LEADER 03619nam 22006134a 450 001 996205342003316 005 20170815113010.0 010 $a1-280-74826-5 010 $a9786610748266 010 $a0-470-76148-2 010 $a0-470-98711-1 010 $a1-4051-7166-9 035 $a(CKB)1000000000341911 035 $a(EBL)284310 035 $a(OCoLC)476034208 035 $a(SSID)ssj0000123662 035 $a(PQKBManifestationID)11135856 035 $a(PQKBTitleCode)TC0000123662 035 $a(PQKBWorkID)10009681 035 $a(PQKB)11737022 035 $a(MiAaPQ)EBC284310 035 $a(PPN)162107900 035 $a(EXLCZ)991000000000341911 100 $a20060324d2005 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aClinical pediatric endocrinology$b[electronic resource] /$fedited by Charles G.D. Brook, Peter E. Clayton, Rosalind S. Brown ; foreword by Martin O. Savage 205 $a5th ed. 210 $aMalden, Mass. $cBlackwell Pub.$d2005 215 $a1 online resource (618 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-2655-8 320 $aIncludes bibliographical references. 327 $aClinical Pediatric Endocrinology; Contents; Contributors; Foreword; Preface to the fifth edition; Preface to the first edition; 1 Principles of hormone action; 2 Genetics,genomics,proteomics, and bioinformatics; 3 Measuring hormones,molecular and their clinical application; 4 Congenital disorders of the hypothalamic -pituitary axis; 5 Normal and disordered growth; 6 Genetic syndromes and dysmorphology; 7 Acquired abnormalities of the hypothalamic -pituitary axis leading to growth impairment; 8 Development of the reproductive systems; 9 Ambiguous genitalia; 10 Normal and abnormal puberty 327 $a11 Gynecology12 The thyroid and its disorders; 13 The parathyroid and disorders of calcium metabolism; 14 Disorders of bone metabolism; 15 The adrenal cortex and its disorders; 16 Polyglandular syndromes; 17 Disorders of water balance; 18 Endocrine programming and the fetal and early-life origins of adult disease; 19 Weight regulation and monogenic obesity; 20 Metabolic consequences of obesity and their management; 21 Diabetes mellitus; 22 Hypoglycemia; 23 Endocrine consequences of systemic disease:critical illness; 24 Consequences of radiotherapy, chemotherapy,and bone marrow transplant 327 $a25 Tests and normal values in pediatric endocrinologyAppendix; Index; Colour Plate section 330 $aThis new edition of the benchmark text on clinical pediatric endocrinology still remains at the forefront of world clinical opinion. Furthermore, the style, which has been the hallmark of the book for the last 20 years, has been maintained for this Fifth Edition. New features of this Fifth Edition include:Special new chapters cover the fetal origins of adult disease and theendocrine consequences and management of critical illness Now opens with a basic science section summarizing the mechanisms of hormone action, genomics, proteomics and the application 606 $aPediatric endocrinology 615 0$aPediatric endocrinology. 676 $a618.92/4 676 $a618.924 701 $aBrook$b C. G. D$g(Charles Groves Darville)$0855874 701 $aClayton$b Peter E$0873765 701 $aBrown$b Rosalind S$034241 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996205342003316 996 $aClinical pediatric endocrinology$91950629 997 $aUNISA