LEADER 03785nam 2200649 a 450 001 996201245303316 005 20230213211706.0 010 $a1-280-76861-4 010 $a9786613679383 010 $a0-470-71905-2 010 $a0-470-71652-5 035 $a(CKB)1000000000687592 035 $a(EBL)703751 035 $a(SSID)ssj0000715170 035 $a(PQKBManifestationID)11463731 035 $a(PQKBTitleCode)TC0000715170 035 $a(PQKBWorkID)10700059 035 $a(PQKB)10925434 035 $a(SSID)ssj0001034475 035 $a(PQKBManifestationID)11545098 035 $a(PQKBTitleCode)TC0001034475 035 $a(PQKBWorkID)11015808 035 $a(PQKB)21243831 035 $a(MiAaPQ)EBC703751 035 $a(OCoLC)264615365 035 $a(EXLCZ)991000000000687592 100 $a19851217d1957 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCiba Foundation Symposium on Drug Resistance in Micro-Organisms$b[electronic resource] $emechanisms of development. /$feditors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor 210 $aBoston $cLittle, Brown$d[1957] 215 $a1 online resource (384 p.) 225 1 $aCiba Foundation symposium 300 $aDescription based upon print version of record. 311 $a0-470-72248-7 320 $aIncludes bibliographical references and indexes. 327 $aDRUG RESISTANCE IN MICRO-ORGANISMS; CONTENTS; Chairman's opening remarks; Aspects of the problem of drug resistance in bacteria; Discussion; Indirect selection and origin of resistance; Discussion; Genetic aspects of drug resistance; Discussion; Inheritance in single bacterial cells; Discussion; Penicillin-induced resistance to penicillin in cultures of Bacillus cereus; Discussion; Directed hereditary changes of fermentative properties of yeast by a specific substrate; Discussion; Multiple mechanisms of acquired drug resistance; Discussion 327 $aPhysiological (phenotypic) mechanisms responsible for drug resistanceDiscussion; Genetic and metabolic mechanisms underlying multiple levels of sulphonamide resistance in pneumococci; Discussion; The phenotypic expression of genes determining various types of drug resistance following their inheritance by sensitive bacteria; Discussion; Specific polyhydroxy compounds as cofactors of enzymic adaptation and its inheritance; Discussion; Development of resistance to streptomycin in Serratia marcescens; Discussion 327 $aDistribution of drug-resistant individuals in cultures of Mycobacterium tuberculosisDiscussion; Physiological adaptation of bacteria to antibiotics; Discussion; Drug resistance of staphylococci with special reference to penicillinase production; Discussion; On the identification of genetic and non-genetic variation in bacteria; Discussion; The reactions of the mutagenic alkylating agents with proteins and nucleic acids; Discussion; Genetics of two different mechanisms of resistance to colicins: resistance by loss of specific receptors and im- munity by transfer of colicinogenic factors 327 $aDiscussionGeneral Discussion; Chairman's closing remarks 410 0$aCiba Foundation symposium. 606 $aDrug resistance in microorganisms$vCongresses 615 0$aDrug resistance in microorganisms 676 $a600 701 $aWolstenholme$b G. E. W$g(Gordon Ethelbert Ward)$063039 701 $aO'Connor$b Cecilia M$g(Cecilia Mary),$f1927-$0207754 712 02$aCiba Foundation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996201245303316 996 $aCiba Foundation Symposium on Drug Resistance in Micro-Organisms$93004829 997 $aUNISA