LEADER 03742nam 2200649 a 450 001 996202090303316 005 20230315163923.0 010 $a1-280-78415-6 010 $a9786613694546 010 $a0-470-72092-1 010 $a0-470-71862-5 035 $a(CKB)1000000000688050 035 $a(EBL)703931 035 $a(OCoLC)797918527 035 $a(SSID)ssj0000715048 035 $a(PQKBManifestationID)11403972 035 $a(PQKBTitleCode)TC0000715048 035 $a(PQKBWorkID)10700676 035 $a(PQKB)10124599 035 $a(MiAaPQ)EBC703931 035 $a(Au-PeEL)EBL703931 035 $a(CaPaEBR)ebr10575605 035 $a(CaONFJC)MIL369454 035 $a(EXLCZ)991000000000688050 100 $a19850208d1985 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEnzymes in organic synthesis /$f[editors: Ruth Porter (organizer) and Sarah Clark 210 $aLondon $cPitman ;$aNewark, N.J. $cDistributed in North America by CIBA Pharmaceutical Co. (Medical Education Division)$d1985 215 $a1 online resource (258 pages) $cillustrations 225 1 $aCiba Foundation symposium ;$v111 300 $a"Symposium on Organic synthesis using enzymes, held at the Ciba Foundation, London, 15-17 May 1984"--Contents page. 311 0 $a0-470-66429-0 311 0 $a0-272-79785-5 320 $aIncludes bibliographical references and indexes. 327 $aEnzymes in organic synthesis; Contents; Chairman's introduction; An illustrative example of a synthetically useful enzyme: horse liver alcohol dehydrogenase; Discussion; Enzymic synthesis of labelled chiral substances; Discussion; Enzyme-controlled reactions giving alkanols of use in the synthesis of biologically active molecules; Discussion; Large-scale purification of enzymes; Discussion; Immobilized enzymes in organic synthesis; Discussion; General discussion I Synthesis of 5,6-dihydroxycyclohexa-l,3-die; Applications of cell-free enzymes in organic synthesis; Discussion 327 $aChiral products from non-pyridine nucleotide-dependent reductases and methods for NAD(P)H regeneration Discussion; Stereochemistry and synthetic applications of products of fermentation of a,p-unsaturated aromatic aldehydes by baker's yeast; Discussion; Extending the applicability of esterases of low enantioselectivity in asymmetric synthesis; Discussion; Microbial transformations of some monoterpenoids and sesquiterpenoids; Discussion; General discussion I1 Synthesis of tetrahydrofolate derivatives; Synthesis of optically active propylene oxides 327 $aCreation of novel chiral synthons with enzymes: application to enantioselective synthesis of antibiotics Discussion; Kinetics of trypsin catalysis in the industrial conversion of porcine insulin to human insulin; Discussion; Redesigning enzymes by site-directed mutagenesis; Discussion; The design of new enzyme active sites for the catalysis of specific chemical reactions; Discussion; Final general discussion NAD+ degradation by resting cells; Economic aspects; Applications of enzyme methodology; Index of contributors; Subject index 410 0$aCiba Foundation symposium ;$v111. 606 $aOrganic compounds$xSynthesis$vCongresses 606 $aEnzymes$vCongresses 615 0$aOrganic compounds$xSynthesis 615 0$aEnzymes 676 $a547/.2 701 $aPorter$b Ruth$064811 701 $aClark$b Sarah$0857128 712 02$aCiba Foundation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996202090303316 996 $aEnzymes in organic synthesis$92261364 997 $aUNISA