LEADER 01099nam2-2200373---450 001 990000549930203316 005 20210324175749.0 010 $a88-339-5392-0 035 $a0054993 035 $aUSA010054993 035 $a(ALEPH)000054993USA01 100 $a20010706d1987----km y1itay5003----ba 101 0 $aita 102 $aIT 200 1 $a<<12.: >>Impresa$fFrancesco Silva$cMercato$fAntonio Sassu$cProduzione$fGianni Vaggi 210 $aTorino$cBoringhieri$d1987 215 $a262 p.$d23 cm 461 1$10010054980$12001$aDizionario di economia politica$v12 606 0 $aEconomia$xDizionari$2BNCF 676 $a330.0351 700 1$aSILVA,$bFrancesco$034957 701 1$aSASSU,$bAntonio$0483648 701 1$aVAGGI,$bGianni$0121812 702 1$aLUNGHINI,$bGiorgio 702 1$aD'ANTONIO,$bMariano 801 0$aIT$bsalbc$gISBD 912 $a990000549930203316 951 $a330.03 DIZ 1/12 (ISE II 182 12)$b3546 EC$cISE II$d00204802 951 $a300 330.03 LUN$b2128 DISES 959 $aBK 969 $aECO 969 $aDISES 996 $aImpresa$9885269 997 $aUNISA LEADER 02313nam 2200553 450 001 9910824364203321 005 20230803202037.0 010 $a90-485-2220-X 010 $a90-485-2219-6 035 $a(CKB)3710000000095944 035 $a(EBL)1773765 035 $a(SSID)ssj0001292345 035 $a(PQKBManifestationID)11742771 035 $a(PQKBTitleCode)TC0001292345 035 $a(PQKBWorkID)11283401 035 $a(PQKB)11201007 035 $a(MiAaPQ)EBC1773765 035 $a(Au-PeEL)EBL1773765 035 $a(CaPaEBR)ebr10852740 035 $a(OCoLC)923709418 035 $a(EXLCZ)993710000000095944 100 $a20140407h20142014 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe big reset $egold wars and the financial endgame /$fWillem Middelkoop 210 1$aAmsterdam, [Netherlands] :$cAmsterdam University Press,$d2014. 210 4$dİ2014 215 $a1 online resource (263 p.) 300 $aDescription based upon print version of record. 311 $a90-8964-599-3 320 $aIncludes bibliographical references. 327 $aThe history of money -- Central bankers : the alchemists of our time -- The history of the dollar -- A planet of debt -- The war on gold -- The big reset. 330 $aA system reset is imminent. Probably even before 2020, the world's financial system will need to find a different anchor. The dollar has been at the center of the monetary system since the Second World War, but decades of money printing have caused a gradual but relentless dollar devaluation. In a desperate attempt to maintain this dollar system, the United States has waged a secret war on gold since the 1960's. China and Russia have pierced through the American smokescreen around gold and the dollar and are no longer willing to continue lending to the United States. Both countries have been... 606 $aGold standard 606 $aCurrency convertibility 615 0$aGold standard. 615 0$aCurrency convertibility. 676 $a332.4222 700 $aMiddelkoop$b Willem$0608145 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910824364203321 996 $aThe big reset$94014281 997 $aUNINA LEADER 05541nam 2200733Ia 450 001 9911019575803321 005 20200520144314.0 010 $a9786612302442 010 $a9781282302440 010 $a1282302442 010 $a9783527611942 010 $a3527611940 010 $a9783527608706 010 $a3527608702 035 $a(CKB)1000000000687512 035 $a(EBL)481286 035 $a(OCoLC)468787369 035 $a(SSID)ssj0000343201 035 $a(PQKBManifestationID)11255581 035 $a(PQKBTitleCode)TC0000343201 035 $a(PQKBWorkID)10289226 035 $a(PQKB)10946255 035 $a(MiAaPQ)EBC481286 035 $a(Perlego)2775983 035 $a(EXLCZ)991000000000687512 100 $a20050629d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aStandards of mouse model phenotyping /$fedited by Martin Hrabede Angelis, Pierre Chambon, and Steve Brown 210 $aWeinheim $cWiley-VCH$dc2006 215 $a1 online resource (359 p.) 300 $aDescription based upon print version of record. 311 08$a9783527310319 311 08$a3527310312 320 $aIncludes bibliographical references and index. 