LEADER 04306nam 2200721 a 450 001 9911019748103321 005 20200520144314.0 010 $a9786613679383 010 $a9781280768613 010 $a1280768614 010 $a9780470719053 010 $a0470719052 010 $a9780470716526 010 $a0470716525 035 $a(CKB)1000000000687592 035 $a(EBL)703751 035 $a(SSID)ssj0000715170 035 $a(PQKBManifestationID)11463731 035 $a(PQKBTitleCode)TC0000715170 035 $a(PQKBWorkID)10700059 035 $a(PQKB)10925434 035 $a(SSID)ssj0001034475 035 $a(PQKBManifestationID)11545098 035 $a(PQKBTitleCode)TC0001034475 035 $a(PQKBWorkID)11015808 035 $a(PQKB)21243831 035 $a(MiAaPQ)EBC703751 035 $a(OCoLC)264615365 035 $a(Perlego)2758620 035 $a(EXLCZ)991000000000687592 100 $a19851217d1957 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCiba Foundation Symposium on Drug Resistance in Micro-Organisms $emechanisms of development. /$feditors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor 210 $aBoston $cLittle, Brown$d[1957] 215 $a1 online resource (384 p.) 225 1 $aCiba Foundation symposium 300 $aDescription based upon print version of record. 311 08$a9780470722480 311 08$a0470722487 320 $aIncludes bibliographical references and indexes. 327 $aDRUG RESISTANCE IN MICRO-ORGANISMS; CONTENTS; Chairman's opening remarks; Aspects of the problem of drug resistance in bacteria; Discussion; Indirect selection and origin of resistance; Discussion; Genetic aspects of drug resistance; Discussion; Inheritance in single bacterial cells; Discussion; Penicillin-induced resistance to penicillin in cultures of Bacillus cereus; Discussion; Directed hereditary changes of fermentative properties of yeast by a specific substrate; Discussion; Multiple mechanisms of acquired drug resistance; Discussion 327 $aPhysiological (phenotypic) mechanisms responsible for drug resistanceDiscussion; Genetic and metabolic mechanisms underlying multiple levels of sulphonamide resistance in pneumococci; Discussion; The phenotypic expression of genes determining various types of drug resistance following their inheritance by sensitive bacteria; Discussion; Specific polyhydroxy compounds as cofactors of enzymic adaptation and its inheritance; Discussion; Development of resistance to streptomycin in Serratia marcescens; Discussion 327 $aDistribution of drug-resistant individuals in cultures of Mycobacterium tuberculosisDiscussion; Physiological adaptation of bacteria to antibiotics; Discussion; Drug resistance of staphylococci with special reference to penicillinase production; Discussion; On the identification of genetic and non-genetic variation in bacteria; Discussion; The reactions of the mutagenic alkylating agents with proteins and nucleic acids; Discussion; Genetics of two different mechanisms of resistance to colicins: resistance by loss of specific receptors and im- munity by transfer of colicinogenic factors 327 $aDiscussionGeneral Discussion; Chairman's closing remarks 330 8 $aThe Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. 410 0$aCiba Foundation symposium. 606 $aDrug resistance in microorganisms$vCongresses 615 0$aDrug resistance in microorganisms 676 $a615.1 701 $aWolstenholme$b G. E. W$g(Gordon Ethelbert Ward)$063039 701 $aO'Connor$b Cecilia M$g(Cecilia Mary),$f1927-$0207754 712 02$aCiba Foundation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911019748103321 996 $aCiba Foundation Symposium on Drug Resistance in Micro-Organisms$93004829 997 $aUNINA