LEADER 00964nam--2200349---450- 001 990001593020203316 005 20050622163108.0 035 $a000159302 035 $aUSA01000159302 035 $a(ALEPH)000159302USA01 035 $a000159302 100 $a20040422d1966----km-y0itay0103----ba 101 0 $aspa 102 $aES 105 $a||||||||001yy 200 1 $aLecciones de linguistica espanola$fVicente Garcia de Diego 205 $a3. ed. 210 $aMadrid$cGredos$d1966 215 $a234 p.$d26 cm 410 0$12001 454 1$12001 461 1$1001-------$12001 700 1$aGARCÍA DE DIEGO,$bVicente$00 801 0$aIT$bsalbc$gISBD 912 $a990001593020203316 951 $aVI.5. Coll.6/ 4(II s C 1/4)$b28448 L.M.$cII s 959 $aBK 969 $aUMA 979 $aSIAV3$b10$c20040422$lUSA01$h1232 979 $aCOPAT6$b90$c20050622$lUSA01$h1631 996 $aLecciones de linguística española$9213651 997 $aUNISA LEADER 01547nam 2200373Ia 450 001 996383508003316 005 20210104162116.0 035 $a(CKB)1000000000586441 035 $a(EEBO)2240907351 035 $a(OCoLC)ocn166384443e 035 $a(OCoLC)166384443 035 $a(EXLCZ)991000000000586441 100 $a20070829d1517 uy 0 101 0 $aeng 135 $aurbn||||a|bb| 200 10$aSynonima magistri Joha[n]nis de Garlandia$b[electronic resource] cum expositione Magistri Galfridi Anglici, nuperrime correcta. 210 $aImpressus Londoniis $cPer wynanadum de worde, in parrochia sancte Bridgide in vico anglice nuncupato (the fletestrete) sub inter signo solis commorantem, Anno d[omi]ni millesimo quingentesimo decimoseptimo vicesimo die mensis Februarii. [1517] 215 $a[107] p 300 $aImprint from colophon. 300 $aAn edition of: Synonyma. 300 $aPrinter's device at colophon (McK. 19). 300 $aSignatures: A⸠Bâ´ C⸠Dâ´ E⸠Fâ´ G⸠Hâ´ Iâ´. 300 $aReproduction of original in: British Library. 330 $aeebo-0018 606 $aLatin language$xSynonyms and antonyms$vEarly works to 1800 615 0$aLatin language$xSynonyms and antonyms 700 $aJohn$cof Garland,$fca. 1195-ca. 1272.$0181432 701 $aGalfridus$cAnglicus,$ffl. 1440.$0682023 801 0$bUMI 801 1$bUMI 906 $aBOOK 912 $a996383508003316 996 $aSynonima magistri Johanis de Garlandia$92422930 997 $aUNISA LEADER 01171oam 2200361Ka 450 001 9910698275403321 005 20120521151143.0 035 $a(CKB)4330000001279867 035 $a(OCoLC)67301464 035 $a(EXLCZ)994330000001279867 100 $a20060421d2004 ua 0 101 0 $aeng 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aThirstin's wacky water adventure$b[electronic resource] 210 1$a[Washington, D.C.] :$cUnited States Environmental Protection Agency, Office of Water,$d[2004] 215 $a15 pages $cdigital, PDF file 300 $aTitle from title screen (viewed on Apr. 21, 2006). 300 $a"06/2004." 300 $a"EPA 816-K-04-002." 606 $aWater$zUnited States$vJuvenile literature 606 $aColoring books$zUnited States$vJuvenile literature 615 0$aWater 615 0$aColoring books 712 02$aUnited States.$bEnvironmental Protection Agency.$bOffice of Water. 801 0$bGPO 801 1$bGPO 801 2$bGPO 906 $aBOOK 912 $a9910698275403321 996 $aThirstin's wacky water adventure$93200370 997 $aUNINA LEADER 02506nam 2200481z- 450 001 9910743270903321 005 20230911 035 $a(CKB)5690000000228599 035 $a(oapen)doab113972 035 $a(EXLCZ)995690000000228599 100 $a20230920c2023uuuu -u- - 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMolecular Research of Alzheimer's Disease 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2023 215 $a1 online resource (206 p.) 311 08$a3-0365-8439-0 330 $aThe incidence and prevalence of Alzheimer's Disease are increasing worldwide due to aging and comorbidities. The classical neuropathogenetic model, which concentrates on brain amyloid plaque deposition, neurofibrillary tangles, and cholinergic system dysfunction, is being expanded and integrated with newer molecular models. Understanding the relationships between the classical pathogenetic pathways and newer hypotheses is imperative for guiding future research and developing effective drugs. The existence of newer molecular mechanisms such as risk factors, comorbidities like vascular diseases and diabetes mellitus, and neuroanatomical/neurofunctional alterations as blood-brain barrier breakdown and neurovascular unit dysfunction, offer potential targets to improve Alzheimer's Disease diagnosis and treatment. This reprint provides an overview of the pathophysiologic role of newer and older molecular mechanisms of Alzheimer's Disease, shedding light on new insights for the development of new therapeutic approaches. It also highlights newer candidate markers of disease onset and progression. 606 $aMedicine and Nursing$2bicssc 606 $aNeurology and clinical neurophysiology$2bicssc 610 $aAlzheimer&rsquo 610 $aatherosclerosis 610 $abiomarkers 610 $ablood&ndash 610 $abrain barrier 610 $abrain barrier disruption 610 $adiagnosis 610 $aMCI 610 $amild cognitive impairment 610 $aneurovascular unit 610 $aneurovascular unit dysfunction 610 $aprognosis 610 $as disease 610 $atype 3 diabetes mellitus 615 7$aMedicine and Nursing 615 7$aNeurology and clinical neurophysiology 906 $aBOOK 912 $a9910743270903321 996 $aMolecular Research of Alzheimer's Disease$93560507 997 $aUNINA