LEADER 01168nam0 22002891i 450 001 UON00011231 005 20231205101934.573 100 $a20020107d1991 |0itac50 ba 101 $aita 102 $aIT 105 $a|||| 1|||| 200 1 $aChiesa Arcipretale del Salvatore a Pontelandolfo$fa cura di Gabriele Capone e Gemma T. Colesanti 210 $aMorcone$cComunità Montana Alto Tammaro$d1991 215 $a61 p.$cill.$d24 cm 410 1$1001UON00011213$12001 $aˆGli ‰Archivi locali$fComunità Montana Alto Tammaro$v1 620 $dMorcone$3UONL000554 686 $aGEO XI$cGEO-GEOGRAFIA STORICA$2A 702 1$aCAPONE$bGabriele$3UONV008712 702 1$aCOLESANTI$bGemma T.$3UONV008713 712 $aComunità Montana Alto Tammaro$3UONV247279$4650 801 $aIT$bSOL$c20240220$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00011231 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI geo DIP.SC.SOC. 187 $eSI SA 76143 5 187 996 $aChiesa Arcipretale del Salvatore a Pontelandolfo$91178763 997 $aUNIOR 998 $a1 LEADER 03544nam 22005775 450 001 9910298429303321 005 20251116204434.0 010 $a981-13-0484-X 024 7 $a10.1007/978-981-13-0484-2 035 $a(PPN)229501257 035 $a(CKB)4100000005323298 035 $a(DE-He213)978-981-13-0484-2 035 $a(MiAaPQ)EBC5471996 035 $a(EXLCZ)994100000005323298 100 $a20180720d2018 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHIV Vaccines and Cure $eThe Path Towards Finding an Effective Cure and Vaccine /$fedited by Linqi Zhang, Sharon R. Lewin 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2018. 215 $a1 online resource (XV, 318 p. 21 illus., 16 illus. in color.) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1075 311 08$a981-13-0483-1 327 $aHIV Vaccine Efficacy Trials: RV144 and beyond -- HIV T-cell vaccines -- HIV broadly neutralizing antibodies: VRC01 and beyond -- Structural features of broadly neutralizing antibodies and rational design of vaccine -- Monkey models and HIV vaccine research -- Treatment of HIV for the Prevention of Transmission in Discordant Couples and at the Population Level -- HIV persistence on antiretroviral therapy and barriers to a cure -- The molecular biology of HIV latency -- Cellular determinants of HIV persistence on antiretroviral therapy -- In Vitro and In Vivo Models of HIV Latency -- Measuring HIV persistence on antiretroviral therapy -- Clinical interventions in HIV cure research. 330 $aThis book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v1075 606 $aMedical virology 606 $aVaccines 606 $aImmunology 606 $aLaboratory animals 606 $aVirology$3http://scigraph.springernature.com/things/product-market-codes/B22003 606 $aVaccine$3http://scigraph.springernature.com/things/product-market-codes/B16010 606 $aImmunology$3http://scigraph.springernature.com/things/product-market-codes/B14000 606 $aAnimal Models$3http://scigraph.springernature.com/things/product-market-codes/L25050 615 0$aMedical virology. 615 0$aVaccines. 615 0$aImmunology. 615 0$aLaboratory animals. 615 14$aVirology. 615 24$aVaccine. 615 24$aImmunology. 615 24$aAnimal Models. 676 $a616.9101 702 $aZhang$b Linqi$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aLewin$b Sharon$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298429303321 996 $aHIV Vaccines and Cure$92505679 997 $aUNINA