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100   $a19901029d1991      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aClinical applications of TGF-[beta]
210   $aChichester ;$aNew York $cWiley$d1991
215   $a1 online resource (266 p.)
225 1 $aCiba Foundation symposium ;$v157
300   $aBased on the Symposium on Clinical Applications of TGF-[beta], held at the Ciba Foundation, London, June 12-14, 1990.
300   $aEditors: Gregory R. Bock and Joan Marsh.
300   $a"A Wiley-Interscience publication."
311 08$a9780471928119 
311 08$a0471928119 
320   $aIncludes bibliographical references and indexes.
327   $aCLINICAL APPLICATIONS OF TGF-B; Contents; Introduction; Multiple forms of TGF-B: distinct promoters and differential expression; TGF-B receptors; Mechanisms in TGF-B action; Regulation of epithelial proliferation by TGF-B; Latent forms of TGF-B: molecular structure and mechanisms of action; General discussion I : The role of TGF-B in the nervous system; TGF-B: a possible autocrine immune regulator; TGF-B and wound healing; General discussion II : A stimulatory effect of transforming growth factors on skin tumour devdopmcnt in vivo; The effects of TGF-B on bone
327   $aTGF-B1 and fibroblast growth factors selectively up-regulate tissue-specific fetal genes in cardiac muscle cellsEffects of TGF-Bs in the liver : cell proliferation and fibrogenesis; Role of TGF-B1 in experimental glomerulonephritis; The role of TGF-B in pulmonary fibrosis; In vivo and in vitro effects of TGF-B1 on normal and neoplastic haemopoiesis; Expression of TGF-B2 in human glioblastoma : a role in resistance to immune rejection?; Index of contributors; Subject index
330   $aTGF-beta, originally identified as a transforming growth factor with similar properties, is now known to exist as a family of factors with similar properties. These factors promote cell proliferation in some tissue types or conditions and induce cell differentiation in others. Features the latest information on the TGF-beta family and its receptors. Describes correlations between TGF-beta and certain cancers, including glioblastomas. Also contains reports of preliminary investigations of clinical applications for TGF-beta in many diseases, including leukemia and its use to accelerate wound hea
410  0$aCiba Foundation symposium ;$v157.
606   $aTransforming growth factors-beta$xTherapeutic use$vCongresses
615  0$aTransforming growth factors-beta$xTherapeutic use
676   $a615/.7
701   $aBock$b Gregory$0322650
701   $aMarsh$b Joan$091633
712 12$aSymposium on Clinical Applications of TGF-[beta]$f(1990 :$eCiba Foundation)
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9911019210403321
996   $aClinical applications of TGF-$94417849
997   $aUNINA