LEADER 03882nam 22007452 450 001 9910454633503321 005 20151005020622.0 010 $a1-139-93145-8 010 $a1-107-20072-5 010 $a9786612001826 010 $a1-282-00182-5 010 $a0-511-48018-0 010 $a0-511-48098-9 010 $a0-511-47785-6 010 $a0-511-47633-7 010 $a0-511-75951-7 010 $a0-511-47937-9 035 $a(CKB)1000000000702638 035 $a(EBL)412763 035 $a(OCoLC)437089919 035 $a(SSID)ssj0000151272 035 $a(PQKBManifestationID)11910602 035 $a(PQKBTitleCode)TC0000151272 035 $a(PQKBWorkID)10282001 035 $a(PQKB)10965726 035 $a(UkCbUP)CR9780511759512 035 $a(MiAaPQ)EBC412763 035 $a(Au-PeEL)EBL412763 035 $a(CaPaEBR)ebr10277535 035 $a(CaONFJC)MIL200182 035 $a(EXLCZ)991000000000702638 100 $a20100430d2009|||| uy| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEvidence-based diagnosis /$fThomas B. Newman, Michael A. Kohn$b[electronic resource] 210 1$aCambridge :$cCambridge University Press,$d2009. 215 $a1 online resource (xiii, 295 pages) $cdigital, PDF file(s) 225 1 $aPractical Guides to Biostatistics and Epidemiology 300 $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015). 311 $a0-521-71402-8 311 $a0-521-88652-X 320 $aIncludes bibliographical references and index. 327 $aIntroduction: Understanding diagnosis and diagnostic testing -- Reliability and measurement error -- Dichotomous tests -- Multilevel and continuous tests -- Critical appraisal of studies of diagnostic tests -- Screening tests -- Prognostic tests and studies -- Multiple tests and multivariable decision rules -- Quantifying treatment effects using randomized trials -- Alternatives to randomized trials for estimating treatment effects -- Understanding P-values and confidence intervals -- Challenges for evidence-based diagnosis. 330 $aEvidence-Based Diagnosis explains diagnostic, screening, and prognostic tests in clinical medicine. The authors' approach is based on many years of experience teaching physicians in a clinical research training program. Although needing only a minimum of mathematics, the quantitative discussions in this book are deeper and more rigorous than in most introductory texts. The book includes numerous worked examples and 60 problems (with answers) based on real clinical situations and journal articles. This book is a great choice for anyone looking to select, develop, or apply medical tests. Topics covered include: the diagnostic process; test reliability and accuracy; testing and treatment thresholds; critical appraisal of studies of diagnostic, screening and prognostic tests; test independence and methods of combining tests; quantifying treatment benefits using randomized trials and observational studies; Bayesian interpretation of P values and confidence intervals; challenges for evidence-based diagnosis; likelihood ratios and ROC curves. 410 0$aPractical Guides to Biostatistics and Epidemiology 606 $aDiagnosis 606 $aEvidence-based medicine 606 $aFunction tests (Medicine)$xEvaluation 606 $aDiagnosis$xResearch 615 0$aDiagnosis. 615 0$aEvidence-based medicine. 615 0$aFunction tests (Medicine)$xEvaluation. 615 0$aDiagnosis$xResearch. 676 $a616.07/5 700 $aNewman$b Thomas B.$0103620 702 $aKohn$b Michael A. 801 0$bUkCbUP 801 1$bUkCbUP 906 $aBOOK 912 $a9910454633503321 996 $aEvidence-based diagnosis$92477574 997 $aUNINA LEADER 01466nas 2200541-a 450 001 996208158403316 005 20230715213020.0 011 $a1421-9751 035 $a(DE-599)ZDB1482041-9 035 $a(OCoLC)44640098 035 $a(CKB)954925388221 035 $a(CONSER)--2011250846 035 $a(EXLCZ)99954925388221 100 $a20000724a19709999 s-- - 101 0 $aeng 135 $aurmn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCardiology 210 $a[Basel, Switzerland] $cKarger 300 $aRefereed/Peer-reviewed 311 $a0008-6312 531 $aCARDIOLOGY BASEL 606 $aCardiology$vPeriodicals 606 $aCardiology 606 $aCardiovascular Diseases 606 $aCardiovascular Surgical Procedures 606 $aCardiology$2fast$3(OCoLC)fst00847121 606 $aKardiologie$2gnd 606 $aZeitschrift$2gnd 606 $aOnline-Ressource$2gnd 608 $aPeriodical 608 $aPeriodicals.$2fast 608 $aPeriodicals.$2lcgft 615 0$aCardiology 615 2$aCardiology 615 2$aCardiovascular Diseases 615 2$aCardiovascular Surgical Procedures 615 7$aCardiology. 615 7$aKardiologie 615 7$aZeitschrift 615 7$aOnline-Ressource 676 $a616.1/2/005 906 $aJOURNAL 912 $a996208158403316 996 $aCardiology$91924907 997 $aUNISA