LEADER 00873nam0-2200301---450- 001 990009968370403321 005 20150525145430.0 010 $a9780691136745 035 $a000996837 035 $aFED01000996837 035 $a(Aleph)000996837FED01 035 $a000996837 100 $a20150525d2012----km-y0itay50------ba 101 0 $aeng 102 $aUS 105 $a--------001yy 200 1 $aAgent-based and individual-based modeling$ea practical introduction$fSteven F. Railsback and Volker Grimm 210 $aPrinceton ; Oxford : ,$cPrinceton University Press$d2012 215 $aXVIII, 329 p.$d26 cm 676 $a006.3$v22$zita 700 1$aRailsback,$bSteven F. 701 1$aGrimm,$bVolker 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990009968370403321 952 $a60 006.3 B 1$b14463$fFAGBC 959 $aFAGBC 997 $aUNINA LEADER 05231nam 2200733 a 450 001 9910956306903321 005 20200520144314.0 010 $a9786611742843 010 $a9781281742841 010 $a1281742848 010 $a9781847422774 010 $a1847422772 035 $a(CKB)1000000000411567 035 $a(EBL)419297 035 $a(OCoLC)232609472 035 $a(SSID)ssj0000210488 035 $a(PQKBManifestationID)11184924 035 $a(PQKBTitleCode)TC0000210488 035 $a(PQKBWorkID)10290153 035 $a(PQKB)11378485 035 $a(OCoLC)1250435135 035 $a(MdBmJHUP)musev2_80270 035 $a(DE-B1597)646786 035 $a(DE-B1597)9781847422774 035 $a(MiAaPQ)EBC419297 035 $a(Perlego)3564989 035 $a(EXLCZ)991000000000411567 100 $a20080326d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aNew Labour/hard labour? $erestructuring and resistance inside the welfare industry /$fedited by Gerry Mooney and Alex Law 205 $a1st ed. 210 $aBristol, U.K. $cPolicy Press$d2007 215 $a1 online resource (313 p.) 300 $aDescription based upon print version of record. 311 08$a9781861348340 311 08$a1861348347 320 $aIncludes bibliographical references and index. 327 $aLiverpool social workers on strikeConclusions: resources of hope for a re-engaged social work; 10. Working 'for' welfare in the grip of the 'iron' Chancellor: modernisation and resistance in the Department for Work and Pensions; Introduction; 'Modernisation' and 'reform': the vision of a 'true opportunity society'; 'Prudence for a purpose': review, rationalisation, reform; Transforming welfare: transforming welfare work; Resistance and struggle: striking 'for' welfare?; Conclusions; 11. Working in the non-profit welfare sector: contract culture, partnership, Compacts and the 'shadow state' 327 $aManagerialism in higher educationRestructuring the academic labour process; Market competition for academic labour power; Academic trade unionism and resistance; Conclusions; 8. The paradox of 'professionalisation' and 'degradation' in welfare work: the case of nursery nurses; Introduction; Labouring for the 'social investment state'; Uncovering the nursery nursing labour process; Resisting New Labour: the 2004 Scottish nursery nurses strike; Legacies of the strike; Conclusions; 9. Social work today: a profession worth fighting for?; Introduction; Deskilling of social work 327 $aIntroductionThe NHS and the nursing labour process in context; Direct and indirect forms of control over the nursing labour process; The labour process, moral management and professional self-regulation; Limits of control; Conclusions; 6. 'I didn't come into teaching for this!': the impact of the market on teacher professionalism; Introduction; 'Market, Market, Market'; Academy and trust schools; Reducing inequality: size matters; Conclusions; 7. Ambiguities and resistance:academic labour and the commodification of higher education; Higher education under New Labour 327 $aThe 'Third Way' and the employment relationship'Modernising government': work intensification the New Labour way; Delivering public services: 'best value' in police call handling; Conclusions; 4. Acts of distrust? Suppor tworkers' experiences in PFI hospital schemes; Introduction; Contracting out and PFI under New Labour; Changes to pay and conditions; Alienation, belonging and the quality of services; Class consciousness and individual forms of resistance; Collective forms of resistance; Conclusions; 5. Control and resistance at the ward-face: contesting the nursing labour process 327 $aCover; New Labour/Hard Labour?; Contents; Acknowledgements; List of abbreviations; List of contributors; 1. New Labour, 'modernisation' and welfare worker resistance; Introduction; New Labour and public sector 'modernisation'; Welfare workers: resisting New Labour; The organisation of the book; 2. Strenuous welfarism:restructuring the welfare labour process; Introduction; Models of X-inefficiency; A neo-Taylorist welfare labour process?; Neoliberalism and strenuous welfarism; Conclusions; 3. A 'Third Way'? Industrial relations under New Labour; Introduction 330 $aThis book provides the first critically informed discussion of work and workers in the UK welfare sector under New Labour. It examines the changing nature of work and explores the context of industrial relations across the welfare industry. 