LEADER 04203nam 2200601Ia 450 001 9911105131403321 005 20251017110054.0 010 $a0-309-16645-4 010 $a1-280-17663-6 010 $a9786610176632 010 $a0-309-52844-5 035 $a(CKB)111087027010032 035 $a(OCoLC)60365231 035 $a(CaPaEBR)ebrary10051686 035 $a(SSID)ssj0000114742 035 $a(PQKBManifestationID)11131704 035 $a(PQKBTitleCode)TC0000114742 035 $a(PQKBWorkID)10125398 035 $a(PQKB)10515791 035 $a(Au-PeEL)EBL3564033 035 $a(CaPaEBR)ebr10051686 035 $a(OCoLC)54863693 035 $a(MiAaPQ)EBC3564033 035 $a(DNLM)1640984 035 $a(BIP)53858615 035 $a(BIP)10324225 035 $a(EXLCZ)99111087027010032 100 $a20040415d2004 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBridging the bed-bench gap $econtributions of the Markey Trust /$fCommittee on the Evaluation of the Lucille P. Markey Charitable Trust Programs in Biomedical Sciences ; Board on Higher Education and Workforce, Policy and Global Affairs Division, National Research Council of the National Academies 205 $a1st ed. 210 $aWashington, D.C. $cNational Academies Press$dc2004 215 $a1 online resource (133 p.) 300 $a"This study was supported by Contract/Grant No. OSEP-97-M-03-A between the National Academy of Sciences and the Lucille P. Markey Charitable Trust."--T.p. verso. 311 08$a0-309-09112-8 320 $aIncludes bibliographical references. 327 $aFrontMatter -- Preface -- Contents -- Executive Summary -- Introduction -- History of the Markey Trust -- Grant Programs -- Assessing the Markey General Organizational Grants Program -- The Biomedical Research Environment in the 1980s -- Closing the Bed-Bench Gap -- The Current Biomedical Research Environment -- Conclusions and Observations for Philanthropic Funders -- References -- Appendixes -- A Bridge Building Between Medicine and Basic Science -- B The Endangered Physician-Scientist: Opportunities for Revitalization Emerge -- C Workshop on Training Programs in Patient-Oriented Pathobiology for Basic Scientists -- D Workshop on Training Programs in Patient-Oriented Pathobiology for Basic Scientists -- E Descriptions of Programs Participating in the Workshop on Training Programs in Patient-Oriented Pathobiology for Basic Scientists -- F Summary of Site Visits to Markey-Funded Programs That Provided Training in Basic Research to Physicians -- G Biographies of Members of the Lucille P. Markey Charitable Trust Programs in Biomedical Sciences Committee. 330 $aSince the 1970s there has been a serious gap between fundamental biological research and its clinical application. In response to this gap the Lucille P. Markey Charitable Trust instituted the General Organizational Grants program, which funded two types of awards to provide training that would bridge the bed-bench gap. These training awards fell into two categories: (1) those that provided significant opportunities for M.D.s to engage in basic research during and immediately following medical school and residency, and (2) those that provided significant clinical exposure for Ph.D.s while they were predoctoral or postdoctoral students. These grants were intended to close the widening gap between rapid advances in our understanding of the biological process and the translation of that knowledge into techniques for preventing diseases. This report examines the General Organizational Grant programs, identifies best practices, and provides observations for future philanthropic funders. 606 $aMedicine$xResearch grants 615 0$aMedicine$xResearch grants. 676 $a610/.7/2 712 02$aNational Research Council (U.S.).$bCommittee on the Evaluation of the Lucille P. Markey Charitable Trust Programs in Biomedical Sciences. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911105131403321 996 $aBridging the bed-bench gap$94769376 997 $aUNINA