LEADER 02338nam 2200481z- 450 001 9911115489403321 005 20210212 035 $a(CKB)3800000000216197 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/61873 035 $a(oapen)doab61873 035 $a(EXLCZ)993800000000216197 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aVascular Inflammation in Systemic Autoimmunity 210 $cFrontiers Media SA$d2017 215 $a1 online resource (148 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-090-2 330 $aPlasticity and dynamism characterize the immune system as a tissue-integrating network with defensive functions. Blood and lymphatic vessel trees constitute the most evident and intuitive physical platform for the development of the net of interactions between immune cells, body tissues and foreign agents. Moreover vessel repair and immune patrolling are intimately linked physiological functions with common evolutionary roots. Not surprisingly variable degrees of vascular inflammation are often detectable in the setting of systemic inflammation and autoimmunity, whereas research in the field of cardiovascular pathology is progressively converging towards the identification of a common inflammatory background. The definition of the role of vascular inflammation in causing, sustaining and/or predicting the development of systemic autoimmunity constitute a challenging, unexplored frontier towards the development of a new generation of treatments and a better patient care. 606 $aMedicine$2bicssc 610 $aAutoimmunity 610 $aEndothelium 610 $aGenetics 610 $aNeutrophils 610 $aPathogenesis 610 $aplatelets 610 $aremodeling 610 $aT-Lymphocytes 610 $avascular inflammation 610 $aVasculitis 615 7$aMedicine 700 $aCornelia Weyand$4auth$02003878 702 $aAugusto Vaglio$4auth 702 $aAngelo A. Manfredi$4auth 702 $aGiuseppe A. Ramirez$4auth 906 $aBOOK 912 $a9911115489403321 996 $aVascular Inflammation in Systemic Autoimmunity$94789554 997 $aUNINA