LEADER 03003nam 22005654a 450 001 996214620003316 005 20230617005506.0 010 $a1-280-19666-1 010 $a9786610196661 010 $a0-470-79942-0 010 $a0-470-99477-0 010 $a1-4051-4616-8 035 $a(CKB)1000000000342020 035 $a(EBL)233011 035 $a(OCoLC)437146395 035 $a(SSID)ssj0000096762 035 $a(PQKBManifestationID)11120003 035 $a(PQKBTitleCode)TC0000096762 035 $a(PQKBWorkID)10082623 035 $a(PQKB)10304098 035 $a(MiAaPQ)EBC233011 035 $a(EXLCZ)991000000000342020 100 $a20030829d2004 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAcquired long QT syndrome$b[electronic resource] /$fA. John Camm, Yee Guan Yap, Marek Malik 210 $aMalden, Mass. $cFutura$dc2004 215 $a1 online resource (208 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-1838-5 320 $aIncludes bibliographical references and index. 327 $aAcquired Long QT Syndrome; Contents; Preface; 1 Introduction; 2 Mechanisms of acquired QT prolongation and torsades de pointes; 3 Measurement of QT interval and repolarization assessment; 4 Introduction to drug-induced long QT syndrome; 5 Risk of QT prolongation and torsades de pointes with antiarrhythmic drugs; 6 Risk of QT prolongation and torsades de pointes with antihistamines; 7 Risk of QT prolongation and torsades de pointes with psychotropic drugs; 8 Risk of QT prolongation and torsades de pointes with antimicrobial and antimalarial drugs 327 $a9 Risk of QT prolongation and torsades de pointes with prokinetics and miscellaneous other drugs10 Acquired long QT syndrome secondary to cardiac conditions; 11 Acquired long QT syndrome secondary to noncardiac conditions; 12 Perspective on drug-induced repolarization changes; Index 330 $aIn recent years there has been considerable interest in the diagnosis and understanding of ventricular repolarisation, particularly the QT interval prolongation and abnormal T and T/U wave morphology associated with torsades de pointes. Advances in ion channel cloning have greatly improved our understanding of the role of ionic channels in mediating cardiac repolarisation. Unfortunately, it is increasingly recognised that a number of drugs, both those associated with altering repolarisation, and others for non-cardiac conditions can increase the propensity for polymorphic ventricular tachycard 606 $aLong QT syndrome 615 0$aLong QT syndrome. 676 $a616.128 700 $aCamm$b A. John$0881285 701 $aYap$b Yee Guan$0755850 701 $aMalik$b Marek$0881286 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996214620003316 996 $aAcquired long QT syndrome$91968214 997 $aUNISA