606 $aHuman services personnel$zGreat Britain 606 $aIndustrial relations$zGreat Britain 606 $aPublic welfare$zGreat Britain 607 $aGreat Britain$xPolitics and government$y1997-2007 615 0$aHuman services personnel 615 0$aIndustrial relations 615 0$aPublic welfare 676 $a361.60941 701 $aMooney$b Gerry$f1960-$0147461 701 $aLaw$b Alex$01803120 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910956306903321 996 $aNew Labour$94349724 997 $aUNINA LEADER 05427nam 2200697Ia 450 001 9911019144803321 005 20200520144314.0 010 $a9781118514672 010 $a111851467X 010 $a9781283644419 010 $a128364441X 010 $a9781118514696 010 $a1118514696 010 $a9781118514641 010 $a1118514645 035 $a(CKB)2670000000242721 035 $a(EBL)1023289 035 $a(OCoLC)815389182 035 $a(SSID)ssj0000718997 035 $a(PQKBManifestationID)11411431 035 $a(PQKBTitleCode)TC0000718997 035 $a(PQKBWorkID)10745898 035 $a(PQKB)10343672 035 $a(OCoLC)813987805 035 $a(MiAaPQ)EBC1023289 035 $a(Perlego)1012612 035 $a(EXLCZ)992670000000242721 100 $a20120430h20122013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aLysosomal storage disorders $ea practical guide /$fedited by Atul Mehta, Bryan Winchester 210 $aChichester, West Sussex $cWiley-Blackwell$d2012, c2013 215 $a1 online resource (209 p.) 300 $aDescription based upon print version of record. 311 08$a9780470670873 311 08$a0470670878 320 $aIncludes bibliographical references and index. 327 $aLysosomal Storage Disorders: A Practical Guide; Copyright; Contents; List of Contributors; Preface; Foreword; Part 1 General Aspects of Lysosomal Storage Diseases; 1 The Lysosomal System: Physiology and Pathology; Introduction; The greater lysosomal system; Lysosomal diseases; References; 2 Clinical Aspects and Clinical Diagnosis; Introduction; Clinical presentation; References; 3 Laboratory Diagnosis of Lysosomal Storage Diseases; Referral to specialist laboratory; Preliminary screening tests on urine or blood; Diagnosis of lysosomal enzyme defects 327 $aLSDs due to defects in non-enzymatic proteinsNeuronal ceroid lipofuscinoses (NCLs); Molecular genetic testing; Prenatal diagnosis; Prospects; Acknowledgements; References; 4 Genetics of Lysosomal Storage Disorders and Counselling; Introduction; Genes, proteins, stored substrates, clinical phenotypes and diagnosis; Incidence and prevalence; Populations at a high-risk; Burden of illness; Population screening and diagnostic methods; Counselling issues; References; 5 Classification of Lysosomal Storage Diseases; Basis of classification of lysosomal storage diseases; Acknowledgements 327 $aPart 2 The Individual Diseases6 Gaucher Disease; A representative case history; Gaucher disease; Epidemiology; Etiology and pathogenesis:genetic basis; Clinical forms; Diagnosis; Biomarkers; Routine follow-up of patients; Enzyme replacement therapy (ERT) for Gaucher disease: alglucerase and imiglucerase; Dosing regimens; Malignancies; Global shortage of imiglucerase (June 2009); Other treatment options: substrater eduction therapy (SRT); Summary; References; 7 Fabry Disease; Epidemiology; Genetic basis; Pathophysiology; Clinical presentation; Natural history; Laboratory diagnosis; Treatment 327 $aTreatment guidelinesFurther reading; 8 The Gangliosidoses; References; 9 Metachromatic Leukodystrophy and Globoid Cell Leukodystrophy; MLD and GLD; Case studies; Epidemiology; Genetics; Pathophysiology; Clinical presentation; Diagnosis by MRI; Laboratory diagnosis; Treatment; Natural history studies; References; 10 Types A and B Niemann-Pick Disease; Representative case histories; Epidemiology; Genetics; Pathophysiology; Clinical presentation; Natural history; Laboratory diagnosis; Treatment; Acknowledgements and conflicts of interest; References; 11 Niemann-Pick Disease Type C 327 $aCase historiesEpidemiology; Genetic basis; Pathophysiology; Clinical presentation; Natural history; Laboratory diagnosis; Treatment; References; 12 The Mucopolysaccharidoses; Epidemiology; Genetic basis; Pathophysiology; Clinical presentation; Natural history; Laboratory diagnosis; Treatment; Acknowledgements; References; 13 Pompe Disease; Case histories; Confusing nomenclature; Epidemiology; Genetic basis; Pathophysiology; Clinical presentation; Natural history; Enzymatic and molecular diagnosis; Treatment; Acknowledgment; Selected literature; 14 Glycoproteinoses; Epidemiology 327 $aPathophysiology 330 $a Awareness of lysomal storage disorders needs to be raised and there is very substantial pharmaceutical interest to do so. The disorders are often viewed as obscurities but in fact they are treatable. Enzyme replacement therapy is available for four of the disorders and will be available for a further three disorders in the course of the next year. Substrate reduction therapy is licensed for one of them but in the course of the next 12 months it will be licensed for two others and a new form of substrate reduction therapy is being introduced. These diseases present to a very wide range 606 $aLysosomal storage diseases 606 $aMetabolism$xDisorders 615 0$aLysosomal storage diseases. 615 0$aMetabolism$xDisorders. 676 $a571.6/55 701 $aMehta$b Atul B$01672754 701 $aWinchester$b Bryan$01840917 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911019144803321 996 $aLysosomal storage disorders$94420488 997 $aUNINA