LEADER 01538nam--2200421---450- 001 990000643420203316 005 20090610153355.0 010 $a88-243-1226-8 035 $a0064342 035 $aUSA010064342 035 $a(ALEPH)000064342USA01 035 $a0064342 100 $a20010927d1997----km-y0itay0103----ba 101 $aita 102 $aIT 105 $a||||||||001yy 200 1 $aAbilitazioni alle trasformazioni urbanistiche ed edilizie$elottizzazione concessione autorizzazione denuncia inizio attività riscontri di conformità$fRomilda Giuffré, Vincenzo Giuffré$ecommento comprensivo della "Bassanini-bis" 210 $aNapoli$cJovene$d1997 215 $aLVIII, 323 p.$d24 cm. 606 0 $aAree fabbricabili$xLegislazione 606 0 $aDiritto di edificare$xLegislazione 676 $a346.45045 700 1$aGIUFFRÉ,$bRomilda$0411509 701 1$aGIUFFRÉ,$bVincenzo$0352913 801 0$aIT$bsalbc$gISBD$gISBD 912 $a990000643420203316 951 $aXXIV.3.P 135 (IG V 587)$b14152 G$cIG V$d00232338 951 $aXXIV.3.P 135a (IG V 587)$b25564 G$cIG V$d00003618 951 $aXXIV.3.P 135b (IG V 587)$b44866 G.$cIG V$d00117186 959 $aBK 969 $aGIU 979 $aPATTY$b90$c20010927$lUSA01$h1418 979 $c20020403$lUSA01$h1714 979 $aPATRY$b90$c20040406$lUSA01$h1644 979 $aRENATO$b90$c20050627$lUSA01$h1152 979 $aRSIAV4$b90$c20090610$lUSA01$h1533 996 $aAbilitazioni alle trasformazioni urbanistiche ed edilizie$9626983 997 $aUNISA LEADER 02665nam 2200529z- 450 001 9910637793003321 005 20231214133632.0 010 $a3-0365-5224-3 035 $a(CKB)5470000001631606 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/94543 035 $a(EXLCZ)995470000001631606 100 $a20202212d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGenetics of Hearing Impairment 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (314 p.) 311 $a3-0365-5223-5 330 $aThe inner ear is a complex machinery at the cellular and molecular levels. Many different genes and proteins play roles in the development and maintenance of its structure and function, through participating in diverse molecular networks. A defect in any of these components can result in the loss of hearing. Consequently, hearing impairment encompasses a wide variety of disorders that are clinically and genetically heterogeneous. Understanding their genetic causes and their pathophysiological mechanisms, and characterizing the resulting phenotypes, are essential for developing novel therapies that target the specific defects. The articles and reviews in this book are representative of the many research lines that are currently active in the field, including recent advances in the genes and mutations involved in hearing impairment, the mechanisms through which mutations result in different syndromic or non-syndromic disorders, and the description of the associated phenotypes in humans and in animal models. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 606 $aGenetics (non-medical)$2bicssc 610 $ainner ear 610 $ahearing impairment 610 $agene identification 610 $adisease-causing mutations 610 $agenetic epidemiology 610 $agenotype&ndash 610 $aphenotype correlations 610 $apathophysiological mechanisms 610 $aomics 610 $agenome editing 610 $agene therapy 615 7$aResearch & information: general 615 7$aBiology, life sciences 615 7$aGenetics (non-medical) 700 $adel Castillo$b Ignacio$4edt$01331652 702 $aKremer$b Hannie$4edt 702 $adel Castillo$b Ignacio$4oth 702 $aKremer$b Hannie$4oth 906 $aBOOK 912 $a9910637793003321 996 $aGenetics of Hearing Impairment$93040534 997 $aUNINA