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101 0 $aeng
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181   $ctxt
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183   $acr
200 00$aIntracellular pathogens II $eRickettsiales /$fedited by Guy H. Palmer, Abdu F. Azad ; lead editor, Ming Tan
210   $aWashington, D.C. $cASM Press$dc2012
215   $a1 online resource (0 p.)
300   $aDescription based upon print version of record.
311 08$a1-55581-677-0 
320   $aIncludes bibliographical references and index.
327   $aClinical disease : current treatment and new challenges / J. Stephen Dumler -- Public health : Rickettsial infections and epidemiology / Jennifer H. McQuiston and Christopher D. Paddock -- Phylogeny and comparative genomics : the shifting landscape in the genomics era / Joseph J. Gillespie ... [et al.] -- Invasion of the mammalian host : early events at the cellular and molecular levels / Juan J. Martinez -- Establishing intracellular infection : escape from the phagosome and intracellular colonization (Rickettsiaceae) / Matthew D. Welch, Shawna C. O. Reed, and Cat M. Haglund -- Establishing intracellular infection : modulation of host cell functions (Anaplasmataceae) / Jason A. Carlyon -- Rickettsial physiology and metabolism in the face of reductive evolution / Jonathon P. Audia -- Innate immune response and inflammation : roles in pathogenesis and protection (Rickettsiaceae) / Sanjeev K. Sahni, Elena Rydkina, and Patricia J. Simpson-Haidaris -- Innate immune response and inflammation : roles in pathogenesis and protection (Anaplasmataceae) / Nahed Ismail and Heather L. Stevenson -- Adaptive immune responses to infection and opportunities for vaccine development (Rickettsiaceae) / Gustavo Valbuena -- Adaptive immune responses to infection and opportunities for vaccine development (Anaplasmataceae) / Susan M. Noh and Wendy C. Brown -- Persistence and antigenic variation / Kelly A. Brayton -- Transmission and the determinants of transmission efficiency / Shane M. Ceraul -- The way forward : improving genetic systems / Ulrike G. Munderloh ... [et al.].
330   $a"A current review of basic research on Rickettsiales biology and pathogenesis in one comprehensive volume.  Details the scientific knowledge about how these obligate intracellular bacteria invade, survive and replicate inside eukaryotic cells. Describes the spectrum of disease caused by an infection and the role of vectors in transmission. Discusses protective and pathologic immune responses and establishment of persistent infection. Describes the latest developments including genomics and progress in vaccine development. Serves as a significant research book for scientists, physicians, medical students, public health professionals, epidemiologists, biocomputational scientists and government policy makers. " 
606   $aRickettsial diseases
606   $aRickettsiaceae
615  0$aRickettsial diseases.
615  0$aRickettsiaceae.
676   $a616.9/22
701   $aPalmer$b Guy$g(Guy Hughes),$f1955-$01841092
701   $aAzad$b Abdu F$01841093
701   $aTan$b Ming$01838091
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9911019404103321
996   $aIntracellular pathogens II$94420713
997   $aUNINA