LEADER 04703oam 2200601I 450 001 996320721103316 005 20230721031505.0 010 $a0-429-12715-4 010 $a1-280-73308-X 010 $a9786610733088 010 $a1-4200-0584-7 024 7 $a10.1201/9781420005844 035 $a(CKB)1000000000468005 035 $a(EBL)282790 035 $a(OCoLC)317753693 035 $a(SSID)ssj0000262561 035 $a(PQKBManifestationID)11210147 035 $a(PQKBTitleCode)TC0000262561 035 $a(PQKBWorkID)10270675 035 $a(PQKB)10297791 035 $a(MiAaPQ)EBC282790 035 $a(EXLCZ)991000000000468005 100 $a20180331d2007 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aTRP ion channel function in sensory transduction and cellular signaling cascades /$fedited by Wolfgang B. Liedtke, with Stefan Heller 210 1$aBoca Raton, FL :$cCRC/Taylor & Francis,$d2007. 215 $a1 online resource (502 p.) 225 1 $aFrontiers in neuroscience 300 $aDescription based upon print version of record. 311 $a0-8493-4048-9 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Series Preface; Preface; The Editors; Contributors; Abstract; Contents; Chapter 1. The TRPC Family of Ion Channels: Relation to the TRP Superfamily and Role in Receptor- and Store- Operated Calcium Entry; Chapter 2. Multiple Mechanisms of TRPC Activation; Chapter 3. TRPC2 and the Molecular Biology of Pheromone Detection in Mammals; Chapter 4. TRP Channels and Axon Pathfinding; Chapter 5. TRPV1 Receptors and Signal Transduction; Chapter 6. Complex Regulation of TRPV1 by Vanilloids; Chapter 7. TRPV2: A Calcium- Permeable Cation Channel Regulated by Insulin-Like Growth Factors 327 $aChapter 8. Molecular Mechanisms of TRPV4 Gating Chapter 9. TRPV4: A Multifunctional Nonselective Cation Channel with Complex Regulation; Chapter 10. TRPV4 and TRPM3 as Volume-Regulated Cation Channels; Chapter 11. TRPA1:A Sensory Channel of Many Talents; Chapter 12. TRPA1 in Auditory and Nociceptive Organs; Chapter 13. TRPM8: The Cold and Menthol Receptor; Chapter 14. Activation Mechanisms and Functional Roles of TRPP2 Cation Channels; Chapter 15. The Ca2+-Activated TRP Channels: TRPM4 and TRPM5; Chapter 16. Genetics Can Be Painless: Molecular Genetic Analysis of Nociception in Drosophila 327 $aChapter 17. TRPV Family Ion Channels and Other Molecular Components Required for Hearing and Proprioception in Drosophila Chapter 18. The TRPV Channel in C. elegans Serotonergic Neurons; Chapter 19. TRP Channel Functioning in Mating and Fertilization; Chapter 20. The Role of TRP Channels in Thermosensation; Chapter 21. Voltage and Temperature Gating of ThermoTRP Channels; Chapter 22. TRPV Channels' Function in Osmo- and Mechanotransduction; Chapter 23. TRP Channel Trafficking; Chapter 24. Protein-Protein Interactions in TRPC Channel Complexes 327 $aChapter 25. Structural Insights into the Function of TRP Channels Chapter 26. Functional Significance of Transient Receptor Potential Channels in Vascular Function; Chapter 27. Role of TRPV4 in the Mechanotransduction of Shear Stress in Endothelial Cells; Chapter 28. A New Insight into the Function of TRPV2 in Circulatory Organs; Chapter 29. The Role of TRPV 4 in the Kidney; Chapter 30. The TRPV4 Channel in Ciliatd Epithelia; Chapter 31. Protease-Activated Receptors: Mechanisms by Which Proteases Sensitize TRPV Channels to Induce Neurogenic Inflannation and Pain; Index; Back Cover 330 $aSince the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of stimuli from both within and outside the cell body. How we sense heat and cold, how we taste food, how eggs are fertilized, how the heart expands and contracts is each dependent on the function of these channels. While no single book could 410 0$aFrontiers in neuroscience (Boca Raton, Fla.) 606 $aTRP channels 615 0$aTRP channels. 676 $a572.3 676 $a572/.3 701 $aLiedtke$b Wolfgang B$01236746 701 $aHeller$b Stefan$01236747 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a996320721103316 996 $aTRP ion channel function in sensory transduction and cellular signaling cascades$92871472 997 $aUNISA