LEADER 01020nam0-22003131i-450- 001 990000954410403321 010 $a981-02-2359-5 035 $a000095441 035 $aFED01000095441 035 $a(Aleph)000095441FED01 035 $a000095441 100 $a20000920d19911996km-y0itay50------ba 101 0 $aeng 102 $aSG 105 $aa---a---101yy 200 1 $aNew Perspectives in Nuclear Structure$e5th International Spring Seminar on Nuclear Physics Ravello, Italy, May 22-26, 1995$feditor Aldo Covello 210 $aSingapore [etc.]$cWorld Scientific$dc1996 215 $axxiii, 662 p.$cill.$d23 cm 610 0 $aFisica nucleare 610 0 $aRadioattivitą 702 1$aCovello,$bAldo 710 11$aInternational Spring Seminar on Nuclear Physics,$d5.$f<1995 ;$eRavello>$044407 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990000954410403321 952 $a34AI-372.001$b20242$fFI1 959 $aFI1 996 $aNew Perspectives in Nuclear Structure$9357985 997 $aUNINA LEADER 01618cam0-2200517---450- 001 990000056420203316 005 20051021112124.0 010 $a0-674-99407-8 035 $a0005642 035 $aUSA010005642 035 $a(ALEPH)000005642USA01 035 $a0005642 100 $a20000914d19461999|||y0itay0103----ba 101 0 $aeng$alat 102 $aus 105 $a||||||||001|y 200 1 $aHistory of Alexander$ebook 6-10$fQuintus Curtius$gwith an English translation by John C. 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From Genetics to Epigenetics: The Steps of a Path -- 2. Molecular basis of epigenetic mechanisms -- 3. Epigenetics and Endocrine Disruptors -- 4. New insights into the fetal programming hypothesis of the linkage between neurodevelopmental disorders and impaired neurogenesis -- 5. The Placenta and the development of human health -- 6. Epigenetics and cancer -- 7. Epigenetics in Autoimmune Diseases -- 8. Epigenetics and Systemic Vasculitis -- 9. Epigenetics and Allergic Diseases -- 10. The Role of Epigenetics in Autoinflammatory Diseases -- 11. Epigenetics and immune-mediated diseases -- 12. Epigenetics and Inherited Metabolic Disorders -- 13. Epigenetics and Psychiatric Diseases -- 14. The metabolomics revolution toward personalized medicine: the case of gestational diabetes -- 15. Epigenetics and Microbiome -- Index. 330 $aEpigenetics, as well as all -omics fields of study, such as transcriptomics, proteomics and metabolomics, have caused a revolution in all branches of medicine in recent years. This book provides a detailed evidence-based overview of the latest developments in how the recent acquisitions on the human genome and epigenome is relevant, and how it impacts our understanding of rare diseases of the immune system. The first part features the evolving thread from genetics to epigenetics, their molecular basis, endocrine disruptors, as well as chapters devoted to the fetal programming hypothesis and functional basis of neurodevelopment, and the placenta as originating element. Successive chapters include contributions on the impact of epigenetics on cancer, as well as a comprehensive array of disorders as autoimmune disorders, allergic and metabolic diseases, systemic vasculitis, aging and inflammatory diseases, neurological and psychiatric conditions. The overview closes with considerations on the ?-Omics? revolution and precision medicine, and the reflection of epigenetics on the microbiome. By providing guidance on how the latest information can be applied by the medical practitioner in day-to-day clinical practice, and collating the latest developments in rare diseases treatments to the ?omics? that are relevant for the clinician while advocating for a patient-centered approach, Epigenetics and Rare Diseases will be a valued resource for clinicians, healthcare professionals, and patient associations. 410 0$aRare Diseases of the Immune System,$x2283-6403 606 $aImmunology 606 $aRheumatology 606 $aGenetics 606 $aOncology 606 $aImmunology 606 $aRheumatology 606 $aGenetics and Genomics 606 $aOncology 615 0$aImmunology. 615 0$aRheumatology. 615 0$aGenetics. 615 0$aOncology. 615 14$aImmunology. 615 24$aRheumatology. 615 24$aGenetics and Genomics. 615 24$aOncology. 676 $a571.96 676 $a616.079 700 $aEmmi$b Lorenzo$0101334 701 $aFanos$b Vassilios$01852970 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911034954403321 996 $aEpigenetics and Rare Diseases$94448974 997 $aUNINA