LEADER 03640nam 2200637 a 450 001 996206959203316 005 20230213211647.0 010 $a0-470-72066-2 010 $a1-280-78395-8 010 $a9786613694348 010 $a0-470-71835-8 035 $a(CKB)1000000000688137 035 $a(EBL)703905 035 $a(OCoLC)797918478 035 $a(SSID)ssj0000715480 035 $a(PQKBManifestationID)11404029 035 $a(PQKBTitleCode)TC0000715480 035 $a(PQKBWorkID)10700968 035 $a(PQKB)10611063 035 $a(MiAaPQ)EBC703905 035 $a(Au-PeEL)EBL703905 035 $a(CaPaEBR)ebr10575468 035 $a(CaONFJC)MIL369434 035 $a(EXLCZ)991000000000688137 100 $a19810925d1981 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMicroenvironments in haemopoietic and lymphoid differentiation$b[electronic resource] /$f[Ruth Porter and Julie Whelan, editors] 210 $aLondon $cPitman ;$aSummit, N.J. $cDistributed in North America by CIBA Pharmaceutical Co.$d1981 215 $a1 online resource (362 p.) 225 1 $aCiba Foundation symposium ;$v84 (new ser.) 300 $aDescription based upon print version of record. 311 $a0-470-66394-4 311 $a0-272-79636-0 320 $aIncludes bibliographical references and indexes. 327 $aMicroenvironments in haemopoietic and lymphoid differentiation; Contents; Introduction: signals, receptors and repertoire in haemopoietic differentiation; Haemopoiesis in mammalian bone marrow; Discussion; Self-renewing haemopoietic progenitor cells and the factors controlling proliferation and differentiation; Discussion; Haemopoietic microenvironments in vitro: ultrastructural aspects; Discussion; Regulation and localization of lymphocyte production in the bone marrow; Discussion; Environmental factors in haemopoietic failure in humans; Discussion 327 $aMapping cell surface antigen expression on haemopoietic progenitor cells using monoclonal antibodiesDiscussion; Lymphoid differentiation in vitro; Discussion; Microanatomy of the thymus: its relationship to T cell differentiation; Discussion; Expression and function of major histocompatibility complex antigens in the developing thymus: studies on normal and nude mice; Discussion; The human thymic microenvironment; Discussion; Cellular and molecular signals in T cell differentiation; Discussion; General discussion: tolerance and diversification of the T cell repertoire 327 $aHistophysiology of follicular structures and germinal centres in relation to B cell differentiationDiscussion; The role of germinal centres in the generation of immunological memory; Discussion; Antigen-presenting cells, including Langerhans cells, veiled cells and interdigitating cells; Discussion; Differentiation of function among antigen-presenting cells; Discussion; Final general discussion T cell subsets and T cell function; Decision-making in development; Chairman's summing-up; Index of contributors; Subject index 410 0$aCiba Foundation symposium ;$vnew ser. 84. 606 $aBlood cells$vCongresses 606 $aCell differentiation$vCongresses 615 0$aBlood cells 615 0$aCell differentiation 676 $a596/.01/13 701 $aPorter$b Ruth$064811 701 $aWhelan$b Julie$0322651 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996206959203316 996 $aMicroenvironments in haemopoietic and lymphoid differentiation$91938556 997 $aUNISA