LEADER 04628nam 2200685Ia 450 001 996218269803316 005 20240418063421.0 010 $a1-281-32201-6 010 $a9786611322014 010 $a0-470-75061-8 010 $a0-470-75022-7 035 $a(CKB)1000000000403880 035 $a(EBL)351017 035 $a(OCoLC)437214022 035 $a(SSID)ssj0000123721 035 $a(PQKBManifestationID)11159782 035 $a(PQKBTitleCode)TC0000123721 035 $a(PQKBWorkID)10011112 035 $a(PQKB)10632791 035 $a(MiAaPQ)EBC351017 035 $a(Au-PeEL)EBL351017 035 $a(CaPaEBR)ebr10232989 035 $a(CaONFJC)MIL132201 035 $a(EXLCZ)991000000000403880 100 $a20051129d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aClinical trials explained$b[electronic resource] $ea guide to clinical trials in the NHS for healthcare professionals /$feditors, Derek Stewart ... et al. ; produced by the British Medical Journal (BMJ), in association with the National Translational Cancer Research Network (NTRAC) and Emergency Care Research Institute (ECRI) 205 $a1st ed. 210 $aMalden, MA $cBlackwell Pub.$dc2006 215 $a1 online resource (114 p.) 300 $aDescription based upon print version of record. 311 $a0-7279-1858-3 320 $aIncludes bibliographical references and index. 327 $aClinical Trials Explained: A Guide to Clinical Trials in the NHS for Healthcare Professionals; Contents; Preface; Acknowledgements; Chapter 1 Overview and Purpose of this Guide to Clinical Trials in the NHS; Overview and purpose of this guide; Who should use this guide to clinical trials in the NHS?; Chapter 2 Clinical Trials Explained; What are clinical trials?; Why are clinical trials needed?; Who is involved in a clinical trial?; How are clinical trials designed and approved?; Progression of a medical intervention through the clinical trial phases; Summary 327 $aChapter 3 Clinical Trial Approval, Regulation and FundingHow are clinical trials approved and regulated?; Ethical approval; Informed consent; How are trials managed?; Who pays for a clinical trial?; Summary; Chapter 4 Understanding Clinical Trial Design and Results; Understanding randomisation and blinding in clinical trials; Understanding controls and placebos; Why are placebos used in clinical trials?; What about trials that are not controlled or blinded?; Understanding clinical trial results; Summary; Chapter 5 Questions About Clinical Trials: A Framework for Discussion 327 $aWhat are patients' rights?Why do patients take part in clinical trials?; Why do patients decline to take part in a clinical trial or withdraw from a clinical trial they are involved in?; How can patients be empowered during their involvement in a clinical trial?; Will patients involved in clinical trials need extra help and support from their carers?; What are the likely costs of and reimbursement for patients participating in clinical trials?; Summary; Appendix A Finding Out About Clinical Trials that are Currently or Soon to be Recruiting 327 $aAppendix B ECRI Evidence Report: Patients' Reasons for Participation in Clinical Trials and Effect of Trial Participation on Patient OutcomesGlossary; Index 330 $aWhat will happen during and after a clinical trial?How will a trial affect my quality of life?What are the benefits and risks of a trial?What does giving consent mean and what will it involve?Will I incur costs during and because of the trial? These are the questions that should be raised every time a health care professional talks through with a patient the pros and cons of entering a clinical trial. Clinical Trials Explained has been designed in consultation with doctors and patients who have taken part in trials, providing an essential and detailed gu 606 $aClinical trials$zGreat Britain 606 $aClinical trials$xDecision making 606 $aNational health services$zGreat Britain 615 0$aClinical trials 615 0$aClinical trials$xDecision making. 615 0$aNational health services 676 $a610.72/4 676 $a615.50724 701 $aStewart$b Derek$f1951-$0939840 712 02$aNational Translational Cancer Research Network. 712 02$aEmergency Care Research Institute. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996218269803316 996 $aClinical trials explained$92119014 997 $aUNISA