LEADER 00941nam--2200337---450- 001 990001656800203316 005 20050623134037.0 035 $a000165680 035 $aUSA01000165680 035 $a(ALEPH)000165680USA01 035 $a000165680 100 $a20040512d19651964km-y0itay0103----ba 101 0 $aeng 102 $aUS 105 $a||||||||001yy 200 1 $aMorals and Law$ethe growth of Aristoteles legal theory$fby Max Hamburger 210 $aNew York$cBiblo and Tannen$d1965 215 $aXXII, 191 p.$d23 cm 410 0$12001 454 1$12001 461 1$1001-------$12001 700 1$aHAMBURGER,$bMax$0260051 801 0$aIT$bsalbc$gISBD 912 $a990001656800203316 951 $aII.1.A. 481(IV C 1647)$b36335 L.M.$cIV C 959 $aBK 969 $aUMA 979 $aSIAV6$b10$c20040512$lUSA01$h1914 979 $aCOPAT3$b90$c20050623$lUSA01$h1340 996 $aMorals and law$9705780 997 $aUNISA LEADER 01239nam a2200373 i 4500 001 991001079249707536 005 20020507110955.0 008 970308s1972 uk ||| | eng 035 $ab10170704-39ule_inst 035 $aLE00641793$9ExL 040 $aDip.to Fisica$bita 084 $a53(021) 084 $a53.1.32 084 $a53.1.51 084 $a53.2.2 084 $a530 084 $aQC21.2 100 1 $aLandau, Lev Davidovic$040436 245 10$aMechanics and electrodynamics /$cby L.D. Landau and E.M. Lifshitz ; translated from the russian by J.B. Sykes and M. Hamermesh 260 $aOxford :$bPergamon,$c1972 300 $axiii, 282 p. ;$c22 cm. 440 2$aA shorter course of theoretical physics ;$v1 650 4$aMechanics 650 4$aPhysics 650 4$aQuantum theory 700 1 $aLifsits, Evgenij Mikhailovich 700 1 $aSykes, J.B. 700 1 $aHamermesh, Morton 907 $a.b10170704$b21-09-06$c27-06-02 912 $a991001079249707536 945 $aLE006 53(021) LAN$g1$i2006000030519$lle006$o-$pE0.00$q-$rl$s- $t0$u2$v0$w2$x0$y.i1020894x$z27-06-02 996 $aMechanics and electrodynamics$9189855 997 $aUNISALENTO 998 $ale006$b01-01-97$cm$da $e-$feng$guk $h0$i1 LEADER 06166nam 2200421z- 450 001 9910346737003321 005 20210211 035 $a(CKB)4920000000094344 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54425 035 $a(oapen)doab54425 035 $a(EXLCZ)994920000000094344 100 $a20202102d2018 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNeonatal and Pediatric Cerebro-Cardiopulmonary Resuscitation 210 $cFrontiers Media SA$d2018 215 $a1 online resource (112 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-659-5 330 $aPediatric resuscitation medicine has witnessed significant advances with improved understanding of the pathophysiology of cardiac arrest and resuscitation. Multiple mechanisms of neurological injury have been identified, outlining potential avenues for neuroprotection following cardiac arrest. Resuscitation science exists at multiple levels of analysis, from biomechanics of chest compressions to implementation of best training procedures in real time, from epidemiology of cardiac arrest survival to molecular mechanisms of cellular injury due to ischemia and reperfusion. What next steps in research and in clinical practice will ensure the best possible neurologic outcome among children who survive cardiac arrest? How can we leverage novel technologies in neuroimaging, nanomaterials, drug delivery, biomarker-based risk stratification and next generation sequencing, among others, to resuscitate and to protect the Central Nervous System (CNS)? How can we improve clinical trial design and data analyses to maintain a robust clinical research infrastructure and to ensure validity and applicability? These are just some of the questions will addressed in this Research Topic. Using evidence-based algorithms and public health approaches to disseminate them, the last decade has seen a paradigm shift in pediatric resuscitation with significantly improved survival from pediatric cardiac arrests. However, neurologic outcome in survivors remains far from optimal. High quality CPR is increasingly recognized as a key factor for improving neurologic outcomes. Advanced technologies allow monitoring the quality of CPR and just-in-time feedback to improve the quality of CPR. Further research is needed to evaluate impact of these technologies on neurologic outcome. The recent American Heart Association CPR guidelines emphasis on Circulation-Airway-Breathing (CAB) approach to CPR needs a careful evaluation in children, in whom timely airway and breathing support are as important as circulation. The growing controversy regarding use of epinephrine, and alternative routes of administration of epinephrine during CPR, warrants further evaluation in the setting of pediatric CPR. Improved outcome of hemodynamic goal-directed CPR over standard CPR in animal models of cardiac arrest has initiated interest in physiology-based CPR, especially in the in-hospital cardiac arrest. Basic and applied-science research have become relevant for specific subpopulations of pediatric cardiac arrest victims and circumstances (e.g., ventricular fibrillation, neonates, congenital heart disease, extracorporeal cardiopulmonary resuscitation). Just-in-time and just-in-place simulation training, which have evolved as training strategies to improve quality of CPR, are being evaluated for outcomes. The concept of just-in-time and just-in-place coaching of CPR providers on high quality CPR is a novel concept which has emerged recently and remains unstudied. Whilst there have been significant advances in newborn stabilization over the last decade many questions remain unanswered. These include the role of delayed cord clamping in preterm infants and term newborns requiring resuscitation, the role of sustained inflations as a method of respiratory support and the role of epinephrine and volume administration in neonatal resuscitation. Novel methods of assessment including the use of end tidal CO2 monitoring, respiratory function monitoring and near infrared spectroscopy warrant further evaluation. The use of transitioning animal models that accurately replicate the newborn circulation with patent fetal shunts are emerging but more assessments in these are required to better establish CPR strategies in newborn infants. Newborn resuscitation training programs have resulted in a reduction in neonatal mortality in the developing world, but key questions remain around the frequency of training, team training methods and the role of simulation training. Post resuscitation interventions, in particular therapeutic hypothermia, has resulted in significant improvements in long-term outcome and there is now a growing interest in adjunct therapies, such as use of melatonin, erythropoietin, or other neuroprotective molecules to improve therapeutic benefits of cooling. Therapeutic hypothermia did not provide any higher benefit than normothermia in children following out of hospital cardiac arrest, although three is considerable debate in the community whether 14% probability of observing a similar outcome if the study were repeated a 100 times applies to an individual child in the PICU. Exciting research is occurring in unraveling connection between inflammation, immune dysregulation and neuroinjury. This will further support research on the use of anti-inflammatory agents and immunomodulators for neuroprotection after cardiac arrest and birth asphyxia. 606 $aMedicine and Nursing$2bicssc 610 $acardio-pulmonary resuscitation 610 $acerebral cortex 610 $aneonatal asphyxia 610 $aneonatology 610 $atherapeutic hypothermia 615 7$aMedicine and Nursing 700 $aUtpal Bhalala$4auth$01296317 702 $aMichael Shoykhet$4auth 702 $aGraeme Polglase$4auth 702 $aEugene Dempsey$4auth 906 $aBOOK 912 $a9910346737003321 996 $aNeonatal and Pediatric Cerebro-Cardiopulmonary Resuscitation$93023994 997 $aUNINA