LEADER 01574nam--2200433---450- 001 990001172350203316 005 20050607090647.0 010 $a88-343-0780-1 035 $a000117235 035 $aUSA01000117235 035 $a(ALEPH)000117235USA01 035 $a000117235 100 $a20030911d2002----km-y0enga50------ba 101 0 $aita 102 $aIT 105 $ay|||z|||001yy 200 1 $aProblemi fondamentali dell'ontologia analitica$fEdmund Runggaldier, Christian Kanzian$ga cura di Sergio Galvan 210 $aMilano$cVita e Pensiero$d2002 215 $aXIII,240 p.$d24 cm 225 2 $aPubblicazioni del Centro di ricerche di metafisica$iSezione di metafisica e storia della metafisica$v23 410 0$12001$aPubblicazioni del Centro di ricerche di metafisica$iSezione di metafisica e storia della metafisica 454 1$12001$aGrundprobleme der analytischen Ontologie$952837 606 0 $aOntologia 676 $a111 700 1$aRUNGGALDIER,$bEdmund$0555523 701 1$aKANZIAN,$bChristian$0555524 702 1$aGALVAN,$bSergio 801 0$aIT$bSalbc$cISBD 912 $a990001172350203316 951 $aII.1 Coll.64/ 2(IV A COLL. 268 23)$b168091 L.M.$cIV A$d00086577 959 $aBK 969 $aUMA 979 $aMARIA$b10$c20030911$lUSA01$h1150 979 $aALESSANDRA$b90$c20031031$lUSA01$h1209 979 $aALESSANDRA$b90$c20031031$lUSA01$h1210 979 $aPATRY$b90$c20040406$lUSA01$h1724 979 $aCOPAT5$b90$c20050607$lUSA01$h0906 996 $aGrundprobleme der analytischen Ontologie$952837 997 $aUNISA LEADER 00815nam0-22002891i-450 001 990004320080403321 005 20240212165436.0 010 $a3-518-11169-8 035 $a000432008 035 $aFED01000432008 035 $a(Aleph)000432008FED01 035 $a000432008 100 $a19990530d1983----km-y0itay50------ba 101 0 $aita 105 $ay-------001yy 200 1 $aBerichte von Hinze und Kunze$fVolker Braun 210 $aFrankfurt am Main$cSuhrkamp$d1983. 215 $a90 p.$d18 cm 225 1 $aSuhrkamp. Neue Folge$v169 700 1$aBraun,$bVolker$f<1939- >$0291319 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990004320080403321 952 $a831.92 BRAUN 06$bDip.f.m.3959$fFLFBC 959 $aFLFBC 996 $aBerichte von Hinze und Kunze$9487912 997 $aUNINA LEADER 06241nam 2201777z- 450 001 9910557793503321 005 20210501 035 $a(CKB)5400000000045453 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68695 035 $a(oapen)doab68695 035 $a(EXLCZ)995400000000045453 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMolecular Psychiatry 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (288 p.) 311 08$a3-03936-120-1 311 08$a3-03936-121-X 330 $aThe book highlights important aspects of Molecular Psychiatry, including molecular mechanisms, animal models, biomarkers, advanced methods, drugs and antidepressant response, as well as genetics and epigenetics. Molecular mechanisms are a vital part of the search for the biological basis of psychiatric disorders, providing molecular hints that can later be tested as biomarkers or targets for drug development. Animal models represent a commonly used approach to aid in this bench-to-bed translation; the examples here are social defeat stress and the Roman High-Avoidance (RHA) and the Roman Low-Avoidance (RLA) rats. For biomarkers, psychiatric disorders pose a particular challenge due to the tissue specificity of many currently investigated biomarkers; i.e., not all blood-based measures directly represent changes in the brain. The Ebook includes five articles focused on the challenges of identifying clinically and biologically relevant biomarkers for psychiatric disorders. Scientific progress typically is fostered by the development of new methods. The application of machine learning methods for the proper analysis of Big Data and induced pluripotent stem cells are examples outlined in this Ebook. Furthermore, three articles are devoted to the understanding of the mechanisms of actions of existing drugs with the ultimate goal of identifying ways to predict treatment response in patients. 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