LEADER 01151nam0 22003011i 450 001 UON00077371 005 20231205102416.454 010 $a90-619-1096-X 100 $a20020107d1982 |0itac50 ba 101 $aeng 102 $aNL 105 $a|||| ||||| 200 1 $aˆA ‰land between two Niles$eQuaternary geology and biology of the Central Sudan$fEdited by Martin A.J. Williams, D.A. Adamson 210 $aRotterdam$cBalkema$d1982 215 $ax, 246 p.$d24 cm 606 $aPALEOBOTANICA$xSudan$3UONC023558$2FI 606 $aPALEOGEOGRAFIA$xSudan$3UONC023559$2FI 620 $aNL$dRotterdam$3UONL001474 676 $a561.1$cPALEOBOTANICA$v21 702 1$aADAMSON$bDonald A.$3UONV050755 702 1$aWILLIAMS$bMartin A.J.$3UONV044763 712 $aBalkema$3UONV257131$4650 801 $aIT$bSOL$c20240220$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00077371 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI AFR ARCH 094 $eSI AA 18160 5 094 996 $aLand between two Niles$91299686 997 $aUNIOR LEADER 03060nam 2200385z- 450 001 9910136403103321 005 20210211 035 $a(CKB)3710000000612063 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53809 035 $a(oapen)doab53809 035 $a(EXLCZ)993710000000612063 100 $a20202102d2014 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aModulators of hypothalamic-pituitary-gonadal axis for the control of spermatogenesis and sperm quality in vertebrates 210 $cFrontiers Media SA$d2014 215 $a1 online resource (159 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-358-6 330 $aSpermatogenesis is a process highly conserved throughout vertebrate species and is mainly under hypothalamic-pituitary control. It occurs in the testis in a stepwise fashion so that committed spermatogonia develop into spermatocytes and enter meiosis to produce round spermatids. These undergo a morphological transformation (spermiogenesis) into mature spermatids (i.e.: spermatozoa), which are differentially released from Sertoli cells (spermiation) depending on the species. In mammals, further transformations are necessary to form mature spermatozoa, suitable for fertilization. Gonadotropins, mainly responsive to gonadotropin-releasing hormone, control spermatogenesis through specific receptors located at the gonadal level. However, besides the endocrine route, the chemical mediators may also act locally in the gonad. Indeed, it is documented that testis physiology, including steroidogenesis and spermatogenesis, does not fully account for traditional endocrine control but an intragonadal network of autocrine and/or paracrine regulators also exists, whose activity, via cell-to-cell communication, regulates germ cell progression and development of qualitatively mature spermatozoa. Of note, a number of testicular modulators, such as gonadotropin releasing hormone, Kiss-peptin, endocannabinoids, has been early isolated in the brain and latest in the gonads. To fully understand precise mechanisms underlying the functional interaction of this intricate network, needless to say, it is crucially required to have detailed information about modulators and target cells. Through synergy between the respective specializations of all the authors, this topic reviewed emerging knowledge about neuroendocrine and local mediators controlling germ cell progression and maturation. 610 $ahypothalamic 610 $asperm quality 610 $aSpermatogenesis 610 $aVertebrates 700 $aRosaria Meccariello$4auth$01309749 702 $aRiccardo Pierantoni$4auth 702 $aSilvia Fasano$4auth 702 $aGilda Cobellis$4auth 906 $aBOOK 912 $a9910136403103321 996 $aModulators of hypothalamic-pituitary-gonadal axis for the control of spermatogenesis and sperm quality in vertebrates$93029557 997 $aUNINA