereign remedy against all trouble of heart that Christ's disciples are subject to$92425879 997 $aUNISA LEADER 04040nam 22006855 450 001 9910878983003321 005 20240802130230.0 010 $a9789819734467$b(electronic bk.) 010 $z9789819734450 024 7 $a10.1007/978-981-97-3446-7 035 $a(MiAaPQ)EBC31579350 035 $a(Au-PeEL)EBL31579350 035 $a(CKB)33601168500041 035 $a(DE-He213)978-981-97-3446-7 035 $a(EXLCZ)9933601168500041 100 $a20240802d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAnalysis File of Drug-Induced Lung Injury $eExpert Opinion for Analysis of Big Data /$fby Akihiko Gemma 205 $a1st ed. 2024. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024. 215 $a1 online resource (122 pages) 311 08$aPrint version: Gemma, Akihiko Analysis File of Drug-Induced Lung Injury Singapore : Springer,c2024 9789819734450 327 $aPart I Understanding Drug-Induced Lung Injuries -- 1 Understanding Drug-Induced Lung Injuries -- Part 2 Actual Practice in Drug-Induced Lung Injuries of Each Drug -- 2 EGFR inhibitors (gefitinib, erlotinib, afatinib, osimertinib) -- 3 Anti-EGFR antibodies (cetuximab, panitumumab, necitumumab) -- 4 mTOR inhibitors (temsirolimus, everolimus) -- 5 Proteasome inhibitor (bortezomib) -- 6 Immune checkpoint inhibitors (nivolumab, pembrolizumab, atezolizumab, durvalumab) -- 7 Neoangiogenesis inhibitors (sunitinib, sorafenib, bevacizumab) -- 8 Other molecular targeted drugs (crizotinib, alectinib, etc.) -- 9 Antibody-drug conjugates (ADC) (trastuzumab emtansine, trastuzumab deruxtecan) -- 10 Anti-cancer drugs (TS-1, taxanes, CPT-11, platinum-containing drugs, etc.). 330 $aThis book describes the pathologic conditions of drug-induced lung injuries, monitoring strategies, and guides on how to interpret the evidence. It also dives into particular drugs that caused the disorder, such as EGFR inhibitors, anti-EGFR antibodies, mTOR inhibitors, proteasome inhibitors, immune checkpoint inhibitors, neoangiogenesis inhibitors, and other molecular targeted drugs. It outlines the analysis and interpretation of the post-marketing survey on surveillance of each drug for inducing pulmonary lesions presenting diffuse haziness. The data and analysis from this survey are valuable since a guideline is yet to be established due to limited clinical evidence and cases. As new drugs are developed, establishing treatment and event management is crucial. Thus, Drug-induced Pulmonary Disorder in Medical Oncology - Expert Opinion to Decipher Big Data summarizes the accumulated information to provide a foundation for further research advancement. The book offers a refreshing alternative to current approaches to medical oncology and respiratory diseases professionals and will also attract medical affairs members in global pharmaceutical companies. 606 $aRespiratory organs$xDiseases 606 $aMedical genetics 606 $aDiseases$xCauses and theories of causation 606 $aOncology 606 $aPharmacology 606 $aGenetics$xResearch 606 $aPneumology 606 $aClinical Genetics 606 $aPathogenesis 606 $aOncology 606 $aPharmacology 606 $aGenetics Research 615 0$aRespiratory organs$xDiseases. 615 0$aMedical genetics. 615 0$aDiseases$xCauses and theories of causation. 615 0$aOncology. 615 0$aPharmacology. 615 0$aGenetics$xResearch. 615 14$aPneumology. 615 24$aClinical Genetics. 615 24$aPathogenesis. 615 24$aOncology. 615 24$aPharmacology. 615 24$aGenetics Research. 676 $a616.2 700 $aGemma$b Akihiko$01765048 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910878983003321 996 $aAnalysis File of Drug-Induced Lung Injury$94206281 997 $aUNINA