LEADER 03345nam 22006735 450 001 9911031631803321 005 20251008131402.0 010 $a3-032-00759-3 024 7 $a10.1007/978-3-032-00759-9 035 $a(CKB)41571836000041 035 $a(MiAaPQ)EBC32333419 035 $a(Au-PeEL)EBL32333419 035 $a(OCoLC)1545124657 035 $a(DE-He213)978-3-032-00759-9 035 $a(EXLCZ)9941571836000041 100 $a20251008d2025 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCancerous Cells $eImmunobiology of Tumors and Metastasis /$fedited by Nima Rezaei 205 $a1st ed. 2025. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2025. 215 $a1 online resource (1572 pages) 225 1 $aHandbook of Cancer and Immunology,$x3091-3675 ;$v2 311 08$a3-032-00758-5 327 $aIntroduction on Cancerous Cells and Metastasis -- Cancer Antigens Sources, Generation, and Presentation -- Cancer Stem Cells: Roles in Cancer Etiology -- Intercellular Communication in Cancer -- Intra-Tumor Cell Heterogeneity Different Immune Responses for Different Cells -- Crosstalk Between Cancer Associated Fibroblasts and Immune Cells -- Role of Extracellular Vesicles in Cancer Pathogenesis -- Apoptosis in Cancer -- Gut-Brain Axis.-Mucosal Exposome and Intestinal Carcinogenesis. 330 $aThe rapid flow of studies in the field of cancer and immunology during the last decades has increased our understanding of the interactions between the immune system and cancerous cells. In particular, it has been well-known that such interactions result in the induction of epigenetic changes in cancerous cells and the selection of less immunogenic clones as well as alterations in immune responses. Understanding the crosstalk between nascent transformed cells and cells of the immune system has led to the development of combinatorial immunotherapeutic strategies to combat cancer. The Handbook of Cancer and Immunology offers a comprehensive and up-to-date review of cancer immunology and immunotherapy, emphasizing key findings and clinically relevant data. This reference work is an essential resource for researchers, students, academics, and clinicians committed to advancing knowledge, diagnostics, and treatments in this vital field. 410 0$aHandbook of Cancer and Immunology,$x3091-3675 ;$v2 606 $aCancer 606 $aImmunology 606 $aImmunotherapy 606 $aTumors$xImmunological aspects 606 $aCancer$xTreatment 606 $aCancer Biology 606 $aImmunology 606 $aImmunotherapy 606 $aTumour Immunology 606 $aCancer Therapy 615 0$aCancer. 615 0$aImmunology. 615 0$aImmunotherapy. 615 0$aTumors$xImmunological aspects. 615 0$aCancer$xTreatment. 615 14$aCancer Biology. 615 24$aImmunology. 615 24$aImmunotherapy. 615 24$aTumour Immunology. 615 24$aCancer Therapy. 676 $a616.994079 700 $aRezaei$b Nima$0913363 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911031631803321 996 $aCancerous Cells$94444865 997 $aUNINA