LEADER 01334nam 22004093u 450 001 9910457682903321 005 20210107002118.0 010 $a1-84964-698-8 035 $a(CKB)2550000000073573 035 $a(EBL)3386570 035 $a(MiAaPQ)EBC3386570 035 $a(EXLCZ)992550000000073573 100 $a20151005d2011|||| u|| | 101 0 $aeng 135 $aur|n|---||||| 200 10$aTowards a Second Republic$b[electronic resource] $eIrish Politics and the Celtic Tiger 210 $aLondon $cPluto Press$d2011 215 $a1 online resource (288 p.) 300 $aDescription based upon print version of record. 311 $a0-7453-3056-8 606 $aEconomics -- Ireland -- 21st century 606 $aIreland -- Economic conditions -- 21st century 606 $aIreland -- Economic policy -- 21st century 608 $aElectronic books. 615 4$aEconomics -- Ireland -- 21st century. 615 4$aIreland -- Economic conditions -- 21st century. 615 4$aIreland -- Economic policy -- 21st century. 676 $a330.9417 700 $aKirby$b Peadar$0853770 701 $aMurphy$b Mary P$0112254 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910457682903321 996 $aTowards a Second Republic$92014056 997 $aUNINA LEADER 00979nam2 22002651i 450 001 UON00423691 005 20231205104837.522 100 $a20130502f1937 |0itac50 ba 101 $afre 102 $aFR 105 $a|||| 1|||| 200 1 $aˆ13.:‰Mission a Rome$fJules Romains 210 $aParis$cFlammarion$dc1937 215 $a312 p.$d18 cm. 461 1$1001UON00423666$12001 $aˆLes ‰hommes de bonne volontè$fJules Romains$v13 620 $aFR$dParis$3UONL002984 676 $a840.9$cLetteratura francese. 1900-$v21 700 1$aROMAINS$bJules$3UONV159197$0188802 712 $aFlammarion$3UONV246340$4650 801 $aIT$bSOL$c20240220$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00423691 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI Francese VI A ROM 13 $eSI MR 11062/11 5 13 $sBuono 996 $aMission a Rome$91185024 997 $aUNIOR LEADER 04075nam 22006854a 450 001 9910963123103321 005 20251116215721.0 010 $a9786611730451 010 $a9781281730459 010 $a1281730459 010 $a9780300129663 010 $a0300129661 024 7 $a10.12987/9780300129663 035 $a(CKB)1000000000471991 035 $a(StDuBDS)BDZ0022171458 035 $a(SSID)ssj0000201499 035 $a(PQKBManifestationID)11184383 035 $a(PQKBTitleCode)TC0000201499 035 $a(PQKBWorkID)10245497 035 $a(PQKB)11781868 035 $a(StDuBDS)EDZ0000158001 035 $a(MiAaPQ)EBC3420064 035 $a(DE-B1597)485546 035 $a(OCoLC)1024032087 035 $a(DE-B1597)9780300129663 035 $a(Au-PeEL)EBL3420064 035 $a(CaPaEBR)ebr10170754 035 $a(OCoLC)923589373 035 $a(Perlego)1089666 035 $z(OCoLC)1024032087 035 $a(EXLCZ)991000000000471991 100 $a20010123d2001 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMeselson, Stahl, and the replication of DNA $ea history of "the most beautiful experiment in biology" /$fFrederic Lawrence Holmes 205 $a1st ed. 210 $aNew Haven, CT $cYale University Press$d2001 215 $a1 online resource (1 online resource (xii, 503 p.) ) $cill 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a9780300085402 311 08$a0300085400 320 $aIncludes bibliographical references (p. [449]-496) and index. 327 $aMachine generated contents note: Chapter One The Replication Problem 11 -- Chapter Two Meselson and Stahl 49 -- Chapter Three Twists and Turs 75 -- Chapter Four Crossing Fields: Chemical Bonds to Biological Mutants 116 -- Chapter Five Dense Solutions 157 -- Chapter Six The Big Machine 183 -- Chapter Seven Working at High Speed 215 -- Chapter Eight The Unseen Band 272 -- Chapter Nine One Discovery, Three Stories 303 -- Chapter Ten An Extremely Beautiful Experiment 319 -- Chapter Eleven Centrifugal Forces 352 -- Chapter Twelve The Subunits of Semiconservative Replication 388 -- Chapter Thirteen Images of an Experiment 412 -- Chapter Fourteen Afterword 435. 330 $aIn 1957 two young scientists, Matthew Meselson and Frank Stahl, produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a "most beautiful" experiment whose beauty was tied to its simplicity. Yet the investigative path that led to the experiment was anything but simple, Frederic L. Holmes shows in this masterful account of Meselson and Stahl's quest.This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research--its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty. Holmes uses research logs, experimental films, correspondence, and interviews with the participants to record the history of Meselson and Stahl's research, from their first thinking about the problem through the publication of their dramatic results. Holmes also reviews the scientific community's reception of the experiment, the experiment's influence on later investigations, and the reasons for its reputation as an exceptionally beautiful experiment. 606 $aDNA replication$xExperiments$xHistory 606 $aMolecular biology$xExperiments$xHistory 615 0$aDNA replication$xExperiments$xHistory. 615 0$aMolecular biology$xExperiments$xHistory. 676 $a572.8/6 700 $aHolmes$b Frederic Lawrence$0726772 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910963123103321 996 $aMeselson, Stahl, and the replication of DNA$94364680 997 $aUNINA