LEADER 04392nam 22007095 450 001 9911065997603321 005 20260221120401.0 010 $a9783032124357$b(electronic bk.) 010 $z9783032124340 024 7 $a10.1007/978-3-032-12435-7 035 $a(MiAaPQ)EBC32556483 035 $a(Au-PeEL)EBL32556483 035 $a(CKB)45408935200041 035 $a(DE-He213)978-3-032-12435-7 035 $a(EXLCZ)9945408935200041 100 $a20260221d2026 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAshbya gossypii in Biotechnology /$fby Tatiana Q Aguiar, Eduardo Coelho, Lucília Domingues 205 $a1st ed. 2026. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2026. 215 $a1 online resource (115 pages) 225 1 $aSpringerBriefs in Molecular Science,$x2191-5415 311 08$aPrint version: Aguiar, Tatiana Q. Ashbya Gossypii in Biotechnology Cham : Springer,c2026 9783032124340 327 $aA gossypii history -- A gossypii physiology and metabolism -- Optimization of the A gossypii natural metabolism for biotechnological applications -- Metabolic engineering and synthetic biology strategies -- Bioprocess and biosustainable strategies -- Perspectives. 330 $aThis book provides a comprehensive overview of the filamentous fungus Ashbya gossypii, an emerging microbial host in industrial biotechnology. Recognized for its natural ability to overproduce riboflavin (vitamin B2), A. gossypii has evolved from a niche model organism into a promising candidate for sustainable biotechnological applications. This book synthesizes decades of foundational research and recent advances to present a complete picture of the organism?s utility in modern biosciences. The book begins with a detailed history of A. gossypii (Chapter 1), tracing its discovery, early industrial uses, and the scientific milestones that led to its current role in biotechnology. Chapter 2 covers its physiology and metabolism, highlighting the unique features of its multinucleated hyphae, aerobic metabolism, and natural biosynthetic capabilities. Chapter 3 focuses on how A. gossypii?s natural metabolism is being optimized for industrial applications. It covers cutting-edge metabolic engineering and synthetic biology strategies, showcasing how genetic tools have been used to redirect carbon flux, enhance product yields, and expand the range of biosynthesized compounds. Chapter 4 addresses bioprocessing innovations and biosustainable strategies, such as using renewable feedstocks, optimizing cultivation conditions, and improving strain robustness for industrial scalability. The final chapter (Chapter 5) offers forward-looking perspectives, identifying future opportunities and challenges in leveraging A. gossypii for green chemistry and biotechnological fields. As sustainability becomes a cornerstone of modern industry, this book positions A. gossypii as a key player in the next generation of microbial production platforms. Targeted at researchers, biotechnologists, and students in microbiology and metabolic engineering, this book is both a foundational reference and a roadmap for innovation in fungal biotechnology. 410 0$aSpringerBriefs in Molecular Science,$x2191-5415 606 $aBiotechnology 606 $aBiochemical engineering 606 $aBiochemistry 606 $aMetabolism 606 $aCytology 606 $aSynthetic biology 606 $aChemical Bioengineering 606 $aBiotechnology 606 $aBioprocess Engineering 606 $aMetabolic Pathways 606 $aSynthetic Biology 606 $aBiochemistry 615 0$aBiotechnology. 615 0$aBiochemical engineering. 615 0$aBiochemistry. 615 0$aMetabolism. 615 0$aCytology. 615 0$aSynthetic biology. 615 14$aChemical Bioengineering. 615 24$aBiotechnology. 615 24$aBioprocess Engineering. 615 24$aMetabolic Pathways. 615 24$aSynthetic Biology. 615 24$aBiochemistry. 676 $a660.63 700 $aAguiar$b Tatiana Q$01895466 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9911065997603321 996 $aAshbya gossypii in Biotechnology$94548349 997 $aUNINA