LEADER 01114nam--2200385---450- 001 990003665550203316 005 20120528143721.0 010 $a9788814162817 035 $a000366555 035 $aUSA01000366555 035 $a(ALEPH)000366555USA01 035 $a000366555 100 $a20120528d2012----km-y0itay50------ba 101 $aita 102 $aIT 105 $a||||||||001yy 200 1 $aStudi sui principi del diritto amministrativo$fFrancesco Astone ... [et al.]$ga cura di Mauro Renna, Fabio Saitta 210 $aMilano$cGIuffrè$d2012 215 $aXVI, 576 p.$d24 cm 410 0$12001 454 1$12001 461 1$1001-------$12001 606 0 $aDiritto amministrativo$xRaccolte di saggi$yItalia 676 $a342.4506 702 1$aASTONE,$bFrancesco 702 $aRENNA,$bMauro 702 2 $aSAITTA,$bFabio 801 0$aIT$bsalbc$gISBD 912 $a990003665550203316 951 $a342.4506 AST$bDISES 959 $aBK 969 $aDISES 979 $aMORRIELLO$b10$c20120528$lUSA01$h1437 996 $aStudi sui principi del diritto amministrativo$9846693 997 $aUNISA LEADER 02878nam 2200421z- 450 001 9910261145903321 005 20210212 035 $a(CKB)4100000002484633 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/58232 035 $a(oapen)doab58232 035 $a(EXLCZ)994100000002484633 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aRepetitive Structures in Biological Sequences: Algorithms and Applications 210 $cFrontiers Media SA$d2016 215 $a1 online resource (93 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-018-X 330 $aRepetitive structures in biological sequences are emerging as an active focus of research and the unifying concept of "repeatome" (the ensemble of knowledge associated with repeating structures in genomic/proteomic sequences) has been recently proposed in order to highlight several converging trends. One main trend is the ongoing discovery that genomic repetitions are linked to many biological significant events and functions. Diseases (e.g. Huntington's disease) have been causally linked with abnormal expansion of certain repeating sequences in the human genome. Deletions or multiple copy duplications of genes (Copy Number Variations) are important in the aetiology of cancer, Alzheimer, and Parkinson diseases. A second converging trend has been the emergence of many different models and algorithms for detecting non-obvious repeating patterns in strings with applications to in genomic data. Borrowing methodologies from combinatorial pattern, matching, string algorithms, data structures, data mining and machine learning these new approaches break the limitations of the current approaches and offer a new way to design better trans-disciplinary research. The articles collected in this book provides a glance into the rich emerging area of repeatome research, addressing some of its pressing challenges. We believe that these contributions are valuable resources for repeatome research and will stimulate further research from bioinformatic, statistical, and biological points of view. 517 $aRepetitive Structures in Biological Sequences 606 $aHistory of engineering and technology$2bicssc 610 $aAlgorithms 610 $anext generation sequencing 610 $aRepetitive structures 610 $atandem repeats 610 $atransposable elements 615 7$aHistory of engineering and technology 700 $aMarco Pellegrini$4auth$0500114 702 $aAlberto Magi$4auth 702 $aCostas S. Iliopoulos$4auth 906 $aBOOK 912 $a9910261145903321 996 $aRepetitive Structures in Biological Sequences: Algorithms and Applications$93020256 997 $aUNINA