327 $aStandards of Mouse Model Phenotyping; Foreword; Table of Contents; Preface; 1 Characterizing Hearing in Mice; 1.1 Introduction; 1.2 Behavioral Tests of Hearing; 1.3 Physiological Tests of Hearing; 1.4 Anatomy of the Ear; 1.5 Conclusions; Acknowledgements; 2 Molecular Phenotyping: Gene Expression Profiling; 2.1 Why this Screen? Medical and Biological Relevance; 2.2 Examples: Diseases of Mouse and Man; 2.3 Diagnostic Methods: History and State of the Art; 2.4 Technical Requirements for Screening Protocols (Short): First and Second Line Approaches; 2.5 Logistics (Whom, When, How Many, Why) 327 $a2.5.1 Choice of Platform2.5.2 Biological Samples; 2.6 Trouble Shooting; 2.6.1 Preparation of Hybridization Target; 2.6.2 Critical Issues of Chip Hybridization; 2.6.3 Image Processing and Array Design; 2.7 Short-term Outlook; 3 Screening for Bone and Cartilage Phenotypes in Mice; 3.1 Introduction; 3.1.1 The Skeleton; 3.1.2 Skeletal Development in the Embryo; 3.1.3 Growth and Maintenance of Bone and Cartilage; 3.1.4 Diseases Involving Cartilage and Bone; 3.1.5 The Mouse as a Model for Skeletal Diseases; 3.2 Screening Protocols; 3.2.1 Morphological Analysis; 3.2.1.1 Protocol 327 $a3.2.2 X-Ray Analysis3.2.2.1 General; 3.2.2.2 Imaging; 3.2.2.3 X-Ray Analysis; 3.2.2.4 Protocol; 3.2.3 DXA-Analysis; 3.2.3.1 General; 3.2.3.2 Advantages; 3.2.3.3 Disadvantages; 3.2.3.4 Small Animal Applications; 3.2.3.5 Precision and Accuracy; 3.2.3.6 Considerations; 3.2.3.7 Protocol; 3.2.4 Biochemical Bone Markers; 3.2.4.1 Clinical Utility of Biochemical Markers of Bone Turnover in Small Animals; 3.2.4.2 Mouse Markers of Bone Turnover/Metabolism and Hormonal Regulation; 3.2.4.3 Variability/Sensitivity/Sample Choice; 3.2.4.4 Which Markers Should be Used During the Screen? 327 $a3.2.5 Advanced Small Animal Imaging Techniques3.2.5.1 pQCT; 3.2.5.2 ?CT; 3.2.5.3 ?MRI; 3.2.5.4 Whole-mount Skeletal Preparations; 3.2.5.5 Histomorphometry; 3.2.5.6 Miscellaneous; 3.2.5.7 Order of the Tests; 3.3 Conclusion; List of Abbreviations; Appendix; ?CT Volumetric Data Processing; MRI Principles; 4 Clinical Chemical Screen; 4.1 Introduction; 4.1.1 Relevance of the Screen; 4.1.2 Biology and Medical Application; 4.1.2.1 Biology of Clinical Chemical Parameters; 4.1.2.2 Medical Application; 4.2 Diseases in Mouse and Humans; 4.2.1 Diagnostic Impact of Clinical Chemistry 327 $a4.2.2 Clinical Chemistry in Selected Disorders4.2.2.1 Hypercholesterolemia; 4.2.2.2 Albuminuria; 4.2.2.3 Acute Myeloid Leukemia (AML); 4.3 Clinical Chemistry as Diagnostic Tool; 4.3.1 History; 4.3.2 State of the Art; 4.4 Technical Requirements and Screening Protocols; 4.4.1 Technical Requirements; 4.4.1.1 Blood Collection; 4.4.1.2 Sample Preparation; 4.4.1.3 Sample Analysis; 4.4.2 Screening Protocols; 4.4.2.1 Primary Screen; 4.4.2.2 Secondary Screen; 4.4.2.3 Tertiary Screen; 4.5 Logistics of the Screen; 4.5.1 General Considerations; 4.5.2 Lessons from ENU Mutants; 4.6 Trouble Shooting 327 $a4.6.1 Factors Interfering In Vivo 330 $aThis is the first book in the field of mouse genetics to provide comprehensive and standardized methods for the characterization of laboratory mice. The editor is Director of the German Mouse Clinic and member of the Project Committee of the German National Genome Research Network and provides here a brief introduction to the mouse as a model for diseases and functional analysis of genes and proteins. Throughout, he focuses on the characterization of mouse models using the latest phenotyping methods, with the different areas presented in a clearly structured and easily accessible manner. 606 $aMice as laboratory animals 606 $aMice$xGenetics 606 $aTransgenic mice 606 $aPhenotype 615 0$aMice as laboratory animals. 615 0$aMice$xGenetics. 615 0$aTransgenic mice. 615 0$aPhenotype. 676 $a599.353135 701 $aHrabe de Angelis$b Martin$01840589 701 $aChambon$b Pierre$01840590 701 $aBrown$b Stephen D. 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