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010   $a9786612455391
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100   $a19960912d1995      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 04$aThe molecular biology and pathology of elastic tissues /$f[editors Derek J. Chadwick and Jamie A. Goode]
210   $aChichester ;$aNew York $cJ. Wiley$d1995
215   $a1 online resource (373 p.)
225 1 $aCiba Foundation symposium ;$v192
300   $a"Symposium on the Molecular Biology and Pathology of Elastic Tissues, held at the Windsor Golf and Country Club, Nairobi, Kenya, 1-3 November 1994"--P. v.
300   $aEditors: Derek J. Chadwick and Jamie A. Goode.
311 08$a9780471957188 
311 08$a0471957186 
327   $aTHE MOLECULAR BIOLOGY AND PATHOLOGY OF ELASTIC TISSUES; Contents; Participants; Preface; Chairman's in trod uction; Molecular biophysics of elastin structure, function and pathology; UItrastructure of elastin; General discussion I; Structure of the elastin gene; Regulation of elastin synthesis in pathological states; Catalytic properties and structural components of lysyl oxidase; General discussion II; The structure and function of fibrillin; Elastin gene mutations in transgenic mice; Elastic fibre assembly: macromolecular interactions
327   $aThe 67 kDa spliced variant of b-galactosidase serves as a reusable protective chaperone for tropoelastinGeneral discussion Ill; Elastin in lung development and disease; Elastin and mechanoreceptor mechanisms with special reference to the mammalian carotid sinus; Skin elastic fibres: regulation of human elastin promoter activity in transgenic mice; Elastin in systemic and pulmonary hypertension; General discussion IV; Elastin in blood vessels; General discussion V; Elastase in the prevention of arterial ageing and the treatment of the rosclerosis
327   $aInteraction of tumour cells with elastin and the metastatic phenotypeA role for neutrophil elastase in solar elastosis; Closing reflections; Index of contributors; Subject Index
330   $aDrawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics include the structure, ultrastructure and function of elastin; elastin regulation; elastin's role in aging, lung development and disease and atherosclerosis; as well as related aspects of pharmacology and nutrition.
410  0$aCiba Foundation symposium ;$v192.
606   $aElastin$vCongresses
606   $aElastic tissue$xDiseases$xMolecular aspects$vCongresses
615  0$aElastin
615  0$aElastic tissue$xDiseases$xMolecular aspects
676   $a611/.0182
701   $aChadwick$b Derek$091632
701   $aGoode$b Jamie$0283336
712 02$aCiba Foundation.
712 12$aSymposium on the Molecular Biology and Pathology of Elastic Tissues$f(1994 :$eNairobi, Kenya)
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9911020245503321
996   $aThe molecular biology and pathology of elastic tissues$94422477
997   $aUNINA