LEADER 01054nam--2200361---450- 001 990003398830203316 005 20100513141002.0 010 $a978-987-629-016-6 035 $a000339883 035 $aUSA01000339883 035 $a(ALEPH)000339883USA01 035 $a000339883 100 $a20100513d2007----km-y0itay50------ba 101 $aspa 102 $aAR 105 $a||||||||001yy 200 1 $a<> inmigracion fascista en la Argentina$fpor Federica Bertagna 210 $aBuenos Aires$cSiglo 21.$d2007 215 $a296 p.$d21 cm 225 2 $aHistorya y cultura 410 0$12001$aHistorya y cultura 454 0$12001 606 0 $aFascisti italiani$yArgentina$z1945-1955$2BNCF 676 $a945.0924092 700 1$aBERTAGNA,$bFederica$0314881 801 0$aIT$bsalbc$gISBD 912 $a990003398830203316 951 $aX.3.B. 5639$b2973 L.G.$cX.3.B.$d00258303 959 $aBK 969 $aUMA 979 $aALESSANDRA$b90$c20100513$lUSA01$h1410 996 $aInmigracion fascista en la Argentina$91126748 997 $aUNISA LEADER 03948nam 2200865z- 450 001 9910557297603321 005 20210501 035 $a(CKB)5400000000041063 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69163 035 $a(oapen)doab69163 035 $a(EXLCZ)995400000000041063 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aBotulinum Toxin Treatment for Pain and Inflammation in Functional Urological Disorders 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (196 p.) 311 08$a3-03936-670-X 311 08$a3-03936-671-8 330 $aThe botulinum toxin has been widely applied in the treatment of functional urological diseases, such as overactive bladder, neurogenic detrusor overactivity, interstitial cystitis, and chronic pelvic pain syndrome. Evidence has shown that the botulinum toxin not only affects the release of neuropeptides from motor nerve endings, but also connects sensory nerves to the central nervous system. Inflammation in the central nervous system can be reduced after botulinum toxin treatment. The scope of therapeutic targets involves detrusor overactivity, sensory disorders, bladder pain and pelvic pain, and inflammatory disorders of the bladder, prostate, and bladder outlet. Although the actual pathophysiological mechanism of the action of the botulinum toxin has not been completely demonstrated, an anti-inflammation effect might be the predominant therapeutic mechanism for functional urological disorders such as an overactive bladder, bladder hypersensitivity, interstitial cystitis, chronic pelvic pain syndrome, chronic prostatitis, and lower urinary tract symptoms/benign prostatic hyperplasia. This Special Issue of Toxins covers the therapeutic potentials of the botulinum toxin on lower urinary tract dysfunctions, with emphasis on the mechanism of pharmacological action and clinical effects. 606 $aMedicine and Nursing$2bicssc 610 $aantimuscarinics 610 $abenign prostatic hyperplasia 610 $abladder 610 $abladder pain 610 $abotulinum toxin 610 $aBotulinum toxin 610 $abotulinum toxin A 610 $achronic pelvic pain syndrome 610 $achronic prostatitis 610 $adiabetes mellitus 610 $adrug delivery 610 $afunctional urological disorders 610 $afunctional urology disorder 610 $ahuman 610 $ahydrodistention 610 $ainflammation 610 $ainterstitial cystitis 610 $alower urinary tract symptoms 610 $amaximal bladder capacity 610 $amid-urethral sling 610 $amolecular mechanism 610 $anetwork meta-analysis 610 $aneurogenic detrusor overactivity 610 $aonabotulinumtoxinA 610 $aOnabotulinumtoxinA 610 $aoveractive bladder 610 $apain 610 $apainful bladder syndrome 610 $apathophysiology 610 $apelvic pain 610 $aperipheral tibial nerve stimulation 610 $apredictor 610 $aprostatitis 610 $asacral neuromodulation 610 $asensation 610 $atherapeutic outcome 610 $atherapy 610 $atreatment 610 $aurethra 610 $aurethral sphincter 610 $aurethral sphincter dysfunction 610 $aurinary incontinence 610 $aurodynamics 610 $avoiding 615 7$aMedicine and Nursing 700 $aKuo$b Hann-Chorng$4edt$01281276 702 $aKuo$b Hann-Chorng$4oth 906 $aBOOK 912 $a9910557297603321 996 $aBotulinum Toxin Treatment for Pain and Inflammation in Functional Urological Disorders$93018456 997 $aUNINA