LEADER 03546nam 22006735 450 001 9911031639303321 005 20251008131252.0 010 $a3-032-00761-5 024 7 $a10.1007/978-3-032-00761-2 035 $a(CKB)41571848100041 035 $a(MiAaPQ)EBC32333420 035 $a(Au-PeEL)EBL32333420 035 $a(OCoLC)1545124179 035 $a(DE-He213)978-3-032-00761-2 035 $a(EXLCZ)9941571848100041 100 $a20251008d2025 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCancer and Surrounding Environment $eEtiologies and Tumor Microenvironment /$fedited by Nima Rezaei 205 $a1st ed. 2025. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2025. 215 $a1 online resource (1195 pages) 225 1 $aHandbook of Cancer and Immunology,$x3091-3675 ;$v3 311 08$a3-032-00760-7 327 $aIntroduction to Tumor Microenvironment -- Tertiary Lymphoid Structure Formation and Function in the Tumor Microenvironment -- Role of Immune Cells in the Tumor Microenvironment -- Advances in Tumor Microenvironment Immune Profiling -- Angiogenesis and the Tumor Microenvironment -- Tumor Microenvironment Complexity A Pathological Milieu that Innately Modulates Cancer Progression -- Macrophage Polarization in the Tumor Microenvironment Modulation and Mimicry -- Neuroimmune Crosstalk in the Tumor Microenvironment -- Role of C Type Lectins in the Tumor Microenvironment -- Spatial Technologies A Game Changer for Studying the Tumor Microenvironment. 330 $aThe rapid flow of studies in the field of cancer and immunology during the last decades has increased our understanding of the interactions between the immune system and cancerous cells. In particular, it has been well-known that such interactions result in the induction of epigenetic changes in cancerous cells and the selection of less immunogenic clones as well as alterations in immune responses. Understanding the crosstalk between nascent transformed cells and cells of the immune system has led to the development of combinatorial immunotherapeutic strategies to combat cancer. The Handbook of Cancer and Immunology offers a comprehensive and up-to-date review of cancer immunology and immunotherapy, emphasizing key findings and clinically relevant data. This reference work is an essential resource for researchers, students, academics, and clinicians committed to advancing knowledge, diagnostics, and treatments in this vital field. 410 0$aHandbook of Cancer and Immunology,$x3091-3675 ;$v3 606 $aCancer 606 $aImmunology 606 $aImmunotherapy 606 $aTumors$xImmunological aspects 606 $aCancer$xTreatment 606 $aCancer Biology 606 $aImmunology 606 $aImmunotherapy 606 $aTumour Immunology 606 $aCancer Therapy 615 0$aCancer. 615 0$aImmunology. 615 0$aImmunotherapy. 615 0$aTumors$xImmunological aspects. 615 0$aCancer$xTreatment. 615 14$aCancer Biology. 615 24$aImmunology. 615 24$aImmunotherapy. 615 24$aTumour Immunology. 615 24$aCancer Therapy. 676 $a616.994071 700 $aRezaei$b Nima$0913363 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911031639303321 996 $aCancer and Surrounding Environment$94445282 997 $aUNINA