LEADER 04956nam 22006375 450 001 9911031565903321 005 20251023173419.0 010 $a3-032-01585-5 024 7 $a10.1007/978-3-032-01585-3 035 $a(MiAaPQ)EBC32323710 035 $a(Au-PeEL)EBL32323710 035 $a(CKB)41528763300041 035 $a(OCoLC)1545644781 035 $a(DE-He213)978-3-032-01585-3 035 $a(EXLCZ)9941528763300041 100 $a20251001d2025 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBehavioral Neuroscience of Alcohol Addiction $eTranslational Studies and Human Phenotypes /$fedited by Wolfgang H. Sommer, Rainer Spanagel 205 $a1st ed. 2025. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2025. 215 $a1 online resource (473 pages) 225 1 $aCurrent Topics in Behavioral Neurosciences,$x1866-3389 ;$v72 311 08$a3-032-01584-7 327 $aPart 3 Experimental studies to human alcohol use and addiction -- Modelling Relapse Situations in the Human Laboratory -- Etiological Momentary Assessment of alcohol behaviour in humans -- The Dopamine System in Mediating Alcohol Effects in Humans -- Molecular imaging studies of alcohol use disorder -- The continuing challenges of studying parallel behaviors in humans and animal models -- MRI as an objective tool for animal human translation of alcohol effects -- Part 4 Treatment Approaches to AUD -- Approaches to AUD treatment based on Memory Retrieval and Counter Conditioning -- Approach bias retraining and other behavioral approaches in AUD -- New Approaches to Addiction Treatment based on Learning and Memory -- Brain stimulation to modulate alcohol behavior in animals and humans -- Role of the microbiome and the gut-brain axis in alcohol use disorder potential implication for treatment development. 330 $aBehavioral Neurobiology of Alcohol Addiction explores the forefront of addiction research, integrating fundamental neurobiological mechanisms with translational insights into human phenotypes. Alcohol addiction remains a major public health concern with extensive medical and societal implications. Understanding its intricate interplay between neurobiology, behavior, and treatment is essential for developing effective interventions. This edition is structured into two volumes: Basic Mechanisms and Animal Studies and Translational Studies and Human Phenotypes. The first volume examines addiction conceptualization, stress and reward systems, and chronic pain. It further explores the cellular, synaptic, and circuit-level consequences of alcohol, incorporating computational and neuroimaging approaches. It also addresses the replication crisis in preclinical research and proposes guidelines to mitigate its impact. The second volume shifts the focus to human studies, covering human laboratory approaches, ecological momentary assessment, molecular imaging, and the challenges of bridging preclinical and clinical research. The book also highlights emerging treatments, including psychological interventions, neuromodulation techniques, and the role of the gut-brain axis. Alcohol use fundamentally alters mood states via brain mechanisms?an insight widely acknowledged by experts and laypeople alike. However, debates surrounding the brain disease model of addiction have intensified in recent years. This collection of articles contributes to this ongoing discussion by reinforcing the importance of a neurobiological perspective in addiction science and demonstrating how advances in neuroscience translate into more effective therapeutic approaches. Written by leading experts in the field, both volumes provide a comprehensive yet accessible resource for addiction researchers, neuroscientists, clinicians, and students. The book aims to deepen the understanding of alcohol addiction and inspire new directions in research and treatment. 410 0$aCurrent Topics in Behavioral Neurosciences,$x1866-3389 ;$v72 606 $aPsychobiology 606 $aHuman behavior 606 $aNeuropharmacology 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aBehavioral Neuroscience 606 $aNeuropharmacology 606 $aTranslational Research 615 0$aPsychobiology. 615 0$aHuman behavior. 615 0$aNeuropharmacology. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 14$aBehavioral Neuroscience. 615 24$aNeuropharmacology. 615 24$aTranslational Research. 676 $a612.8 700 $aSommer$b Wolfgang H$01758878 701 $aSpanagel$b Rainer$01758879 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911031565903321 996 $aBehavioral Neuroscience of Alcohol Addiction$94443265 997 $aUNINA