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010   $a9786610408818
010   $a9781280408816
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100   $a20060912d2006      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aGene-environment interactions $efundamentals of ecogenetics /$fedited by Lucio G. Costa, David L. Eaton
210   $aHoboken, N.J. $cWiley-Liss$dc2006
215   $a1 online resource (577 p.)
300   $aDescription based upon print version of record.
311 08$a9780471467816 
311 08$a0471467812 
320   $aIncludes bibliographical references (p. 451-529) and index.
327   $aGene-Environment Interactions; Contents; Foreword; Acknowledgments; Contributors; PART I; Chapter 1. Introduction; Chapter 2. Ecogenetics: Historical Perspectives; Chapter 3. Tools of Ecogenetics; Chapter 4. Epidemiologic Approaches; Chapter 5. Statistical Issues in Ecogenetic Studies; PART II; Chapter 6. Overview of Section II; Chapter 7. Polymorphisms in Cytochrome P450 and Flavin-Containing Monooxygenase Genes; Chapter 8. Polymorphisms in Xenobiotic Conjugation; Chapter 9. Paraoxonase, Butyrylcholinesterase, and Epoxide Hydrolase; Chapter 10. DNA Repair Enzymes
327   $aChapter 11. Receptors and Ion ChannelsPART III; Chapter 12. Overview of Section III; Chapter 13. Lung Cancer; Chapter 14. Gastrointestinal Cancers; Chapter 15. Neurodegenerative Diseases; Chapter 16. Cardiovascular Disease; Chapter 17. Type 2 Diabetes; Chapter 18. Infectious Disease Ecogenetics; Chapter 19. Genetic Variation, Diet, and Disease Susceptibility; Chapter 20. Genetic Determinants of Addiction to Alcohol, Tobacco, and Drugs of Abuse; PART IV; Chapter 21. Overview of Section IV; Chapter 22. Ethical Issues in Ecogenetics; Chapter 23. Social and Psychological Aspects of Ecogenetics
327   $aChapter 24. Legal IssuesChapter 25. Risk Assessment and the Impact of Ecogenetics; Bibliography; Index
330   $aUnderstanding the play between heredity and environment, and relating it to disease causation, is the task of ecogenetics. Gene-Environment Interactions: Fundamentals of Ecogenetics presents the first comprehensive survey of this discipline, reflecting its relationship with toxicology, epidemiology, pharmacology, public health, and other medical and biological fields.Divided into four sections, the text elucidates key basic and advanced topics:* Section 1 covers fundamentals, including the history of the discipline, a discussion of the molecular laboratory tools currently available
606   $aGenetic toxicology
606   $aEcological genetics
606   $aEnvironmentally induced diseases$xGenetic aspects
606   $aDisease susceptibility$xGenetic aspects
606   $aHuman genetics$xVariation
615  0$aGenetic toxicology.
615  0$aEcological genetics.
615  0$aEnvironmentally induced diseases$xGenetic aspects.
615  0$aDisease susceptibility$xGenetic aspects.
615  0$aHuman genetics$xVariation.
676   $a616.042
701   $aCosta$b Lucio G.$f1954-$0747662
701   $aEaton$b David L$066581
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9911019383503321
996   $aGene-environment interactions$94422618
997   $aUNINA