LEADER 04673nam 2200697Ia 450 001 9911019728703321 005 20251116163410.0 010 $a9786612313172 010 $a9781282313170 010 $a1282313177 010 $a9780470029619 010 $a0470029617 010 $a9780470029602 010 $a0470029609 035 $a(CKB)1000000000811820 035 $a(EBL)470118 035 $a(SSID)ssj0000335220 035 $a(PQKBManifestationID)11256961 035 $a(PQKBTitleCode)TC0000335220 035 $a(PQKBWorkID)10272120 035 $a(PQKB)11296343 035 $a(MiAaPQ)EBC470118 035 $a(PPN)140090428 035 $a(OCoLC)476311750 035 $a(Perlego)2752953 035 $a(EXLCZ)991000000000811820 100 $a20090609d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBioinformatics for glycobiology and glycomics $ean introduction /$fedited by Claus-Wilhelm von der Lieth, Thomas Lutteke, and Martin Frank 210 $aChichester ;$aHoboken, NJ $cWiley-Blackwell$dc2009 215 $a1 online resource (505 p.) 300 $aDescription based upon print version of record. 311 08$a9780470016671 311 08$a0470016671 320 $aIncludes bibliographical references and index. 327 $aBioinformatics for Glycobiologyand Glycomics; Contents; List of Contributors; Preface; Section 1: Introduction; 1. Glycobiology, Glycomics and (Bio)Informatics; Section 2: Carbohydrate Structures; 2. Introduction to Carbohydrate Structure and Diversity; 3. Digital Representations of Oligo- and Polysaccharides; 4. Evolutionary Considerations in Studying the Sialome: Sialic; Section 3: Carbohydrate-active Enzymes and Glycosylation; 5. Carbohydrate-active Enzymes Database: Principles and Classification of Glycosyltransferases; 6. Other Databases Providing Glycoenzyme Data 327 $a7. Bioinformatics Analysis of Glycan Structures from a Genomic Perspective8. Glycosylation of Proteins; 9. Prediction of Glycosylation Sites in Proteins; Section 4: Experimental Methods - Bioinformatic Requirements; 10. Experimental Methods for the Analysis of Glycans and Their Bioinformatics Requirements; 11. Analysis of N- and O-Glycans of Glycoproteins by HPLC Technology; 12. Glycomic Mass Spectrometric Analysis and Data Interpretation Tools; 13. Software Tools for Semi-automatic Interpretation of Mass Spectra of Glycans 327 $a14. Informatics Concepts to Decode Structure-Function Relationships of Glycosaminoglycans15. NMR Databases and Tools for Automatic Interpretation of Spectra of Carbohydrates; 16. Automatic Spectrum Interpretation Based on Increment Rules: CASPER; 17. Interpretation of 13C NMR Spectra by Artificial Neural Network Techniques (NeuroCarb); Section 5: 3D Structures of Complex Carbohydrates; 18. Conformational Analysis of Carbohydrates - A Historical Overview; 19. Predicting Carbohydrate 3D Structures Using Theoretical Methods 327 $a20. Synergy of Computational and Experimental Methods in Carbohydrate 3D Structure Determination and ValidationSection 6: Protein-Carbohydrate Interaction; 21. Structural Features of Lectins and Their Binding Sites; 22. Statistical Analysis of Protein-Carbohydrate Complexes Contained in the PDB; Section 7: Appendices; Appendix 1: List of Available Websites; Appendix 2: Glossary; Index; Color Plates; Cover Page 330 $aThis book is the first to be dedicated to the bioinformatics of carbohydrates and glycoproteins. It provides an introduction to this emerging field of science both for the experimentalist working in glycobiology and glycomics, and also for the computer scientist looking for background information for the development of highly sophisticated algorithmic approaches. The book provides an overview of the state-of-the-art in the field, with reviews on databases, and the tools in use for analysis, interpretation, and prediction of the structures of complex carbohydrates, and demonstrates the value 606 $aGlycomics 606 $aGlycoconjugates$xResearch$xData processing 606 $aBioinformatics 615 0$aGlycomics. 615 0$aGlycoconjugates$xResearch$xData processing. 615 0$aBioinformatics. 676 $a572/.56 701 $aLieth$b Claus-Wilhelm von der$01838314 701 $aLu?tteke$b Thomas$01838315 701 $aFrank$b Martin$f1963-$01838316 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911019728703321 996 $aBioinformatics for glycobiology and glycomics$94417280 997 $aUNINA