LEADER 03352nam 2200589 a 450 001 996209973803316 005 20230213211620.0 010 $a1-280-76869-X 010 $a9786613679468 010 $a0-470-71947-8 010 $a0-470-71702-5 035 $a(CKB)1000000000687471 035 $a(EBL)703793 035 $a(SSID)ssj0000715166 035 $a(PQKBManifestationID)11421740 035 $a(PQKBTitleCode)TC0000715166 035 $a(PQKBWorkID)10700724 035 $a(PQKB)11586137 035 $a(MiAaPQ)EBC703793 035 $a(OCoLC)264624145 035 $a(EXLCZ)991000000000687471 100 $a20120309d1967 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCiba Foundation Symposium$b[electronic resource] $edevelopment of the lung /$fedited by A.V.S. de Reuck and Ruth Porter 210 $aLondon $cJ. & A. Churchill$d1967 215 $a1 online resource (466 p.) 225 1 $aCiba Foundation symposium 300 $aProceedings of the Symposium on Development of the Lung, held Nov. 1-3, 1965. 311 $a0-470-72291-6 320 $aIncludes bibliographical references and indexes. 327 $aDEVELOPMENT OF THE LUNG; Contents; Chairman's opening remarks; Gas transport from the external environment to the cell; Discussion; Variation of chemical potential with temperature*; Some implications of the dynamics of gas transfer in water-breathing dogs; Discussion; Evolution between air and water; Discussion; Quantitative aspects of vertebrate gas exchange; Discussion; The embryology of the lung; Discussion; Postnatal growth of the lung and pulmonary gas-exchange capacity; Discussion; A morphological contribution to the development of the human lung: observations in the non-retracted lung 327 $aGeneral DiscussionThe alveolar lining layer; Discussion; Physiological consequences of the apposition of blood and gas in the lung; Discussion; The alveolar lining layer; Discussion; General Discussion; Comparative properties of the lungs and the placenta: a graphical analysis of placental gas exchange; Discussion; The oxygen supply of the foetus; Discussion; Carriage of oxygen in the blood of the foetus; Discussion; Oxygen consumption of the placenta and foetal membranes in the sheep; Discussion; General Discussion; Carbon monoxide and oxygen saturation; Oxygen consumption and the placenta 327 $aSurface-active lipoproteinlnitiation of respiration; Discussion; Pulmonary circulation in the foetus and the newborn; Discussion; Uptake of liquid from the lungs at the start of breathing; Group Discussion; Discussion; Surfactant and lung collapse; Observations of homoeostatic regulation; Nature of homoeostatic regulation; Evolution of homoeostatic regulation; Transport across membranes; Chairman's closing remarks; Author Index; Subject Index 410 0$aCiba Foundation symposium. 606 $aLungs$vCongresses 606 $aRespiration$vCongresses 615 0$aLungs 615 0$aRespiration 676 $a600 701 $aDe Reuck$b Anthony V. S$0290946 701 $aPorter$b Ruth$064811 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996209973803316 996 $aCiba Foundation Symposium$93005136 997 $aUNISA LEADER 03992nam 22004935 450 001 9910298398603321 005 20251116204544.0 010 $a3-319-90808-1 024 7 $a10.1007/978-3-319-90808-3 035 $a(CKB)4100000005323560 035 $a(DE-He213)978-3-319-90808-3 035 $a(MiAaPQ)EBC5479051 035 $z(PPN)25885765X 035 $a(PPN)229503322 035 $a(EXLCZ)994100000005323560 100 $a20180728d2018 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aThe Adenosine Receptors /$fedited by Pier Andrea Borea, Katia Varani, Stefania Gessi, Stefania Merighi, Fabrizio Vincenzi 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2018. 215 $a1 online resource (XX, 593 p. 71 illus., 29 illus. in color.) 225 1 $aThe Receptors,$x1048-6909 ;$v34 311 08$a3-319-90807-3 327 $aPurinergic signalling: an historical overview -- Regulation of extracellular adenosine -- Adenosine receptors: structure, distribution and signal transduction -- Binding thermodynamic characteristics of adenosine receptor ligands -- A1 adenosine receptor agonists, antagonists and allosteric modulators -- A2A adenosine receptor: structure, function and medicinal chemistry -- Medicinal chemistry of A2B adenosine receptors -- A3 adenosine receptor: medicinal chemistry of orthosteric and allosteric ligands and structural probing -- Adenosine Receptors and Neuroinflammation -- Adenosine receptors as paradigm to identify dimer/oligomers of G-protein-coupled receptors and as targets in Parkinson?s disease -- Adenosine receptors in Alzheimer?s disease -- What is the role of adenosine receptors in Huntington Disease? -- Adenosine receptors: a novel target for homeostatic control of cognition -- Role of Adenosine Receptors in Epileptic Seizures -- Adenosine signaling in brain Ischemia -- Adenosine and traumatic brain injury -- Adenosine and its receptors in pain -- Adenosine signalling in the injured heart -- Adenosine receptors in the lungs -- Adenosine and renal function in health and disease -- Adenosine regulation of the immune system -- Adenosine receptors regulate skeletal biology -- Adenosine receptors in gestational diabetes mellitus and obesity -- Adenosine receptors: current research and their involvement in cancer -- Adenosine receptors as a biological pathway for pulsed electromagnetic fields. 330 $aThis book traces the history of adenosine receptor research from molecular biology to medicinal chemistry to behavior, including their implications in disease and potential strategies as therapeutic targets. It provides the reader with a comprehensive overview of the adenosine receptors that includes information on all subtypes - A1, A2A, A2B and A3. Aspects addressed include the most up to date information on their functional distribution in the nervous and peripheral systems, behavioral roles in inflammation, cancer, pain and neurological diseases such as Huntington?s disease, Epilepsy, Parkinson?s disease and Alzheimer?s disease. 410 0$aThe Receptors,$x1048-6909 ;$v34 606 $aNeurochemistry 606 $aNeurochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/B18010 615 0$aNeurochemistry. 615 14$aNeurochemistry. 676 $a612.8042 702 $aBorea$b Pier Andrea$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aVarani$b Katia$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGessi$b Stefania$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMerighi$b Stefania$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aVincenzi$b Fabrizio$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298398603321 996 $aThe Adenosine Receptors$92508883 997 $aUNINA