LEADER 01525nam2 2200373 i 450 001 SUN0060173 005 20090907120000.0 010 $a88-02-05661-7 020 $aIT$b2002 5695 100 $a20070702d2001 |0itac50 ba 101 $aita$aGRC 102 $aIT 105 $a|||| ||||| 200 1 $aˆ[1]: ‰Libri 13.-17.$ele guerre civili$fdi Appiano$ga cura di Emilio Gabba e Domenico Magnino 205 $aTorino : UTET$bc2001 210 $d920 p., [6] c. di tav. : ill 215 $aTesto greco a fronte. 410 1$1001SUN0034748$12001 $aClassici greci$1210 $aTorino$cUtet. 461 1$1001SUN0060197$12001 $aStoria romana$fdi Appiano$v1$1210 $aTorino$cUTET$d2001-$1215 $av.$d24 cm. 620 $dTorino$3SUNL000001 676 $a937.05$v21 700 0$aAppianus$3SUNV047535$0473209 702 1$aGabba$b, Emilio$3SUNV008917 702 1$aMagnino$b, Domenico$3SUNV029441 712 $aUTET$3SUNV000072$4650 790 0$aAppianus Alexandrinus$zAppianus$3SUNV047536 790 0$aAppiano di Alessandria$zAppianus$3SUNV047537 790 0$aAppiano$zAppianus$3SUNV047538 801 $aIT$bSOL$c20181109$gRICA 912 $aSUN0060173 950 $aUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI LETTERE E BENI CULTURALI$d07 CONS Xd 8 App $e07 12107 995 $aUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI LETTERE E BENI CULTURALI$bIT-CE0103$h12107$kCONS Xd 8 App$oc$qa 996 $aLibri 13.-17$9886529 997 $aUNICAMPANIA LEADER 05263nam 2200625 450 001 996197616303316 005 20230109005118.0 010 $a1-281-75881-7 010 $a9786611758813 010 $a3-527-61593-8 010 $a3-527-61592-X 035 $a(CKB)1000000000376036 035 $a(EBL)481567 035 $a(SSID)ssj0000097791 035 $a(PQKBManifestationID)11116716 035 $a(PQKBTitleCode)TC0000097791 035 $a(PQKBWorkID)10120693 035 $a(PQKB)10682907 035 $a(MiAaPQ)EBC481567 035 $a(MiAaPQ)EBC7076267 035 $a(Au-PeEL)EBL7076267 035 $a(OCoLC)184983909 035 $a(EXLCZ)991000000000376036 100 $a20230109d1994 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAdvanced organic chemistry of nucleic acids /$fZ. Shabarova, A. Bogdanov, translated by Vladimir Vopyan 210 1$aWeinheim, Germany ;$aNew York, New York :$cVCH,$d[1994] 210 4$d©1994 215 $a1 online resource (606 p.) 300 $aDescription based upon print version of record. 311 $a3-527-29021-4 320 $aIncludes bibliographical references and index. 327 $aAdvanced Organic Chemistry of Nucleic Acids; Contents; 1 Structure of Nucleosides; 1.1 Introduction; 1.2 Pyrimidine and Purine Bases; 1.2.1 Pyrimidines; 1.2.2 Purines; 1.2.3 Nomenclature of Pyrimidines and Purines; 1.2.4 Abbreviations; 1.3 Carbohydrate Moieties of Nucleosides; 1.4 Bonding Between Carbohydrate Moiety and Heterocyclic Base; 1.4.1 Purine Nucleosides; 1.4.2 Pyrimidine Nucleosides; 1.5 Size of the Oxide Ring in the Sugar; 1.6 Configuration of the Glycoside (Anomeric) Center; 1.7 Nomenclature and Abridged Formulas of Nucleosides; 1.8 Minor Nucleosides; 1.9 Pseudouridine 327 $a1.10 Nucleoside Antibiotics1.10.1 Purine Nucleosides; 1.10.2 Pyrimidine Nucleosides; 1.11 Other Nucleosides; References; 2 Properties of Nucleosides; 2.1 Heterocyclic Bases; 2.1.1 General Concepts; 2.1.2 Tautomerism; 2.1.3 Reactions with Electrophilic Reagents; 2.1.4 Reactions with