LEADER 02218nam 2200433 n 450 001 996384620403316 005 20200824121358.0 035 $a(CKB)4940000000068325 035 $a(EEBO)2248515930 035 $a(UnM)99843815_8574e 035 $a(UnM)99843815_8574 035 $a(EXLCZ)994940000000068325 100 $a19910731d1573 uy | 101 0 $aeng 135 $aurbn||||a|bb| 200 14$aThe breuiary of Britayne$b[electronic resource] $eAs this most noble, and renowmed iland, was of auncient time deuided into three kingdomes, England, Scotland and Wales. Contaynyng a learned discourse of the variable state, [and] alteration therof, vnder diuers, as wel natural: as forren princes, [and] conquerours. Together with the geographicall description of the same, such as nether by elder, nor later writers, the like hath been set foorth before. Writen in Latin by Humfrey Lhuyd of Denbigh, a Cambre Britayne, and lately Englished by Thomas Twyne, Gentleman 210 $a[Imprinted at London $cBy Richard Iohnes: and are to be solde at his shop, ioynyng to the southwest doore of Paules Church]$d1573 215 $a[22], 96 leaves 300 $aA translation of: Commentarioli Britannicae descriptionis fragmentum. 300 $aPrinter's name and address from colophon. 300 $aRunning title reads: The breuiarie of Britayne. 300 $aIncludes index. 300 $aReproductions of the originals in the Henry E. Huntington Library and Art Gallery and the British Library. 300 $aAppears at reel 336 (Henry E. Huntington Library and Art Gallery copy) and at reel 809 (British Library copy). 330 $aeebo-0018 517 2 $aCommentarioli Britannicae descriptionis fragmentum. 517 2 $aBreuiarie of Britayne. 517 2 $aBreviarie of Britayne. 517 2 $aBreviary of Britayne. 606 $aBritons$vEarly works to 1800 607 $aGreat Britain$xDescription and travel$yTo 1600 615 0$aBritons 700 $aLlwyd$b Humphrey$f1527-1568.$0328758 701 $aTwyne$b Thomas$f1543-1613.$0845273 801 0$bCu-RivES 906 $aBOOK 912 $a996384620403316 996 $aThe breuiary of Britayne$92316723 997 $aUNISA LEADER 03554nam 2200445z- 450 001 9910136403503321 005 20210211 035 $a(CKB)3710000000612061 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/52951 035 $a(oapen)doab52951 035 $a(EXLCZ)993710000000612061 100 $a20202102d2015 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMechanisms underlying firing in healthy and sick human motoneurons 210 $cFrontiers Media SA$d2015 215 $a1 online resource (134 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-592-9 330 $aSince the latter half of the twentieth century an enormous amount of knowledge about mammalian motoneuron pools has been collected. This progress was enabled mostly by the development of the precise techniques of intracellular recordings in acute animal experiments, many of which were conducted under deep anaesthesia. Recently obtained evidence indicates that anaesthetics used at that times changed certain properties of the cell membrane, which might affect firing of the neuron. Experiments on normal humans gets around this problem, which lets one compare MN firing characteristics in humans and reduced preparations. Firing pattern of human motoneurons is obtained indirectly by recording from a few muscle fibres of a motor unit. Since there is one-to-one relationship between motor unit and motoneuron firing, the statistical analysis of motor unit firing is equivalent to the analysis of motoneuron firing. This analysis, based on the essential knowledge about motoneuron physiology, gained from the direct measurements in animal experiments and verified by computer simulations, allows one to draw conclusions about the physiological properties of human motoneurons. For obvious reasons, the deductions made on properties of human motoneuron from these analyses should be accepted with caution. On the other hand, human experiments provide the unique opportunity to study intact motoneurons during normal physiological behavior. Thus, combining information obtained from animal and human experiments, and computer simulations, gives insight into underexplored problems of motor control. This E-book contains a collection of articles with range of exciting findings on the physiology and pathology of human motoneurons. The collection covers such important issues concerning firing of healthy motoneurons as recruitment and rate coding as well as motoneuron excitability, discusses intrinsic motoneuron properties disclosed by studying double discharges, and provides information on broad spectrum of motoneuron pathology. It is our hope that this collection promotes further expansion of knowledge on human motoneurons. 606 $aNeurosciences$2bicssc 610 $aafterhyperpolarization and delayed depolarization 610 $aaxon and peripheral afferents 610 $aDouble and triple discharges 610 $aexcitability 610 $ahuman motoneuron discharge mechanisms 610 $amotoneuron pathology 610 $amotor unit 610 $aRecruitment and rate coding 615 7$aNeurosciences 700 $aAnnie Schmied$4auth$01331567 702 $aParveen N S Bawa$4auth 702 $aMaria Piotrkiewicz$4auth 906 $aBOOK 912 $a9910136403503321 996 $aMechanisms underlying firing in healthy and sick human motoneurons$93040439 997 $aUNINA