LEADER 04298nam 2200685 a 450 001 9911019220303321 005 20200520144314.0 010 $a9780470715413 010 $a0470715413 010 $a9780470715109 010 $a0470715103 035 $a(CKB)1000000000688116 035 $a(EBL)739074 035 $a(OCoLC)775868806 035 $a(SSID)ssj0000668033 035 $a(PQKBManifestationID)11470644 035 $a(PQKBTitleCode)TC0000668033 035 $a(PQKBWorkID)10698417 035 $a(PQKB)10552887 035 $a(MiAaPQ)EBC739074 035 $a(Perlego)2765226 035 $a(EXLCZ)991000000000688116 100 $a20790320d1979 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aOxygen free radicals and tissue damage 210 $aAmsterdam ;$aNew York $cExcerpta Medica$d1979 215 $a1 online resource (392 p.) 225 1 $aCiba Foundation symposium ;$v65 (new ser.) 300 $aDescription based upon print version of record. 311 08$a9780444900630 311 08$a0444900632 320 $aIncludes bibliographical references and indexes. 327 $aOxygen Free Radicals and Tissue Damage; Contents; Chairman's introduction; The chemistry of dioxygen and its reduction products; Discussion; Hydroxyl radicals and biological damage in uitro: what relevance in uivo?; Discussion; Reaction rates of superoxide radicals with the essential amino acids; Discussion; Formation of copper-superoxide complexes; Interactions between iron metabolism and oxygen activation; Discussion; Superoxide dismutases: defence against endogenous superoxide radical; Discussion; Glutathione peroxidase: fact and fiction; Discussion; Biosynthesis of prostaglandins 327 $aDiscussionMechanisms of protection against the damage produced in biological systems by oxygen-derived radicals; Discussion; Zinc and NADPH-oxidation-dependent lipid peroxidation; Caeruloplasmin and serum antioxidant activity; Inflammatory cells and zinc; Lipid peroxidation: detection in viuo and in vitro through the formation of saturated hydrocarbon gases; Discussion; Dioxygen and the vitamin K-dependent synthesis of prothrombin; Discussion; Specific induction of pulmonary indoleamine 2,3-dioxygenase by bacterial lipopolysaccharide; Discussion 327 $aOxygen consumption by stimulated human neutrophilsDiscussion; Defects in the oxidative killing of microorganisms by phagocytic leukocytes; Discussion; The role of myeloperoxidase in the microbicidal activity of polymorphonuclear leukocytes; Discussion; Fertilization of sea urchin eggs; The lactoperoxidase-thiocyanate-hydrogen peroxide antibacterium system; The pulmonary and extrapulmonary effects of ozone; Discussion; The pathology and biochemistry of paraquat; Discussion; Phagocyte-produced free radicals: roles in cyto- toxicity and inflammation; Discussion; GENERAL DISCUSSION 327 $aCarbonyl groups and carcinogenesisThe identity of the superoxide radical anion species; Closing remarks; Index of contributors; Subject index 330 8 $aThe Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. 410 0$aCiba Foundation symposium ;$vnew ser. 65. 606 $aActive oxygen in the body$vCongresses 606 $aActive oxygen$xToxicology$vCongresses 606 $aPathology, Cellular$vCongresses 606 $aRadicals (Chemistry)$xPhysiological effect$vCongresses 615 0$aActive oxygen in the body 615 0$aActive oxygen$xToxicology 615 0$aPathology, Cellular 615 0$aRadicals (Chemistry)$xPhysiological effect 676 $a574.1/921 712 02$aCiba Foundation. 712 12$aSymposium on Oxygen Free Radicals and Tissue Damage 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911019220303321 996 $aOxygen free radicals and tissue damage$91954841 997 $aUNINA