LEADER 01010nas 2200385-a 450 001 996206527903316 005 20220125001812.0 035 $a(DE-599)ZDB2178359-7 035 $a(OCoLC)370737040 035 $a(CKB)991042730887322 035 $a(CONSER)--2009247734 035 $a(EXLCZ)99991042730887322 100 $a20090605a19929999 --- - 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aHarvard science review 210 $aCambridge, MA $cHarvard Science Review 311 $a1062-7022 517 1 $aHSR 606 $aScience$vPeriodicals 606 $aScience 606 $aScience$2fast$3(OCoLC)fst01108176 608 $aPeriodical 608 $aPeriodicals.$2fast 608 $aPeriodicals.$2lcgft 615 0$aScience 615 2$aScience 615 7$aScience. 906 $aJOURNAL 912 $a996206527903316 996 $aHarvard science review$92034948 997 $aUNISA LEADER 05139nam 22008055 450 001 9910298282103321 005 20200629184537.0 010 $a94-017-9514-2 024 7 $a10.1007/978-94-017-9514-2 035 $a(CKB)3710000000316075 035 $a(EBL)1966771 035 $a(OCoLC)898213795 035 $a(SSID)ssj0001407876 035 $a(PQKBManifestationID)11876788 035 $a(PQKBTitleCode)TC0001407876 035 $a(PQKBWorkID)11410061 035 $a(PQKB)11609067 035 $a(DE-He213)978-94-017-9514-2 035 $a(MiAaPQ)EBC1966771 035 $a(PPN)183149076 035 $a(EXLCZ)993710000000316075 100 $a20141215d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSystems and Synthetic Biology /$fedited by Vikram Singh, Pawan K. Dhar 205 $a1st ed. 2015. 210 1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2015. 215 $a1 online resource (383 p.) 300 $aDescription based upon print version of record. 311 $a94-017-9513-4 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aIntroduction to Systems Biology -- Why Systems Biology Can Promote a New Way of Thinking -- Modelling Methodologies for Systems Biology -- In silico Identification of Eukaryotic Promoters -- Hill Equation in Modeling Transcriptional Regulation -- Molecular Modeling -- Complex Networks and Systems Biology -- Systems Biology of Infectious Diseases -- Systems Pharmacology and Pharmacogenomics for Drug Discovery and Development -- Switching Mechanism in the p53 Regulatory Network -- Systems Biology of Micro RNA -- A Brief Introduction to Synthetic Biology -- DNA Structure and Promoter Engineering -- Synchronous Sequential Computations with Biomolecular Reactions -- Designing Zinc Finger Proteins for Applications in Synthetic Biology -- Synthetic Biology for the Development of Biodrugs & Designer Crops and the Emerging Governance Issues -- Recent Advancement of Emerging Tools in Synthetic Biology for the Designing and Characterization of Genetic Circuits -- Metabolic Engineering of Microorganisms for Biosynthesis of Antibiotics -- DNA Origami: What, How and Where -- Making Synthetic Proteins from Non-coding DNA -- Engineering Biological Systems: A Brief Overview. 330 $aThis textbook has been conceptualized to provide a detailed description of the various aspects of Systems and Synthetic Biology, keeping the requirements of M.Sc. and Ph.D. students in mind. Also, it is hoped that this book will mentor young scientists who are willing to contribute to this area but do not know from where to begin. The book has been divided into two sections. The first section deals with the systems biology ? in terms of the foundational understanding, highlighting issues in biological complexity, methods of analysis and various aspects of modelling. The second section describes the engineering concepts and design strategies of biological systems ranging from simple DNA/RNA fragments, switches and oscillators, molecular pathways to a complete synthetic cell. Finally, the book offers expert opinions in legal, safety, security and social issues to present a well-balanced information both for students and scientists. 606 $aSystems biology 606 $aBiomedical engineering 606 $aBiological systems 606 $aBiochemical engineering 606 $aBiomathematics 606 $aBioinformatics 606 $aSystems Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L15010 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aSystems Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/P27050 606 $aBiochemical Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/C12029 606 $aMathematical and Computational Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/M31000 606 $aComputational Biology/Bioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/I23050 615 0$aSystems biology. 615 0$aBiomedical engineering. 615 0$aBiological systems. 615 0$aBiochemical engineering. 615 0$aBiomathematics. 615 0$aBioinformatics. 615 14$aSystems Biology. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aSystems Biology. 615 24$aBiochemical Engineering. 615 24$aMathematical and Computational Biology. 615 24$aComputational Biology/Bioinformatics. 676 $a570 676 $a570.285 676 $a570285 676 $a571.4 702 $aSingh$b Vikram$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDhar$b Pawan K$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298282103321 996 $aSystems and synthetic biology$92259029 997 $aUNINA