LEADER 01325nam--2200397---450- 001 990003412320203316 005 20100611155431.0 010 $a978-88-95154-75-6 035 $a000341232 035 $aUSA01000341232 035 $a(ALEPH)000341232USA01 035 $a000341232 100 $a20100611h2009----km-y0itay50------ba 101 $aita 102 $aIT 105 $a||||||||001yy 200 1 $a<> integrazione scolastica degli alunni con bisogni educativi speciali$fAlisia Rosa Arturi$gprefazione di Achille M. Notti 210 $aSalerno$cEdisud$d2009 215 $a123 p.$d24 cm 225 2 $aProcessi formativi e valutazione$v1 410 0$12001$aProcessi formativi e valutazione$v1 606 0 $aAlunni$xIntegrazione scolastica$2BNCF 676 $a371.91 700 1$aARTURI,$bAlisia Rosa$0607942 702 1$aNOTTI,$bAchille M. 801 0$aIT$bsalbc$gISBD 912 $a990003412320203316 951 $aII.4. 3893$b226371 L.M.$cII.4.$d00259450 951 $aII.4. 3893 a$b226370 L.M.$cII.4.$d00259452 959 $aBK 969 $aUMA 979 $aPAOLA$b90$c20100611$lUSA01$h1552 979 $aPAOLA$b90$c20100611$lUSA01$h1554 979 $aPAOLA$b90$c20100611$lUSA01$h1554 996 $aIntegrazione scolastica degli alunni con bisogni educativi speciali$91125822 997 $aUNISA LEADER 04938nam 22005415 450 001 9910253863103321 005 20220304161026.0 010 $a3-319-15889-9 024 7 $a10.1007/978-3-319-15889-1 035 $a(CKB)3710000000616241 035 $a(EBL)4438938 035 $a(SSID)ssj0001653914 035 $a(PQKBManifestationID)16433959 035 $a(PQKBTitleCode)TC0001653914 035 $a(PQKBWorkID)14982212 035 $a(PQKB)10922369 035 $a(DE-He213)978-3-319-15889-1 035 $a(MiAaPQ)EBC4438938 035 $a(PPN)192773704 035 $a(EXLCZ)993710000000616241 100 $a20160304d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aTherapeutic Potentials of Curcumin for Alzheimer Disease /$fby Akhlaq A Farooqui 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (418 p.) 300 $aIncludes index. 311 0 $a3-319-15888-0 327 $aPreface -- Effect of long term consumption of high calorie diet and calorie restriction on human health -- Neurochemical effects of long term consumption of high fat diet -- Neurochemical effects of long term consumption of simple carbohydrates -- Effects of long term consumption of animal proteins in the high calorie diet -- Effect of soft drink consumption on human health -- Contribution of salt in inducing biochemical changes in the brain -- Importance and roles of fiber in the diet -- Effects of the high calorie diet on the development of chronic visceral disease -- Effects of long term consumption of high calorie diet on neurological disorders -- Perspective and direction for future research: modification of high calorie diet needed for optimal health of human visceral and brain tissues -- Index. 330 $aCurcumin is a yellow?orange pigment obtained from the plant Curcuma longa. The powdered rhizome of this plant, called turmeric, is a common ingredient in curry powders and has a long history of use in traditional Asian medicine. Thus, curcumin has been used extensively in Ayurvedic medicine (Indian system of medicine) and Chinese traditional medicine for centuries as a antinociceptive, antiinflammatory, and antishock agent to relieve pain and inflammation. Epidemiological studies have revealed that in India, where dietary curcumin is consumed daily in the form of curry than in the United States, the morbidity rate attributed to Alzheimer disease (AD) for Indian elders (70?79 years old) is 4.4 times lower compared to the same age group of Americans. Furthermore, elderly healthy individuals who consume curry more frequently show better cognitive performance than senior who do not consume curry. Curcumin has been extensively investigated for treating AD over decades in animal model of AD, where curcumin crosses blood brain barrier and neural cell membranes and mediates its antioxidant, antiinflammatory, antiamyloidogenic , antiangiogenic, antiproliferative, antiapoptotic, metal chelating effects leading to retardation of signal transduction pathways associated with oxidative stress and neuroinflammation. Thus, curcumin fulfills the characteristics for an ideal neuroprotective agent for AD with its low toxicity, affordability, and easy accessibility. However, poor bioavailability of curcumin is the major hurdle for its more widespread use in animals and humans. The bioavailability of curcumin can be increased by encapsulation of curcumin into liposomes, cyclodextrin, curcumin conjugate with PLGA, complexation with phospholipids, and synthesis of curcumin analogs. This monograph is the first to describe neurochemical potentials of curcumin for the treatment of AD. This monograph presents readers with cutting edge and comprehensive information on the effect of curcumin on visceral organs and brain. It is hoped that this monograph will be useful to postgraduate students, faculty, research scientists, nutritionists, and physicians, who are curious signal transduction processes associated with antioxidant, antiinflammatory, antiamyloidogenic , antiangiogenic, antiproliferative, and antiapoptotic effects of curcumin on the brain. . 606 $aNeurochemistry 606 $aFood$xBiotechnology 606 $aNeurochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/B18010 606 $aFood Science$3https://scigraph.springernature.com/ontologies/product-market-codes/C15001 615 0$aNeurochemistry. 615 0$aFood$xBiotechnology. 615 14$aNeurochemistry. 615 24$aFood Science. 676 $a610 700 $aFarooqui$b Akhlaq A.$4aut$4http://id.loc.gov/vocabulary/relators/aut$0891929 906 $aBOOK 912 $a9910253863103321 996 $aTherapeutic Potentials of Curcumin for Alzheimer Disease$92524219 997 $aUNINA