Nucleophilic Reagents; 2.1.5 Addition Reactions; 2.1.6 Reactions Involving Exocyclic Amino Groups; 2.2 Reactions at the Carbohydrate Moiety; 2.2.1 Substitution for Hydrogen Atoms in Hydroxyl Groups; 2.2.2 Oxidation; 2.3 Reactions Involving Heterocyclic Bases and the Carbohydrate Moiety 327 $a2.4 Stability of N-Glycosidic Bonds2.4.1 Effect of the Heterocyclic Base Species; 2.4.2 Effect of Substituents in the Carbohydrate Moiety; 2.4.3 Mechanism of Hydrolysis of N-Glycosidic Bonds; 2.5 Properties of Pseudouridine; References; 3 Structure of Nucleotides; 3.1 Introduction; 3.2 Nomenclature and Isomerism; 3.3 Structure of Nucleotides; 3.3.1 Nucleoside 5'-Phosphates; 3.3.2 Nucleoside 3'- and 2'-Phosphates; 3.3.3 Nucleoside Cyclic Phosphates; 3.3.4 Nucleoside 3'(2').5'-Diphosphates; 3.4 General Comments Regarding the Structure of Monomer Units in Nucleic Acids; References 327 $a4 Properties of Nucleotides4.1 Acid-Base Behavior; 4.1.1 Ionization of Bases; 4.1.2 Ionization of Hydroxyl Groups in Pentose; 4.1.3 Ionization of the Phosphate Group; 4.2 Formation of Derivatives with Metals; 4.3 Reactions at Heterocyclic Bases and Pentose; 4.4 Some Properties of the Phosphate Group (General Concepts); 4.4.1 Structure of the Phosphate Group and the Mechanism of Nucleophilic Substitution at the Phosphorus Atom; 4.4.2 Catalysis of Nucleophilic Substitution at the Phosphorus Atom; 4.4.3 Hydrolysis of Alkyl Phosphates; 4.4.4 Cyclic Phosphates; 4.4.5 B-Elimination Reactions 327 $a4.5 Reactions of Nucleotides Involving the Phosphate Group4.5.1 Chemical and Enzymatic Dephosphorylation; 4.5.2 Migration of the Phosphate Group; 4.5.3 Alkylation of the Phosphate Group; 4.5.4 Activation of the Phosphate Group in Nucleotides . Synthesis of Some Derivatives with Respect to the Phosphate Group; 4.5.5 Acylation of the Phosphate Group; 4.6 Properties of Nucleotide Derivatives with Substituents in the Phosphate Group; 4.6.1 Nucleoside Cyclic Phosphates; 4.6.2 Alkyl Esters of Nucleotides; 4.6.3 Mixed Anhydrides of Nucleotides; 4.6.4 Amides of Nucleotides 327 $a4.7 Hydrolysis of N-Glycosidic Bonds 330 $aSequencing, cloning, transcription - these are but a few key techniques behind the current breathtaking advances in molecular biology and biochemistry. As these methods continuosly diversify, biochemists need a sound chemical understanding to keep the pace. Chemists beginning working in the molecular biology lab need an introduction to this field from their point of view. This book serves both: it describes most of the known chemical reactions of nucleosides, nucleotides, and nucleic acids in sufficient detail to provide the desired background, and additionally, the fundamental relations betwe 606 $aNucleic acids 615 0$aNucleic acids. 676 $a574.87328 700 $aShabarova$b Z$g(Zoe),$0902272 702 $aBogdanov$b A$g(Alexey), 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a996197616303316 996 $aAdvanced organic chemistry of nucleic acids$93062366 997 $aUNISA