LEADER 04902nam 2200613Ia 450 001 996203974503316 005 20230721030949.0 010 $a1-281-32056-0 010 $a9786611320560 010 $a0-470-75597-0 010 $a0-470-75528-8 035 $a(CKB)1000000000406367 035 $a(EBL)351005 035 $a(SSID)ssj0000291575 035 $a(PQKBManifestationID)11245824 035 $a(PQKBTitleCode)TC0000291575 035 $a(PQKBWorkID)10249610 035 $a(PQKB)11491775 035 $a(MiAaPQ)EBC351005 035 $a(OCoLC)212125634 035 $a(MiFhGG)0SUJ 035 $a(EXLCZ)991000000000406367 100 $a20050427d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aChronic obstructive pulmonary disease$b[electronic resource] /$f[edited by] Robert A. Stockley ... [et al.] 210 $aMalden, MA ;$aOxford $cBlackwell Pub.$d2007 215 $a1 online resource (916 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-2289-7 320 $aIncludes bibliographical references and index. 327 $aChronic Obstructive Pulmonary Disease; Contents; Contributors; Preface; Section 1: Physiology; 1 Structure-Function Relationships: The Pathophysiology of Airflow Obstruction; 2 The Physiology of Breathlessness; 3 The Physiology of Muscle; 4 Exercise Limitations and Cardiopulmonary Exercise Testing in Copd; 5 Clinical Assessment of Control of Breathing; 6 Physiology and Pathobiology of the Lung Circulation; 7 Sleep In Patients With Copd; 8 The Physiology of Cough; 9 The Physiology of Gas Exchange; Section 2: COPD and allied conditions; 10 The Natural History of Copd; 11 Cystic Fibrosis 327 $a12 Bronchiectasis and Copd13 Obliterative Bronchiolitis; 14 Asthma; 15 Copd: Clinical Presentation and Evaluation; 16 Monitoring and Outcomes; Section 3: Host Defences and Inflammation; 17 Mucociliary Clearance; 18 Mucosal Immunity; 19 Copd and Pulmonary Surfactant; 20 The Macrophage and Its Role in the Pathogenesis of Copd; 21 Eosinophils and Copd; 22 Airway Epithelial Defence, Repair and Regeneration; 23 The Role of The Neutrophil In The Pathogenesis of Copd; 24 Lymphocytes; 25 Cytokines; 26 Leukotrienes In Copd: The Unexploited Potential 327 $a27 Cigarette Smoking, Emphysema and Lung Endothelium28 Mesenchymal Cells of the Lung; Section 4: Pathogenesis; 29 Lung Development; 30 Animal Models; 31 Proteinases and Copd; Colour Plate Section Falls Between Pp. 354 and 355; 32 Oxidants; 33 Cigarette Smoke-Induced Disease; 34 Copd and Air Pollution; 35 Viruses in Copd; 36 Bacteria; 37 Genetic Factors; 38 ?1-Antitrypsin Deficiency; 39 Body Weight and Systemic Effects; 40 Lung Connective Tissue; Section 5: Clinical Considerations and Complications; 41 Aerosols and Delivery Systems; 42 Gastro-Oesophageal Reflux; 43 Upper Airway Diseases 327 $a44 Acute Pulmonary Embolism45 Copd and Lung Cancer; 46 Infection Management and Airflow Obstruction; 47 Mechanical Ventilation For Exacerbation of Copd; 48 Comorbidity; Section 6: Current and Future Treatment; 49 Primary Care; 50 Pulmonary Rehabilitation; 51 Social Support; 52 Long-Term Invasive Mechanical Ventilation; 53 Smoking Cessation; 54 Oxygen Therapy in Copd; 55 Surgical Therapy For Copd; 56 Anticholinergics in Copd; 57 ?2-Agonists; 58 Corticosteroids; 59 Phosphodiesterase 4 Inhibitors In The Treatment of Copd; 60 Antibiotic Therapy in Patients With Copd; 61 Antioxidants 327 $a62 Mucolytics For Copd63 End-of-Life and Palliative Care for Patients With Copd; 64 Economic Burden of Copd; 65 Pharmacoepidemiology of Copd; 66 Social and Behavioural Impact of Copd ... Research Opportunities; 67 Guidelines; Section 7: Pharmacotherapy: Developing Therapies; 68 Protease Inhibitors; 69 Retinoids; 70 Chemokines in Copd; Index 330 $aThe only international clinical textbook for COPD - one of the top 5 causes of death and disability worldwideThe only COPD textbook to include the latest national and international guidelines and the newer therapeutic agents in COPD treatmentInternational team of contributors covers all aspects of COPD - from physiology and epidemiology to diagnosis and treatmentEverything the busy physician needs to understand, diagnose and treat the COPD patient: - Structure and physiology of the respiratory system- Clinical considerations and allied c 606 $aLungs$xDiseases, Obstructive 606 $aLungs$xDiseases 615 0$aLungs$xDiseases, Obstructive. 615 0$aLungs$xDiseases. 676 $a616.2/4 676 $a616.24 701 $aStockley$b Robert A$0953625 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996203974503316 996 $aChronic obstructive pulmonary disease$92156279 997 $aUNISA