LEADER 00729nam0-2200277---450- 001 990008499680403321 005 20070410110049.0 035 $a000849968 035 $aFED01000849968 035 $a(Aleph)000849968FED01 035 $a000849968 100 $a20070410d1981----km-y0itay50------ba 101 1 $aita$ceng 102 $aIT 105 $a--------001yy 200 1 $aTurbare l'universo$fFreeman Dyson 210 $aTorino$cBoringhieri$d1981 215 $a309 p.$d21 cm 700 1$aDyson,$bFreeman J.$f<1923- >$040445 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990008499680403321 952 $a10 A I 148$b122$fDINEL 959 $aDINEL 996 $aTurbare l'universo$9192647 997 $aUNINA LEADER 00881nam0 22003013i 450 001 996560470803316 005 20231120162244.0 010 $a978-88-229-0699-1 100 $a20211201d2021----||||0itac50 ba 101 $aita$ceng 102 $aIT 105 $ay 00 y 200 1 $a<> normativo, il giuridico e i compiti del diritto$fKarl N. Llewellyn$ga cura di Mariano Croce 210 1 $aMacerata$cQuodlibet$d2021 215 $a152 p.$d22 cm 225 2 $aIus$v6 410 0$aIus$v6 606 0 $aSociologia del diritto$2BNCF 676 $a340.115 700 1$aLLEWELLYN,$bKarl N.$0227440 702 1$aCROCE,$bMariano 801 0$aIT$bcba$gREICAT 912 $a996560470803316 951 $aXXII.1.E. 147$b95809 GIU$cXXII.1.E.$d557984 959 $aBK 969 $aGIU 996 $aNormativo, il giuridico e i compiti del diritto$93597020 997 $aUNISA LEADER 05137nam 22006614a 450 001 9911020167503321 005 20200520144314.0 010 $a9786610520411 010 $a9781280520419 010 $a1280520418 010 $a9783527605323 010 $a3527605320 010 $a9783527601530 010 $a3527601538 035 $a(CKB)1000000000019320 035 $a(EBL)482385 035 $a(OCoLC)68907055 035 $a(SSID)ssj0000119181 035 $a(PQKBManifestationID)11134330 035 $a(PQKBTitleCode)TC0000119181 035 $a(PQKBWorkID)10055958 035 $a(PQKB)10688941 035 $a(MiAaPQ)EBC482385 035 $a(Perlego)2754186 035 $a(EXLCZ)991000000000019320 100 $a20030814d2003 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCell membrane $ethe red blood cell as a model /$fYoshihito Yawata 210 $aWeinheim $cWiley-VCH$dc2003 215 $a1 online resource (457 p.) 300 $aDescription based upon print version of record. 311 08$a9783527304639 311 08$a3527304630 320 $aIncludes bibliographical references and index. 327 $aCell Membrane; Contents; Preface; Foreword; Acknowledgments; 1 Introduction: History of Red Cell Membrane Research; 1.1 Invention of Optical Microscopes and Their Application to Hematology; 1.2 Discovery of Hereditary Spherocytosis by Light Microscopy; 1.3 The Dawn of Red Cell Membrane Research; 1.4 Commencement of Membrane Protein Biochemistry: Introduction of Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis; 1.5 Elucidation of the Pathogenesis of Red Cell Membrane Disorders; 1.6 Genotypes of Red Cell Membrane Disorders 327 $a1.7 Reevaluation of Molecular Electron Microscopy for Phenotypes2 Composition of Normal Red Cell Membranes; 2.1 Introduction; 2.2 Membrane Lipids; 2.2.1 The Contents and Nature of Membrane Lipids; 2.2.2 Asymmetry of the Membrane Lipid Bilayer; 2.2.3 Membrane Fluidity; 2.2.4 Renewal of Membrane Lipids; 2.2.5 Interactions Between Membrane Lipids and Proteins; 2.2.6 Membrane Lipids as a Determinant of Red Cell Shape; 2.3 Membrane Proteins; 2.3.1 Separation and Identification of Membrane Proteins; 2.3.2 Membrane Proteins and Membrane Structure; 2.3.3 Membrane Proteins in the Red Cell Surface 327 $a2.3.4 Membrane Proteins and Membrane Functions2.3.4.1 Red Cell Morphology and Shape Change; 2.3.4.2 Red Cell Deformability; 2.3.4.3 Membrane Transport and Permeability; 3 Stereotactic Structure of Red Cell Membranes; 3.1 Historical Background to Membrane Models; 3.2 Ultrastructure of Red Cell Membranes; 3.2.1 Introduction; 3.2.2 Evaluation of the Cytoskeletal Network; 3.2.2.1 Electron Microscopy With the Negative Staining Method; 3.2.2.2 Electron Microscopy With the Quick-Freeze Deep-Etching (QFDE) Method; 3.2.2.3 Electron Microscopy With the Surface Replica (SR) Method 327 $a3.2.3 Integral Proteins Examined by Electron Microscopy With the Freeze Fracture Method3.2.4 Visualization of Glycophorins by Field Emission Scanning Electron Microscopy; 4 Skeletal Proteins; 4.1 ?- and ?-Spectrins; 4.1.1 Introduction; 4.1.2 Structure of Red Cell Spectrins; 4.1.3 Functions of Red Cell Spectrins; 4.1.4 Erythroid and Nonerythroid Spectrins; 4.2 Protein 4.1; 4.2.1 Structure of Protein 4.1; 4.2.2 Binding to Other Membrane Proteins; 4.2.3 Extensive Alternative Splicings; 4.2.4 Nonerythroid Protein 4.1 Isoforms; 4.3 Actin; 4.4 Other Minor Skeletal Proteins; 4.4.1 The p55 Protein 327 $a4.4.2 Adducin4.4.3 Dematin (Protein 4.9); 4.4.4 Tropomyosin; 4.4.5 Tropomodulin; 4.4.6 Other Membrane Proteins; 5 Integral Proteins; 5.1 Band 3; 5.1.1 Structure of Band 3; 5.1.2 Functions of Band 3; 5.1.2.1 Membrane Protein Binding by the Cytoplasmic Domain of Band 3; 5.1.2.2 Binding to Glycolytic Enzymes by the Cytoplasmic Domain of Band 3; 5.1.2.3 Binding to Hemoglobin by the Cytoplasmic Domain of Band 3; 5.1.2.4 Anion Exchange Channel by the Transmembrane Domain of Band 3; 5.1.2.5 Lateral and Rotational Mobility of Band 3; 5.1.2.6 Blood Type Antigens and Band 3 327 $a5.1.3 Band 3 in Nonerythyroid Cells 330 $aThis publication presents the structure and function of biological membranes to improve the understanding of cells in both normal and pathogenic states. Recently, vast amounts of new information have been accumulated, especially about pathological conditions, and there is now much evidence correlating genotypes and phenotypes in normal and disease states. This book surveys the most recent findings in research on the molecular biology, biochemistry, and genetics of the membranes of human red blood cells. 606 $aErythrocyte membranes 606 $aMembrane proteins 615 0$aErythrocyte membranes. 615 0$aMembrane proteins. 676 $a612.1/11 700 $aYawata$b Yoshihito$f1936-$01837912 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911020167503321 996 $aCell membrane$94416768 997 $aUNINA