LEADER 00936nam0-22003011i-450 001 990008114670403321 005 20240605151935.0 035 $aFED01000811467 035 $a(Aleph)000811467FED01 035 $a000811467 100 $a20050518d1958----km-y0itay50------ba 101 0 $afre 102 $aFR 105 $ay---n---001yy 200 1 $a<>travail des hommes libres dans l'antiquitè romaine$fJean Macqueron 205 $a2e ed. 210 $aAix$cCentre règional de documentation pèdagocique service des èditions$d1958 215 $a1 v.$d26 cm 676 $a340.5$v23$zita 700 1$aMacqueron,$bJean$0292367 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990008114670403321 952 $aFONDO PROFESSOR ANTONIO GUARINO IV H 84$bG/1963$fFGBC 952 $aXXI A 403$b55481$fFGBC 959 $aFGBC 996 $aTravail des hommes libres dans l'antiquitè romaine$9757623 997 $aUNINA LEADER 01493nam 22004093 450 001 9911028665103321 005 20250927060322.0 010 $a3-031-89669-6 035 $a(CKB)41002186600041 035 $a(MiAaPQ)EBC32317251 035 $a(Au-PeEL)EBL32317251 035 $a(EXLCZ)9941002186600041 100 $a20250927d2025 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGroup Sequential and Confirmatory Adaptive Designs in Clinical Trials 205 $a2nd ed. 210 1$aCham :$cSpringer,$d2025. 210 4$d©2025. 215 $a1 online resource (646 pages) 225 1 $aSpringer Series in Pharmaceutical Statistics Series 311 08$a3-031-89668-8 330 $aThis book provides an up-to-date review of the general principles and techniques of confirmatory adaptive designs, a generalization of group sequential designs.With these designs, interim analyses are performed in order to stop a trial prematurely under control of the Type I error rate. 410 0$aSpringer Series in Pharmaceutical Statistics Series 676 $a615.50724 700 $aWassmer$b Gernot$0755933 701 $aBrannath$b Werner$0755934 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911028665103321 996 $aGroup sequential and confirmatory adaptive designs in clinical trials$91523374 997 $aUNINA