LEADER 04208nam 2200949z- 450 001 9911053120803321 005 20230911 035 $a(CKB)5690000000228508 035 $a(oapen)doab113866 035 $a(EXLCZ)995690000000228508 100 $a20230920c2023uuuu -u- - 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aBreeding, Genetics and Safety Production of Dairy Cattle 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2023 215 $a1 online resource (168 p.) 311 08$a3-0365-8247-9 330 $aThe integration of various omics information-such as DNA, RNA, protein, and epigenetic regulation-brings new opportunities for the mining of important economic traits of animals and the analysis of molecular genetic mechanisms. Over the last three decades, world milk production has increased by more than 59%, from 530 million tonnes to 843 million tonnes. However, the genetic mechanisms behind milk fat traits remain largely undetermined. Milk is rich in fatty acids, proteins, and eight essential amino acids needed by the human body. The fatty acids in milk, namely, dodecylic acid, myristic acid, stearic acid, and palmitic acid, are the main energy substances in the human body, accounting for approximately 5, 10, 8, and 27 % of total fatty acids, respectively. Thus, decoding the genetics of milk fat traits can have a potential impact on product development, international trade, and consumption of milk components. This Special Issue focuses on applying the aforementioned advances to explore gene regulation and its molecular mechanisms in milk fat traits. The topics include but are not limited to: Research and application surrounding the genetic basis of important milk fat traits; Mining and function of excellent genetic resources for milk fat traits; Genetics of nutrition metabolism regulation and efficient production of milk fat; Epigenetic research on genes implicated in milk fat traits; High-throughput sequencing research surrounding genetics of milk fat traits; Construction of gene (including circRNA, lincRNA, miRNA, and mRNA) expression regulatory network maps. 606 $aBiology, life sciences$2bicssc 606 $aResearch & information: general$2bicssc 606 $aTechnology, engineering, agriculture$2bicssc 610 $aalleles 610 $aapoptosis 610 $aAPPs 610 $abeta-oxidation 610 $abovine mammary epithelial cells 610 $abovine mastitis 610 $abreeds 610 $acofilin-1 610 $acofilin-2 610 $acow 610 $acow mammary cells 610 $adairy cattle 610 $aDDIT3 610 $adetection tools 610 $aDNA methylation 610 $adrug resistance 610 $aE. coli 610 $aEscherichia coli 610 $aexpression pattern 610 $afertility 610 $agene expression 610 $agenetic effect 610 $agenetic-load classification 610 $aGPAM 610 $ahaplotype 610 $aheard health status 610 $ahereditary diseases 610 $aHolstein cattle 610 $alipid metabolism 610 $aLycium barbarum polysaccharide 610 $am6A methylation 610 $aMAC-T 610 $amammary epithelial cells 610 $aMAPK signaling 610 $amilk fat 610 $amilk production 610 $amilk production traits 610 $amilk-fat synthesis 610 $amiR-125a 610 $amiR-29 610 $amolecular mechanism 610 $amutations 610 $amyoblast differentiation 610 $an/a 610 $aovarian follicle 610 $aperoxisome 610 $aSAA 610 $aSAA1 610 $aSOCS3 610 $avery long-chain fatty acids 610 $a?-lactams 615 7$aBiology, life sciences 615 7$aResearch & information: general 615 7$aTechnology, engineering, agriculture 906 $aBOOK 912 $a9911053120803321 996 $aBreeding, Genetics and Safety Production of Dairy Cattle$94527493 997 $aUNINA