LEADER 02885nam  2200637Ia 450 
001 9911094303703321
005 20251117074714.0
010   $a9786612763595
010   $a9781282763593
010   $a1282763598
010   $a9789814299176
010   $a9814299170
035   $a(CKB)2490000000001876
035   $a(EBL)731112
035   $a(OCoLC)670430601
035   $a(SSID)ssj0000416069
035   $a(PQKBManifestationID)11299043
035   $a(PQKBTitleCode)TC0000416069
035   $a(PQKBWorkID)10419391
035   $a(PQKB)10743255
035   $a(MiAaPQ)EBC731112
035   $a(WSP)00007667
035   $a(Au-PeEL)EBL731112
035   $a(CaPaEBR)ebr10422541
035   $a(CaONFJC)MIL276359
035   $a(Perlego)848596
035   $a(EXLCZ)992490000000001876
100   $a20100331d2010      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aDNA polymerases $ediscovery, characterization and functions in cellular DNA transactions /$fUlrich Hubscher ... [et al.]
205   $a1st ed.
210   $aSingapore $cWorld Scientific$dc2010
215   $a1 online resource (340 p.)
300   $aDescription based upon print version of record.
311 08$a9789814299169 
311 08$a9814299162 
320   $aIncludes bibliographical references.
327   $aPreface; Contents; 1. History and Discovery of DNA Polymerases; 2. DNA Polymerases in the Three Kingdoms of Life: Bacteria, Archaea and Eukaryotes; 3. Structural and Functional Aspects of the Prokaryotic and Archaea DNA Polymerase Families; 4. Structural and Functional Aspects of the Eukaryotic DNA Polymerase Families; 5. Global Functions of DNA Polymerases; 6. Viral DNA Polymerases; 7. Synthetic Evolution of DNA Polymerases with Novel Properties; 8. DNA Polymerases and Diseases; 9. DNA Polymerases and Chemotherapy
330   $aMaintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex physiological processes of DNA replication and repair. Besides the tasks in vivo, DNA polymerases are the workhorses in numerous biotechniques such as polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids-based diagnostics, as well as techniques to analyze ancient and otherwise damaged DNA. The authors have recently witnessed the discovery of a plethora of novel DNA polymerases with specialized properties whose physiological func
606   $aDNA polymerases
606   $aBiochemistry
615  0$aDNA polymerases.
615  0$aBiochemistry.
676   $a572.86
701   $aHu?bscher$b Ulrich$01998092
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9911094303703321
996   $aDNA polymerases$94779443
997   $aUNINA