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035   $a(MiAaPQ)EBC4355749
035   $a(DE-B1597)462962
035   $a(OCoLC)939265274
035   $a(OCoLC)979585860
035   $a(OCoLC)980240909
035   $a(DE-B1597)9783110468755
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100   $a20160210h20152015  uy             0
101 0 $aeng
135   $aurcnu||||||||
181   $2rdacontent
182   $2rdamedia
183   $2rdacarrier
200 10$aBiomedical chemistry $ecurrent trends and developments /$fNuno Vale ; managing editor, Anna Rulka ; language editor, Reuben Hudson & Michael Jones
210  1$aBerlin, [Germany] :$cDe Gruyter Open,$d2015.
210  4$d©2015
215   $a1 online resource (361 pages) $cillustrations, tables
311   $a3-11-046874-3 
320   $aIncludes bibliographical references and index.
327   $tFront matter --$tContents --$tPreface --$tSection 1: Chemical Principles in Drug Design and Discovery --$t1.1 Functional Groups of Biomolecules and their Reactions /$rPinto, Diana C. G. A. / Pereira, João M. P. / Silva, Artur M. S. --$t1.2 Designing Covalent Inhibitors: A Medicinal Chemistry Challenge /$rLopes, Francisca / Santos, Maria M. M. / Moreira, Rui --$tSection 2: Chemical Basis of Drug Action and Diseases --$t2.1 Pharmacokinetics and Bioanalysis to Improve Drug Development /$rFortuna, Ana / Alves, Gilberto / Falcão, Amílcar --$t2.2 Translational Research in Endocrinology and Neuroimmunology Applied to Depression /$rWong, Ma-Li / Lewis, Martin / Licinio, Julio --$t2.3 Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profile /$rPereira, Cidália / Monteiro, Rosário / João Martins, Maria --$t2.4 Brain Neurochemistry and Cognitive Performance: Neurotransmitter Systems /$rLobo, Andrea / Summavielle, Teresa --$tSection 3: Strategies to Develop New and Better Drugs --$t3.1 Amino Acids and Peptides in Medicine: Old or New Drugs? /$rVale, Nuno --$t3.2 Targeting Calcium-mediated Excitotoxicity in the CNS /$rChambers, James J. --$t3.3 Strategies for Conversion of Peptides to Peptidomimetic Drugs /$rFransson, Rebecca / Sköld, Christian / Sandström, Anja --$t3.4 Synthetic Vs. Natural Bioactive Compounds Against Tropical Disease /$rPybus, Brandon S. --$t3.5 Current Trends and Developments for Nanotechnology in Cancer /$rFerreira, Mónica / Almeida, Patrick / Shahbazi, Mohammad-Ali / Correia, Alexandra / Santos, Hélder A. --$tIndex
330   $aBiomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry.
606   $aPharmaceutical chemistry
608   $aElectronic books.
610   $amedicinal chemistry, natural products, drug design, drug discovery, translational research.
615  0$aPharmaceutical chemistry.
676   $a615.19
700   $aVale$b Nuno$0886746
702   $aRulka$b Anna
702   $aHudson$b Reuben
702   $aJones$b Michael
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a996308772703316
996   $aBiomedical chemistry$91980408
997   $aUNISA