LEADER 01825nam 2200505I 450 001 9910703588303321 005 20150304140229.0 035 $a(CKB)5470000002431814 035 $a(OCoLC)904343315 035 $a(EXLCZ)995470000002431814 100 $a20150304j201408 ua 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMulti-mission system analysis for planetary entry (M-SAPE) version 1 /$fJamshid Samareh [and thirteen others] 210 1$aHampton, Virginia :$cNational Aeronautics and Space Administration, Langley Research Center,$dAugust 2014. 215 $a1 online resource (x, 124 pages) $ccolor illustrations 225 1 $aNASA/TM ;$v2014-218507 300 $aTitle from title screen (viewed March 4, 2015). 300 $a"August 2014." 320 $aIncludes bibliographical references (pages 74-75). 517 $aMulti-mission system analysis for planetary entry 606 $aSample return missions$2nasat 606 $aAtmospheric entry$2nasat 606 $aAerodynamic stability$2nasat 606 $aSystems analysis$2nasat 606 $aSystems integration$2nasat 606 $aFlight mechanics$2nasat 615 7$aSample return missions. 615 7$aAtmospheric entry. 615 7$aAerodynamic stability. 615 7$aSystems analysis. 615 7$aSystems integration. 615 7$aFlight mechanics. 700 $aSamareh$b Jamshid$01393023 712 02$aLangley Research Center, 712 02$aUnited States.$bNational Aeronautics and Space Administration, 801 0$bGPO 801 1$bGPO 906 $aBOOK 912 $a9910703588303321 996 $aMulti-mission system analysis for planetary entry (M-SAPE) version 1$93448614 997 $aUNINA LEADER 04067nam 2200733Ia 450 001 9911019558403321 005 20200520144314.0 010 $a9786612123870 010 $a9781282123878 010 $a1282123874 010 $a9780470985571 010 $a0470985577 010 $a9780470985564 010 $a0470985569 035 $a(CKB)1000000000377303 035 $a(EBL)470483 035 $a(SSID)ssj0000360016 035 $a(PQKBManifestationID)11244187 035 $a(PQKBTitleCode)TC0000360016 035 $a(PQKBWorkID)10317795 035 $a(PQKB)10624946 035 $a(MiAaPQ)EBC470483 035 $a(OCoLC)184983387 035 $a(Perlego)2768065 035 $a(EXLCZ)991000000000377303 100 $a20070626d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aFatty acids and lipotoxicity in obesity and diabetes /$feditors: Gregory Bock and Jamie Goode 210 $aLondon $cJohn Wiley$d2007 215 $a1 online resource (223 p.) 225 1 $aNovartis Foundation symposium ;$v286 300 $aDescription based upon print version of record. 311 08$a9780470057643 311 08$a0470057645 320 $aIncludes bibliographical references and index. 327 $aFATTY ACIDS AND LIPOTOXICITY IN OBESITY AND DIABETES; Contents; Chair's introduction; Transcriptional control of energy homeostasis through the PGC1 coactivators; DISCUSSION; Human obesity and insulin resistance: lessons from experiments of nature; DISCUSSION; Lipid-induced metabolic dysfunction in skeletal muscle; DISCUSSION; Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes; DISCUSSION; The role of lipin 1 in adipogenesis and lipid metabolism; DISCUSSION; The role of the AMP-activated protein kinase in the regulation of energy homeostasis; DISCUSSION 327 $aEndoplasmic reticulum stress and inflammation in obesity and type 2 diabetesDISCUSSION; The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis; DISCUSSION; Fatty acid transport in adipocytes and the development of insulin resistance; DISCUSSION; Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking; DISCUSSION; Lipid storage and mobilization pathways in yeast; DISCUSSION; Cide proteins and the development of obesity; DISCUSSION; General discussion I; Visualizing brown adipose tissue with FDG-PET 327 $aAdiponectin and adiponectin receptors in obesity-linked insulin resistanceDISCUSSION; Anti-inflammatory and antidiabetic roles of PPARy; DISCUSSION; Final Discussion; Nutrition, ageing and lipotoxicity; Contributor Index; Subject Index 330 $aThe potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic ß cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics in 410 0$aNovartis Foundation symposium ;$v286. 606 $aLipids$xMetabolism$vCongresses 606 $aFatty acids$vCongresses 606 $aAdipose tissues$vCongresses 606 $aObesity$vCongresses 606 $aDiabetes$vCongresses 615 0$aLipids$xMetabolism 615 0$aFatty acids 615 0$aAdipose tissues 615 0$aObesity 615 0$aDiabetes 676 $a612.397 701 $aBock$b Gregory$0322650 701 $aGoode$b Jamie$0283336 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911019558403321 996 $aFatty acids and lipotoxicity in obesity and diabetes$94420406 997 $aUNINA