LEADER 01215cam0-22003251i-450- 001 990007419920403321 005 20161029193333.0 035 $a000741992 035 $aFED01000741992 035 $a(Aleph)000741992FED01 035 $a000741992 100 $a20030423d1676----km-y0itay50------ba 101 0 $aita 140 $aa-------------------bb0----- 200 1 $aDe' pensieri diuersi di Alessandro Tassoni. Libri dieci. Corretti, ampliati, e arricchiti in questa vltima impressione per tutto dall'auttore di nuoue curiositą. ... Con la tauola de' libri, quesiti, e capitoli, la qual č diligentemente reuista 210 $aIn Venetia$cper Domenico Miloco$d1676 215 $a[8], 361 [i.e. 363], [5] p.$dfol. 306 $aMarca (O30) sul frontespizio 307 $aErrore di numerazione: p. 306-363 paginate erroneamente 304-361 307 $aCapilettera xilografici istoriati 307 $aSegn.: a? A-Z? 620 $aItalia.$dVenezia 700 1$aTassoni,$bAlessandro$f<1565-1635>$0152520 719 00$aMiloco,$gDomenico$4650 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aAQ 912 $a990007419920403321 952 $aBIB. BAT. RARI 94$b18008$fBAT 959 $aBAT 997 $aUNINA LEADER 01107nam0 22002891i 450 001 UON00032432 005 20231205102107.324 010 $a97-946107-6-3 100 $a20020107d1991 |0itac50 ba 101 $aeng 102 $aID 105 $a|||| 1|||| 200 1 $aBali in the 19th century$fIde Anak Agung Gde Agung 210 $aJakarta$cYayasan Obor Indonesia$d1991 215 $axxi, 292 p.$cill.$d20 cm 606 $aINDONESIA$xSTORIA$xSEC. XIX$3UONC008336$2FI 606 $aBALI (INDONESIA)$xVita sociale e costumi$3UONC090594$2FI 620 $aID$dJakarta$3UONL000164 686 $aINDS IV$cINDONESIA - STORIA$2A 700 1$aAGUNG$bIde Anak Agung Gde$3UONV021520$0645497 712 $aYayasan Obor Indonesia$3UONV248215$4650 801 $aIT$bSOL$c20240220$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00032432 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI INDS IV 101 N $eSI SA 86798 5 101 N 996 $aBali in the 19th century$91191985 997 $aUNIOR LEADER 04734nam 22007335 450 001 9910298348803321 005 20200706205034.0 010 $a1-4939-0434-5 024 7 $a10.1007/978-1-4939-0434-1 035 $a(CKB)3710000000087962 035 $a(EBL)1698086 035 $a(OCoLC)871042065 035 $a(SSID)ssj0001177304 035 $a(PQKBManifestationID)11794511 035 $a(PQKBTitleCode)TC0001177304 035 $a(PQKBWorkID)11154944 035 $a(PQKB)10328882 035 $a(MiAaPQ)EBC1698086 035 $a(DE-He213)978-1-4939-0434-1 035 $a(PPN)176751122 035 $a(EXLCZ)993710000000087962 100 $a20140207d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aGene Therapy for HIV $eFrom Inception to a Possible Cure /$fby Gerhard Bauer, Joseph S. Anderson 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014. 215 $a1 online resource (77 p.) 225 1 $aSpringerBriefs in Biochemistry and Molecular Biology,$x2211-9353 300 $aDescription based upon print version of record. 311 $a1-4939-0433-7 320 $aIncludes bibliographical references. 327 $aPrinciples of Gene Therapy -- Injection of Naked DNA -- Non-Viral Gene Transfer (Transfection) Methods -- Viral gene transfer (transduction) methods -- Retroviruses -- Other viruses.- History of Gene Therapy.- Principles of HIV Gene Therapy.- Gene Therapy Vectors.- Lentiviral vectors.- Other modifications and additions.- Anti-HIV genes.- RNA-strategies.- Vector production.- Stem Cells for HIV Gene Therapy.- Pluripotent stem cells.- Animal Models Used in HIV Gene Therapy -- Murine models.- HIV infections in humanized mice.- Non-human primates.- Manufacturing of a GMP grade product for HIV gene therapy.- Clinical applications of HIV gene therapy.-  Clinical trials of T cell gene therapy.- Stem cell gene therapy clinical trials for HIV.- Is A Cure for HIV Possible?. 330 $aThis Brief describes the concept and realization of gene therapy for HIV from the unique historic perspective and insight of two pioneers of the clinical applications of stem cell gene therapy for HIV. Gerhard Bauer applied ribozyme-anti-HIV and other vectors to manufacture clinical grade, HIV-resistant hematopoietic stem cells for the first patients that received stem cell gene therapy for HIV, including the first child in the world and the first fully marrow-ablated HIV infected patient. Joseph Anderson developed the most recent and most potent combination anti-HIV lentiviral vectors and pluripotent stem cell applications for HIV gene therapy and tested these in the appropriate in vitro and vivo models, paving the way for novel HIV gene therapy approaches to possibly cure patients. In Gene Therapy for HIV, Bauer and Anderson discuss the unique aspects of this therapy, including its limitations and proper safety precautions and outline a path for a possible functional cure for HIV using stem cell gene therapy based on a cure already achieved with a bone marrow stem cell transplantation performed in Germany using donor stem cells with a naturally arising CCR5 mutation. In addition, the Brief provides a thorough and methodical explanation of the basics of gene therapy, gene therapy vector development, in vitro and in vivo models for HIV gene therapy and clinical applications of HIV gene therapy, including Good Manufacturing Practices. 410 0$aSpringerBriefs in Biochemistry and Molecular Biology,$x2211-9353 606 $aGene therapy 606 $aVirology 606 $aImmunology 606 $aVaccines 606 $aGene Therapy$3https://scigraph.springernature.com/ontologies/product-market-codes/B12020 606 $aVirology$3https://scigraph.springernature.com/ontologies/product-market-codes/B22003 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aVaccine$3https://scigraph.springernature.com/ontologies/product-market-codes/B16010 615 0$aGene therapy. 615 0$aVirology. 615 0$aImmunology. 615 0$aVaccines. 615 14$aGene Therapy. 615 24$aVirology. 615 24$aImmunology. 615 24$aVaccine. 676 $a616.042 700 $aBauer$b Gerhard$4aut$4http://id.loc.gov/vocabulary/relators/aut$0159666 702 $aAnderson$b Joseph S$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298348803321 996 $aGene Therapy for HIV$92513136 997 $aUNINA