LEADER 00920nas--2200325---4500 001 990003626710203316 005 20120221084849.0 011 $a1125-114X 035 $a000362671 035 $aUSA01000362671 035 $a(ALEPH)000362671USA01 035 $a000362671 100 $a20120221a----9999km-y0itay50------ba 101 0 $aita 102 $aIT 110 $aaaazz--|||| 200 1 $aRiza scienze$emensile di scienze per l'uomo 207 1$aA. 1, n. 1 (set. 1983)- 210 $aMilano$cEdizioni Riza srl 215 $avolumi$d24 cm 326 $aMensile 606 0 $aMedicina$xStoria$xPeriodici 676 $a610.9 801 0$aIT$bsalbc$gISBD 912 $a990003626710203316 958 $aUMA$bFondo$cn.24 (1989); n.26 (1989)-n.27 (1989); n.32 (1989); n.37 (1990); n.39 (1990); 959 $aSE 979 $aVITTORIANA$b90$c20120221$lUSA01$h0848 996 $aRiza scienze$91138396 997 $aUNISA LEADER 02487nam 2200373 450 001 9910674386903321 005 20230702164033.0 035 $a(CKB)5700000000300394 035 $a(NjHacI)995700000000300394 035 $a(EXLCZ)995700000000300394 100 $a20230702d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aClear Cell Renal Cell Carcinoma 2021-2022 /$fClaudia Manini and Jose? I. Lo?pez 210 1$aBasel, Switzerland :$cMDPI - Multidisciplinary Digital Publishing Institute,$d2022. 215 $a1 online resource (342 pages) 311 $a3-0365-5517-X 330 $aClear cell renal cell carcinoma is currently one of the most interesting areas of study in oncology. Despite the advances made in this field, this tumor continues to be a health problem of major concern in Western societies, seriously affecting public health services. Several characteristics of this tumor make it an exciting meeting point for translational collaboration between clinicians and basic researchers. Clear cell renal cell carcinoma is a paradigmatic example of inter- and intra-tumor heterogeneity from morphological, immunohistochemical, and molecular viewpoints. This tumor is also a good example to investigate the complexity of tumor/tumor and tumor/environment relationships from an ecological perspective. A deeper identification of the varied internal tumor self-organization through the specialization of cell clones and subclones as local invaders and metastasizers, on one hand, and the interactions of specific subsets of tumor cells with the local host microenvironment, on the other, will significantly enrich our knowledge of this neoplasm. Clear cell renal cell carcinoma is also a paradigmatic test bench for antiangiogenic and immune checkpoint blockage therapies. The refinement of these therapeutic tools administered alone or in combination is a hot issue in oncology, and several international trials are underway. 606 $aBiomedical materials 606 $aCarcinoma, Renal Cell 615 0$aBiomedical materials. 615 0$aCarcinoma, Renal Cell. 676 $a616.99461 700 $aManini$b Claudia$01369297 702 $aLo?pez$b Jose? I. 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910674386903321 996 $aClear Cell Renal Cell Carcinoma 2021-2022$93395431 997 $aUNINA LEADER 01333oam 2200277z- 450 001 9910158892603321 010 $a1-78428-184-0 035 $a(CKB)3710000001011771 035 $a(VLeBooks)9781784281847 035 $a(EXLCZ)993710000001011771 100 $a20190224c2016uuuu -u- - 101 0 $aeng 200 $aDictators in cartoons 210 $cArcturus 215 $a1 online resource (1 p.) 330 $aWhat is it that makes dictators fear cartoonists? The answer is that they can't stand to be ridiculed. And they don't help their cause much by so obviously enjoying the trappings of power, appearing in public with a retinue of bodyguards, a fleet of limousines and rows of medals across their chests topped off with over-sized sunglasses. Cartoonists may not be able to topple tyrants or change the course of history, but they can lessen the climate of fear and bring courage to the victims of state bullying with their subversive drawings. Laughter is the last thing dictators want to hear, especially when they are the subject of it. 606 $aDictators 606 $aHistory, Modern 615 0$aDictators. 615 0$aHistory, Modern. 676 $a741.569 700 $aTony Husband$01745188 906 $aBOOK 912 $a9910158892603321 996 $aDictators in cartoons$94175688 997 $aUNINA